{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:07Z","timestamp":1753877227905,"version":"3.41.2"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T00:00:00Z","timestamp":1697328000000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["# 5T32CA126607"],"award-info":[{"award-number":["# 5T32CA126607"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,10,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Multicystic peritoneal mesothelioma (BMPM) is a rare, usually benign tumor that arises from peritoneal mesothelial cells that most commonly occurs in women of reproductive age. Pathogenesis of these tumors is thought to come from chronic inflammation from prior surgery, endometriosis, trauma, or recurrent peritonitis. Here we report a case of primary splenic BMPM in a 20-year-old male with no past medical or surgical history and without any typical risk factors for this condition. He underwent an open splenectomy without complication. Pathology revealed an 18 \u00d7 4 \u00d7 11\u00a0cm3 spleen with a cyst occupying 75% of the splenic surface. Sections revealed a multilocular cyst with trabeculated walls and immunohistochemical staining positive for cytokeratin (AE1\/AE3) consistent with BMPM. One year post operatively he remains asymptomatic; however, his interval computed tomography (CT) scan revealed several sub centimeter nodules that either represents small splenules or neoplastic implants. These will be followed with close interval imaging.<\/jats:p>","DOI":"10.1093\/jscr\/rjad551","type":"journal-article","created":{"date-parts":[[2023,10,15]],"date-time":"2023-10-15T17:47:26Z","timestamp":1697392046000},"source":"Crossref","is-referenced-by-count":0,"title":["Primary splenic multicystic peritoneal mesothelioma in a young healthy male"],"prefix":"10.1093","volume":"2023","author":[{"given":"Matthew D","family":"Price","sequence":"first","affiliation":[{"name":"Department of Surgery, Johns Hopkins School of Medicine , 1800 Orleans Street, Baltimore, MD 21287 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuait","family":"Nair","sequence":"additional","affiliation":[{"name":"The Johns Hopkins University School of Medicine , Baltimore, MD 21287 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"James","family":"Harris","sequence":"additional","affiliation":[{"name":"Department of Surgery, Johns Hopkins School of Medicine , 1800 Orleans Street, Baltimore, MD 21287 , United States"},{"name":"Department of Surgery, The Johns Hopkins Howard County General Hospital , Howard County, MD 21044 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,10,14]]},"reference":[{"key":"2023101517471870700_ref1","doi-asserted-by":"crossref","first-page":"20190024","DOI":"10.1515\/pp-2019-0024","article-title":"Multicystic peritoneal mesothelioma: a systematic review of the literature","volume":"4","author":"Noiret","year":"2019","journal-title":"Pleura Peritoneum"},{"key":"2023101517471870700_ref2","doi-asserted-by":"crossref","DOI":"10.5339\/qmj.2022.5","article-title":"Benign multicystic peritoneal mesothelioma presents as a tumor in an elderly man: an uncommon diagnosis","volume":"2022","author":"Askar","year":"2022","journal-title":"Qatar Med J"},{"key":"2023101517471870700_ref3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2018\/4324986","article-title":"Benign multicystic peritoneal mesothelioma in a male patient with previous Wilms' tumor: a case report and review of the literature","volume":"2018","author":"Canu","year":"2018","journal-title":"Case Rep Surg"},{"key":"2023101517471870700_ref4","first-page":"9752908","article-title":"Benign multicystic peritoneal mesothelioma: a rare condition in an uncommon gender","volume":"2017","author":"Khurram","year":"2017","journal-title":"Case Rep Pathol"},{"key":"2023101517471870700_ref5","first-page":"222","article-title":"Benign multicystic peritoneal mesothelioma in a male teen: case report and review of the literature","volume":"39","author":"Luna-Abanto","year":"2020","journal-title":"P R Health Sci J"},{"key":"2023101517471870700_ref6","doi-asserted-by":"crossref","first-page":"5739","DOI":"10.3748\/wjg.v12.i35.5739","article-title":"Benign multicystic peritoneal mesothelioma: a case report and review of the literature","volume":"12","author":"Safioleas","year":"2006","journal-title":"World J Gastroenterol"},{"key":"2023101517471870700_ref7","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1093\/ndt\/gfp680","article-title":"Giant mesenteric cyst of mesothelial origin in a haemodialysis patient with previous peritoneal dialysis therapy","volume":"25","author":"Zeiler","year":"2010","journal-title":"Nephrol Dial Transplant"},{"volume-title":"StatPearls","year":"2023","author":"Myers","key":"2023101517471870700_ref8"},{"key":"2023101517471870700_ref9","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/jso.10081","article-title":"Malignant transformation of \u201cbenign\u201d cystic mesothelioma of the peritoneum","volume":"79","author":"Gonz\u00e1lez-Moreno","year":"2002","journal-title":"J Surg Oncol"},{"key":"2023101517471870700_ref10","doi-asserted-by":"crossref","first-page":"678","DOI":"10.3332\/ecancer.2016.678","article-title":"The first case of benign multicystic mesothelioma presenting as a splenic mass","volume":"10","author":"D'Antonio","year":"2016","journal-title":"Ecancermedicalscience"},{"key":"2023101517471870700_ref11","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1159\/000346187","article-title":"Benign cystic mesothelioma of the peritoneum: a rare case and review of the literature","volume":"5","author":"Khuri","year":"2012","journal-title":"Case Rep Oncol"},{"key":"2023101517471870700_ref12","article-title":"Benign multicystic peritoneal mesothelioma presenting as a colonic mass","volume":"13","author":"Pierre","year":"2021","journal-title":"Cureus"},{"key":"2023101517471870700_ref13","doi-asserted-by":"crossref","first-page":"e76","DOI":"10.11622\/smedj.2013085","article-title":"Multicystic peritoneal mesothelioma: not always a benign disease","volume":"54","author":"Singh","year":"2013","journal-title":"Singap Med J"},{"key":"2023101517471870700_ref14","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1177\/030089160308900107","article-title":"Peritoneal cystic mesothelioma: a case series","volume":"89","author":"Sethna","year":"2003","journal-title":"Tumori"},{"key":"2023101517471870700_ref15","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1186\/1752-1947-6-126","article-title":"Benign multicystic peritoneal mesothelioma mimicking recurrence of an ovarian borderline tumor: a case report","volume":"6","author":"Takemoto","year":"2012","journal-title":"J Med Case Rep"},{"key":"2023101517471870700_ref16","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.ejso.2010.08.130","article-title":"Multicystic peritoneal mesothelioma: outcomes and patho-biological features in a multi-institutional series treated by cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (HIPEC)","volume":"36","author":"Baratti","year":"2010","journal-title":"Eur J Surg Oncol"},{"key":"2023101517471870700_ref17","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1002\/bjs.7263","article-title":"Multi-institutional experience of diffuse intra-abdominal multicystic peritoneal mesothelioma","volume":"98","author":"Chua","year":"2011","journal-title":"Br J Surg"},{"key":"2023101517471870700_ref18","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1186\/1477-7819-10-277","article-title":"Mesothelioma as a rapidly developing giant abdominal cyst","volume":"10","author":"Vyas","year":"2012","journal-title":"World J Surg Oncol"}],"container-title":["Journal of Surgical Case 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