{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:49:00Z","timestamp":1761864540634,"version":"3.41.2"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:00:00Z","timestamp":1687305600000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,6,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A brown recluse spider (BRS) bite is challenging to confirm, but can be clinically diagnosed by considering the location, the season of the year and the clinical manifestations. We described a 26-year-old male who presented after a BRS bite with a skin lesion, bruising, severe swelling and diffuse blisters on the right lower extremity after 3\u00a0days. This case should be considered in the differential diagnosis of necrotizing fasciitis. Although spider bite poisoning is rare, proper diagnosis and management are important because, in some cases, it can have devastating outcomes.<\/jats:p>","DOI":"10.1093\/jscr\/rjad357","type":"journal-article","created":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T20:49:04Z","timestamp":1687466944000},"source":"Crossref","is-referenced-by-count":2,"title":["Massive dermal ulcerative lesions because of brown recluse spider bite: a rare case report and review of literature"],"prefix":"10.1093","volume":"2023","author":[{"given":"Mahdi","family":"Fakhar","sequence":"first","affiliation":[{"name":"Iranian National Registry Center for Lophomoniasis and Toxoplasmosis, Mazandaran University of Medical Sciences , Sari , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahriar","family":"Alian","sequence":"additional","affiliation":[{"name":"Antimicrobial Resistance Research Center , Department of Infectious Diseases, , Sari , Iran"},{"name":"Mazandaran University of Medical Sciences , Department of Infectious Diseases, , Sari , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ashkan","family":"Zakariaei","sequence":"additional","affiliation":[{"name":"Student Research Committee , Babol Branch, , Babol , Iran"},{"name":"Islamic Azad University , Babol Branch, , Babol , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatemeh","family":"Nourzad","sequence":"additional","affiliation":[{"name":"Toxicology Ward , Qaemshahr Razi Hospital, , Sari , Iran"},{"name":"Mazandaran University of Medical Sciences , Qaemshahr Razi Hospital, , Sari , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zakaria","family":"Zakariaei","sequence":"additional","affiliation":[{"name":"Toxicology and Forensic Medicine Division , Mazandaran Registry Center for Opioids Poisoning, Antimicrobial Resistance Research Center, Imam Khomeini Hospital, , Sari , Iran"},{"name":"Mazandaran University of Medical Sciences , Mazandaran Registry Center for Opioids Poisoning, Antimicrobial Resistance Research Center, Imam Khomeini Hospital, , Sari , Iran"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,6,21]]},"reference":[{"key":"2023062211021913100_ref1","doi-asserted-by":"crossref","first-page":"355","DOI":"10.3390\/toxins11060355","article-title":"Brown spider (Loxosceles) venom toxins as potential biotools for the development of novel therapeutics","volume":"11","author":"Chaves-Moreira","year":"2019","journal-title":"Toxins"},{"key":"2023062211021913100_ref2","doi-asserted-by":"crossref","first-page":"164","DOI":"10.3390\/toxins12030164","article-title":"Forty years of the description of brown spider venom phospholipases-D","volume":"12","author":"Gremski","year":"2020","journal-title":"Toxins"},{"volume-title":"Brown Recluse Spider Toxicity","year":"2021","author":"Anoka","key":"2023062211021913100_ref3"},{"key":"2023062211021913100_ref4","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/s40409-017-0097-8","article-title":"Highlights in the knowledge of brown spider toxins","volume":"23","author":"Chaves-Moreira","year":"2017","journal-title":"J Venom Anim Toxins Incl Trop Dis"},{"key":"2023062211021913100_ref5","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1177\/1203475417708164","article-title":"Acute cutaneous necrosis: a guide to early diagnosis and treatment","volume":"21","author":"Karimi","year":"2017","journal-title":"J Cutan Med Surg"},{"key":"2023062211021913100_ref6","doi-asserted-by":"crossref","first-page":"e31","DOI":"10.1016\/j.jemermed.2009.08.055","article-title":"Suspected brown recluse envenomation: a case report and review of different treatment modalities","volume":"41","author":"Andersen","year":"2011","journal-title":"J Emerg"},{"key":"2023062211021913100_ref7","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1016\/j.jpeds.2009.07.021","article-title":"Brown recluse spider (Loxosceles reclusa) envenomation leading to acute hemolytic anemia in six adolescents","volume":"156","author":"McDade","year":"2010","journal-title":"J Pediatr"},{"key":"2023062211021913100_ref8","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1080\/15563650.2020.1739701","article-title":"Cutaneous-hemolytic loxoscelism following brown recluse spider envenomation: new understandings","volume":"58","author":"Loden","year":"2020","journal-title":"Clin Toxicol"},{"key":"2023062211021913100_ref9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.injury.2005.07.009","article-title":"Brown recluse spider bite to the leg","volume":"37","author":"Bhatti","year":"2006","journal-title":"Injury Extra"},{"key":"2023062211021913100_ref10","doi-asserted-by":"crossref","first-page":"623","DOI":"10.1016\/j.toxicon.2011.09.009","article-title":"Seasonality of brown recluse spiders, Loxosceles reclusa, submitted by the general public: implications for physicians regarding loxoscelism diagnoses","volume":"58","author":"Vetter","year":"2011","journal-title":"Toxicon"},{"key":"2023062211021913100_ref11","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1097\/01.ASW.0000504578.06579.20","article-title":"Nonhealing wounds caused by brown spider bites: application of hyperbaric oxygen therapy","volume":"29","author":"Hadanny","year":"2016","journal-title":"Adv Skin Wound Care"},{"key":"2023062211021913100_ref12","doi-asserted-by":"crossref","first-page":"e932378","DOI":"10.12659\/AJCR.932378","article-title":"Viscerocutaneous loxoscelism manifesting with myocarditis: a case report","volume":"22","author":"Langner","year":"2021","journal-title":"Am J Case Rep"},{"key":"2023062211021913100_ref13","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.toxicon.2022.03.015","article-title":"Brown spider (Loxosceles sp.) bite and COVID-19: a case report","volume":"212","author":"Ferreira","year":"2022","journal-title":"Toxicon"},{"key":"2023062211021913100_ref14","first-page":"bcr2016215832","article-title":"Rare case of dermonecrosis caused by a recluse spider bite in Europe","volume":"2016","author":"Cachia","year":"2016","journal-title":"Case Rep"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/6\/rjad357\/50666764\/rjad357.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/6\/rjad357\/50666764\/rjad357.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,22]],"date-time":"2023-06-22T20:49:12Z","timestamp":1687466952000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad357\/7204594"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,6,1]]},"references-count":14,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,6,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad357","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2023,6]]},"published":{"date-parts":[[2023,6,1]]},"article-number":"rjad357"}}