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Initial blood test results show a predominantly cholestatic picture with elevated tumour markers, and imaging findings are concerning for a pancreatic head neoplasm or cholangiocarcinoma with involvement of the entire common bile duct. The patient underwent staging laparoscopy and biopsies including peritoneal washing, but did not identify any features of malignancy. Immunoglobulin G and immunoglobulin G4 testing were subsequently tested and shown to be elevated. The provisional diagnosis of immunoglobulin G4-related sclerosing cholangitis was made, and steroid treatment was empirically started. Treatment with steroids was successful, with complete resolution of symptoms and abnormal imaging findings and near complete resolution of liver function test results after 1\u00a0month.<\/jats:p>","DOI":"10.1093\/jscr\/rjad621","type":"journal-article","created":{"date-parts":[[2023,11,28]],"date-time":"2023-11-28T20:15:15Z","timestamp":1701202515000},"source":"Crossref","is-referenced-by-count":2,"title":["IgG4-related sclerosing cholangitis mimicking cholangiocarcinoma"],"prefix":"10.1093","volume":"2023","author":[{"given":"Wei R","family":"Ng","sequence":"first","affiliation":[{"name":"North Canberra Hospital Department of General Surgery, , Bruce, ACT 2617 , Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ngee-Soon","family":"Lau","sequence":"additional","affiliation":[{"name":"Canberra Hospital Hepatopancreatobiliary Unit, , Garran, ACT 2605 , 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