{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T07:01:24Z","timestamp":1782543684767,"version":"3.54.5"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T00:00:00Z","timestamp":1691107200000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Few reports have described a submucosal tumor (SMT)-like colon tumor together with appendiceal cancer. Moreover, some appendiceal tumors may exhibit a cecal protuberance. Here, we report an uncommon case of appendiceal cancer with an SMT-like tumor, which was a protuberant lesion in the ascending colon. To our knowledge, this is the first report in Japan. Our case was a 50-year-old man with an ascending colon tumor presented at our hospital for further evaluation of this lesion. This was discovered as a cystic lesion near the ascending colon on colonoscopy. Our initial diagnosis was an ascending colon SMT-like tumor, and our treatment strategy was laparoscopic resection. The differential diagnosis was appendiceal cancer or mucocele. Postoperative pathological findings led to a diagnosis of adenocarcinoma of the appendix. The postoperative course was uneventful, and the patient was followed up with computed tomography and blood sampling on an outpatient basis.<\/jats:p>","DOI":"10.1093\/jscr\/rjad390","type":"journal-article","created":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T08:43:32Z","timestamp":1691138612000},"source":"Crossref","is-referenced-by-count":1,"title":["Appendiceal cancer showing a submucosal tumor-like morphology in the ascending colon on colonoscopy: a case report"],"prefix":"10.1093","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9027-730X","authenticated-orcid":false,"given":"Kurodo","family":"Koshino","sequence":"first","affiliation":[{"name":"Department of Surgery, Institute of Gastroenterology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryosuke","family":"Nakagawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Gastroenterology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kimitaka","family":"Tani","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Gastroenterology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shimpei","family":"Ogawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Gastroenterology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomoko","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Department of Surgical Pathology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuji","family":"Inoue","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Gastroenterology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shigeki","family":"Yamaguchi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Institute of Gastroenterology, Tokyo Women\u2019s Medical University , 162-86668-1, Kawada-cho, Shinjuku-ku, Tokyo , Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2023,8,4]]},"reference":[{"key":"2023080408432595900_ref1","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1097\/00000658-199401000-00009","article-title":"The natural history of surgically treated primary adenocarcinoma of the appendix","volume":"219","author":"Nitecki","year":"1994","journal-title":"Ann Surg"},{"key":"2023080408432595900_ref2","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1007\/s00464-003-9255-x","article-title":"Appendix tumors in the era of laparoscopic appendectomy","volume":"18","author":"Bucher","year":"2004","journal-title":"Surg Endosc"},{"key":"2023080408432595900_ref3","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1007\/BF02236899","article-title":"Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies","volume":"41","author":"Connor","year":"1998","journal-title":"Dis Colon Rectum"},{"key":"2023080408432595900_ref4","first-page":"244","article-title":"Primary appendiceal malignancies: rare but important","volume":"111","author":"Rutledge","year":"1992","journal-title":"Surgery"},{"key":"2023080408432595900_ref5","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1443-1661.2009.00905.x","article-title":"Endoscopic submucosal dissection for gastric submucosal tumor, endoscopic sub-tumoral dissection","volume":"21","author":"Hoteya","year":"2009","journal-title":"Dig Endosc"},{"key":"2023080408432595900_ref6","doi-asserted-by":"crossref","first-page":"e7","DOI":"10.1053\/j.gastro.2010.11.044","article-title":"Submucosal tumor of cecum?","volume":"141","author":"Liang","year":"2011","journal-title":"Gastroenterology"},{"key":"2023080408432595900_ref7","doi-asserted-by":"crossref","first-page":"e12","DOI":"10.1053\/j.gastro.2011.11.042","article-title":"A submucosal tumor in the cecum. Appendiceal mucocele mimicking a submucosal tumor","volume":"142","author":"Cheng","year":"2012","journal-title":"Gastroenterology"},{"key":"2023080408432595900_ref8","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1007\/BF02562650","article-title":"A 25-year review of adenocarcinoma of the appendix. A frequently perforating carcinoma","volume":"31","author":"Cerame","year":"1988","journal-title":"Dis Colon Rectum"},{"key":"2023080408432595900_ref9","doi-asserted-by":"crossref","first-page":"39027","DOI":"10.1038\/srep39027","article-title":"The management and prognostic prediction of adenocarcinoma of appendix","volume":"6","author":"Xie","year":"2016","journal-title":"Sci Rep"},{"key":"2023080408432595900_ref10","doi-asserted-by":"crossref","first-page":"W590","DOI":"10.2214\/AJR.12.9260","article-title":"Appendiceal mucocele: a diagnostic dilemma in differentiating malignant from benign lesions with CT","volume":"201","author":"Wang","year":"2013","journal-title":"AJR Am J Roentgenol"},{"key":"2023080408432595900_ref11","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1016\/S0016-5107(89)72860-1","article-title":"The volcano sign of appendiceal mucocele","volume":"35","author":"Hamilton","year":"1989","journal-title":"Gastrointest Endosc"},{"key":"2023080408432595900_ref12","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1385\/IJGC:36:3:177","article-title":"Primary minute invasive de novo colonic adenocarcinoma appearing as submucosal tumor","volume":"36","author":"Zenda","year":"2005","journal-title":"Int J Gastrointest Cancer"},{"key":"2023080408432595900_ref13","doi-asserted-by":"crossref","first-page":"A30","DOI":"10.1016\/j.cgh.2012.11.009","article-title":"Dome-type carcinoma of the colon masquerading a submucosal tumor","volume":"11","author":"Yamada","year":"2013","journal-title":"Clin Gastroenterol Hepatol"},{"key":"2023080408432595900_ref14","first-page":"104","article-title":"Adenocarcinoma of appendix mimicking acute appendicitis: a case report and literature review","volume":"5","author":"Al-Zawi","year":"2018","journal-title":"EJPMR"},{"key":"2023080408432595900_ref15","doi-asserted-by":"crossref","first-page":"1507","DOI":"10.1111\/j.1463-1318.2012.03052.x","article-title":"Surgical management of primary appendiceal malignancy","volume":"14","author":"Whitfield","year":"2012","journal-title":"Colorectal Dis"},{"key":"2023080408432595900_ref16","first-page":"381","article-title":"Mucinous appendiceal tumors: clinical review","volume":"82","author":"Stephenson","year":"1985","journal-title":"J Med Soc N J"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/8\/rjad390\/51036403\/rjad390.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/8\/rjad390\/51036403\/rjad390.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,4]],"date-time":"2023-08-04T08:43:49Z","timestamp":1691138629000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad390\/7236915"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":16,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad390","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,8]]},"published":{"date-parts":[[2023,8]]},"article-number":"rjad390"}}