{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,14]],"date-time":"2025-12-14T16:14:37Z","timestamp":1765728877324,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2023,9,20]],"date-time":"2023-09-20T00:00:00Z","timestamp":1695168000000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,9,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Symptomatic giant ganglioneuromas with mediastinal compression are rare, complicating its management with significant morbidity and mortality risks. A meticulous multidisciplinary preoperative planning is pivotal in ensuring success. We describe a case of a 30-year-old man with a giant posterior mediastinal mass with compression and displacement of the mediastinal structures. Biopsy confirmed a ganglioneuroma and patient underwent excision. Surgery was challenging in view of the size and adherence to the local structures. Haemodynamic instabilities were encountered necessitating a pre-emptive femoral-femoral cannulation for CPB. A piece-meal debulking of the tumour was performed, complicated with massive haemorrhage requiring autologous blood transfusion using an intraoperative blood salvage device. The patient recovered and was discharged home well at Day 8. A thorough pre-operative planning involving a multidisciplinary approach, an understanding of the surgical anatomy as well as anticipating impending complications is of paramount importance\u00a0 in the management of this particular case.<\/jats:p>","DOI":"10.1093\/jscr\/rjad524","type":"journal-article","created":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T18:52:01Z","timestamp":1695408721000},"source":"Crossref","is-referenced-by-count":1,"title":["Operative challenges in a gigantic ganglioneuroma of the posterior mediastinum with mediastinal compression"],"prefix":"10.1093","volume":"2023","author":[{"given":"Muhammad Abid","family":"Amir","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine, Universiti Teknologi MARA Sungai Buloh Campus , 47000 Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4524-8013","authenticated-orcid":false,"given":"Mohamed Izzad","family":"Isahak","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine, Universiti Teknologi MARA Sungai Buloh Campus , 47000 Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isqandar","family":"Adnan","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Faculty of Medicine, Universiti Teknologi MARA Sungai Buloh Campus , 47000 Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohd Zamrin","family":"Dimon","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery, Faculty of Medicine, Universiti Teknologi MARA Sungai Buloh Campus , 47000 Selangor, Malaysia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,9,20]]},"reference":[{"key":"2023092218514624300_ref1","doi-asserted-by":"crossref","first-page":"126","DOI":"10.5152\/balkanmedj.2012.099","article-title":"A case of posterior mediastinal ganglioneuroma: the importance of preoperative multiplanar radiological imaging","volume":"30","author":"K\u0131z\u0131lda\u011f","year":"2013","journal-title":"Balkan Med J"},{"key":"2023092218514624300_ref2","first-page":"1773","volume-title":"Clinical Oncology","author":"Aisner","year":"2004","edition":"3rd"},{"key":"2023092218514624300_ref3","first-page":"672","volume-title":"Greenfield\u2019s Neuropathology","author":"Lantos","edition":"7th"},{"key":"2023092218514624300_ref4","first-page":"620","volume-title":"Surgical Pathology of the Nervous System and Its Coverings","author":"Burger","year":"2002","edition":"4th"},{"key":"2023092218514624300_ref5","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1148\/rg.242035077","article-title":"Posterior mediastinal ganglioneuroma","volume":"24","author":"Forsythe","year":"2004","journal-title":"Radiographics"},{"key":"2023092218514624300_ref6","doi-asserted-by":"crossref","first-page":"1905","DOI":"10.1002\/1097-0142(20010515)91:10<1905::AID-CNCR1213>3.0.CO;2-4","article-title":"Metabolic activity and clinical features of primary ganglioneuromas","volume":"91","author":"Geoerger","year":"2001","journal-title":"Cancer"},{"key":"2023092218514624300_ref7","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/j.athoracsur.2010.04.086","article-title":"Surgical treatment for pediatric mediastinal neurogenic tumors","volume":"90","author":"Fraga","year":"2010","journal-title":"Ann Thorac Surg"},{"key":"2023092218514624300_ref8","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1053\/stcs.2000.16738","article-title":"Neurogenic tumors of the mediastinum","volume":"12","author":"Reeder","year":"2000","journal-title":"Semin Thorac Cardiovasc Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/9\/rjad524\/51714662\/rjad524.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/9\/rjad524\/51714662\/rjad524.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,22]],"date-time":"2023-09-22T18:52:06Z","timestamp":1695408726000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad524\/7279093"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2023,9,5]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad524","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2023,9]]},"published":{"date-parts":[[2023,9]]},"article-number":"rjad524"}}