{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:19Z","timestamp":1753877239493,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,8,4]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Benign Prostatic Hypertrophy (BPH) affects at least one-third of men over 60\u00a0years. A giant prostatic hyperplasia (GPH) is a prostate enlargement that exceeds 500 g. We present a case of a 72-year-old man with a GPH volume of 1280\u00a0ml, referred to our hospital for a worsening of the lower urinary tract symptoms (LUTS), bilateral loin pain and kidney failure. Although the patient had a negligible post-void residual urine, he had bilateral hydronephrosis. The patient was managed conservatory because of a high anesthesiologic risk but a bilateral percutaneous nephrostomy was placed soon due to kidney function worsening. The presence of serious comorbidities and the resolution of the loin pain and the renal failure, achieved first with the nephrostomy and then with periodic replacement of ureteral stents, along with an improvement of the LUTS obtained with medical therapy, have oriented us towards a conservative management of the patient.<\/jats:p>","DOI":"10.1093\/jscr\/rjad422","type":"journal-article","created":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T15:20:10Z","timestamp":1692717610000},"source":"Crossref","is-referenced-by-count":0,"title":["Conservative approach for a giant prostatic hyperplasia of 1280\u00a0ml: a case report and literature review"],"prefix":"10.1093","volume":"2023","author":[{"given":"Luigi","family":"Quaresima","sequence":"first","affiliation":[{"name":"Division of Urology , Civitanova Marche Hospital , Civitanova Marche , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pietro","family":"Tramanzoli","sequence":"additional","affiliation":[{"name":"Department of Clinical and Specialist Sciences , Division of Urology, , Ancona , Italy"},{"name":"Polytechnic University of the Marche Region Medical School , Division of Urology, , Ancona , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Fasanella","sequence":"additional","affiliation":[{"name":"Department of Life , Health and Environmental Sciences, , L'Aquila , Italy"},{"name":"University of L'Aquila , Health and Environmental Sciences, , L'Aquila , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Benedetto","family":"Galosi","sequence":"additional","affiliation":[{"name":"Department of Clinical and Specialist Sciences , Division of Urology, , Ancona , Italy"},{"name":"Polytechnic University of the Marche Region Medical School , Division of Urology, , Ancona , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Willy","family":"Giannubilo","sequence":"additional","affiliation":[{"name":"Division of Urology , Civitanova Marche Hospital , Civitanova Marche , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,8,23]]},"reference":[{"key":"2023082323512104900_ref1","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1186\/1471-2490-13-18","article-title":"Successful minimaly-invasive management of a case of giant prostatic hypertrophy associated with recurrent nephrogenic adenoma of the prostate","volume":"13","author":"Learney","year":"2013","journal-title":"BMC Urol"},{"key":"2023082323512104900_ref2","doi-asserted-by":"crossref","first-page":"242","DOI":"10.4103\/npmj.npmj_69_20","article-title":"Management of a giant prostatic enlargement: case report and review of the literature","volume":"27","author":"Ojewola","year":"2020","journal-title":"Niger Postgrad Med J"},{"key":"2023082323512104900_ref3","first-page":"237","article-title":"Giant prostatic hyperplasia and its causes","volume":"26","author":"Anglickis","year":"2020","journal-title":"Acta Med Litu"},{"key":"2023082323512104900_ref4","first-page":"3","article-title":"Giant prostatic hyperplasia: case presentation of the second largest prostate adenoma","volume":"27","author":"Dincer","year":"2021","journal-title":"African J Urol"},{"key":"2023082323512104900_ref5","first-page":"183","article-title":"Giant prostatic hyperplasia. A case report and literature review","volume":"70","author":"De Silva-Guti\u00e9rrez","year":"2010","journal-title":"Rev Mex Urol"},{"key":"2023082323512104900_ref6","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.ajur.2015.10.004","article-title":"A case of giant prostatic hyperplasia","volume":"3","author":"Wang","year":"2016","journal-title":"Asian J Urol"},{"key":"2023082323512104900_ref7","doi-asserted-by":"crossref","first-page":"336","DOI":"10.1016\/0090-4295(93)90628-N","article-title":"A case of giant prostatic hyperplasia","volume":"42","author":"Fishman","year":"1993","journal-title":"Urology"},{"key":"2023082323512104900_ref8","first-page":"795","article-title":"Hipertrofia Gigante de pr\u00f3stata: 2.410 gramos de peso y 24 cm de di\u00e1metro [Giant hypertrophy of the prostate: 2,410 grams of weight and 24 cm in diameter]","volume":"50","author":"Medina P\u00e9rez","year":"1997","journal-title":"Arch Esp Urol"},{"key":"2023082323512104900_ref9","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1097\/JCMA.0000000000000088","article-title":"Is intravesical prostatic protrusion a risk factor for hydronephrosis and renal insufficiency in benign prostate hyperplasia patients?","volume":"82","author":"Lu","year":"2019","journal-title":"J Chin Med Assoc"},{"key":"2023082323512104900_ref10","doi-asserted-by":"crossref","first-page":"e3","DOI":"10.1016\/j.urology.2015.11.016","article-title":"Giant prostatic hyperplasia: case report of 3987 mL","volume":"88","author":"Dom\u00ednguez","year":"2016","journal-title":"Urology"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/8\/rjad422\/51234559\/rjad422.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/8\/rjad422\/51234559\/rjad422.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T23:51:38Z","timestamp":1692834698000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad422\/7248987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2023,8,4]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad422","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2023,8]]},"published":{"date-parts":[[2023,8]]},"article-number":"rjad422"}}