{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T22:43:30Z","timestamp":1774478610457,"version":"3.50.1"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2023,7,30]],"date-time":"2023-07-30T00:00:00Z","timestamp":1690675200000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,7,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Only a few instances of giant gastrointestinal stromal tumors and even fewer cases of such tumors with intra-tumoral bleeding have ever been reported. This report represents a case with both giant size and intra-tumoral spontaneous hemorrhage. Here a 42-year-old male patient presented with abdominal pain and abdominal distention of 5-month duration. The distention had fast growth over 1\u00a0month before the hospital presentation. Physical examination showed a conjunctival pallor and an ill-defined abdominal mass. A contrast-enhanced computed tomography (CT) scan showed a huge intra-abdominal mass with variable enhancements. Surgical exploration was done and a huge mass measuring 10.5\u00a0kg with dimensions of 32\u2009\u00d7\u200930\u2009\u00d7\u200915\u00a0cm was excised en-bloc with distal gastrectomy.<\/jats:p>","DOI":"10.1093\/jscr\/rjad427","type":"journal-article","created":{"date-parts":[[2023,7,30]],"date-time":"2023-07-30T22:25:56Z","timestamp":1690755956000},"source":"Crossref","is-referenced-by-count":4,"title":["Giant gastric GIST with fast-growing mass after intra-tumoral bleeding"],"prefix":"10.1093","volume":"2023","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9913-6770","authenticated-orcid":false,"given":"Yeabsera M","family":"Duguma","sequence":"first","affiliation":[{"name":"Addis Ababa University College of Health Sciences, Department of Surgery, , Addis Ababa , Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tesfahun A","family":"Seid","sequence":"additional","affiliation":[{"name":"All Africa Leprosy Rehabilitation and Training Center Department of Surgery, , Addis Ababa , Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonas G","family":"Shumiye","sequence":"additional","affiliation":[{"name":"Addis Ababa University College of Health Sciences, Department of Pathology, , Addis Ababa , Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tesfaye A","family":"Dinagde","sequence":"additional","affiliation":[{"name":"Addis Ababa University College of Health Sciences, Department of Surgery, , Addis Ababa , Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Segni","family":"Kejela","sequence":"additional","affiliation":[{"name":"Addis Ababa University College of Health Sciences, Department of Surgery, , Addis Ababa , Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,7,29]]},"reference":[{"key":"2023073022254731100_ref1","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1053\/j.semdp.2006.09.001","article-title":"Gastrointestinal stromal tumors: pathology and prognosis at different sites","volume":"23","author":"Miettinen","year":"2006","journal-title":"Semin Diagn Pathol"},{"key":"2023073022254731100_ref2","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1159\/000494303","article-title":"Clinical presentation of gastrointestinal stromal tumors","volume":"34","author":"Menge","year":"2018","journal-title":"Visc Med"},{"key":"2023073022254731100_ref3","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1016\/j.ijsu.2014.02.004","article-title":"Gastrointestinal stromal tumors (GIST) related emergencies","volume":"12","author":"Sorour","year":"2014","journal-title":"Int J 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aggressive behavior: KIT mutation analysis and clinical correlates of 120 gastrointestinal stromal tumors","volume":"9","author":"Antonescu","year":"2003","journal-title":"Clin Cancer Res"},{"key":"2023073022254731100_ref8","first-page":"6170861","article-title":"Gigantic GIST: a case of the largest gastrointestinal stromal tumor found to date","volume":"2018","author":"Mohamed","year":"2018","journal-title":"Case Rep Surg"},{"key":"2023073022254731100_ref9","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1272\/jnms.JNMS.2022_89-108","article-title":"Successful transcatheter arterial embolization to control intratumoral hemorrhage in clear-cell sarcoma of the kidney","volume":"89","author":"Uchimura","year":"2022","journal-title":"J Nippon Med Sch"},{"key":"2023073022254731100_ref10","doi-asserted-by":"crossref","first-page":"1094","DOI":"10.1016\/j.jvir.2021.04.007","article-title":"Life-threatening intratumoral hemorrhage in an infant with hepatoblastoma successfully treated with hepatic arterial embolization","volume":"32","author":"Ronsley","year":"2021","journal-title":"J Vasc Interv Radiol"},{"key":"2023073022254731100_ref11","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1148\/radiology.135.2.7367626","article-title":"Computed tomography of acute intratumoral hemorrhage","volume":"135","author":"Zimmerman","year":"1980","journal-title":"Radiology"},{"key":"2023073022254731100_ref12","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1007\/s11605-008-0501-3","article-title":"How do I do it: surgical management of gastrointestinal stromal tumors","volume":"12","author":"Raut","year":"2008","journal-title":"J Gastrointest Surg"},{"key":"2023073022254731100_ref13","doi-asserted-by":"crossref","first-page":"830","DOI":"10.5124\/jkma.2007.50.9.830","article-title":"Clinical practice guideline for adequate diagnosis and effective treatment of gastrointestinal stromal tumor in Korea","volume":"50","author":"Kang","year":"2007","journal-title":"J Korean Med Assoc"},{"key":"2023073022254731100_ref14","doi-asserted-by":"crossref","first-page":"1411","DOI":"10.1016\/j.humpath.2008.06.025","article-title":"Risk stratification of patients diagnosed with a gastrointestinal stromal tumor","volume":"39","author":"Joensuu","year":"2008","journal-title":"Hum Pathol"},{"key":"2023073022254731100_ref15","doi-asserted-by":"crossref","first-page":"100812","DOI":"10.1016\/j.tranon.2020.100812","article-title":"Prognostic indicators for gastrointestinal stromal tumors: a review","volume":"13","author":"Zhang","year":"2020","journal-title":"Transl Oncol"},{"key":"2023073022254731100_ref16","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.annonc.2021.09.005","article-title":"ESMO guidelines committee, EURACAN, and GENTURIS. Electronic address: clinicalguidelines@esmo.org. Gastrointestinal stromal tumors: ESMO-EURACAN-GENTURIS clinical practice guidelines for diagnosis, treatment, and follow-up","volume":"33","author":"Casali","year":"2022","journal-title":"Ann Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/7\/rjad427\/51005409\/rjad427.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/7\/rjad427\/51005409\/rjad427.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,30]],"date-time":"2023-07-30T22:26:04Z","timestamp":1690755964000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad427\/7233654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":16,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2023,7,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad427","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,7]]},"published":{"date-parts":[[2023,7]]},"article-number":"rjad427"}}