{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T09:47:24Z","timestamp":1770284844519,"version":"3.49.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2023,11,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thyroid cancer is usually treated with surgical intervention followed by ablative radiotherapy if indicated to eliminate any metastases. Five-year survival rates are 99% for papillary thyroid carcinoma (PTC) and 82% for medullary thyroid carcinoma (MTC). The chances of survival decrease significantly with two simultaneous types of cancers and with male gender. PTC and MTC present as different entities. The coexistence of different types of thyroid carcinoma in a patient is a rare event. We report the case of a 45-year-old Saudi male with a rare synchronous occurrence of PTC in the thyroid gland, along with ectopic MTC with a unique prognosis over the years. Our case adds data to the literature supporting the coincidental coexistence of PTC and MTC.<\/jats:p>","DOI":"10.1093\/jscr\/rjad625","type":"journal-article","created":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:58:08Z","timestamp":1700614688000},"source":"Crossref","is-referenced-by-count":3,"title":["High survival simultaneous occurrence of papillary thyroid carcinoma and ectopic thyroid with medullary thyroid carcinoma; case report and literature review"],"prefix":"10.1093","volume":"2023","author":[{"given":"Saad","family":"Alshehri","sequence":"first","affiliation":[{"name":"General Surgery, King Abdulaziz Medical City , P.O. Box. 22490, Riyadh 11426 , Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faisal","family":"Alsarrani","sequence":"additional","affiliation":[{"name":"General Surgery, King Abdulaziz Medical City , P.O. Box. 22490, Riyadh 11426 , Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leenah","family":"Almanea","sequence":"additional","affiliation":[{"name":"College of Medicine, Princess Nourah Bint Abdulrahman University , P.O. Box. 84428, Riyadh 11671 , Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9016-1868","authenticated-orcid":false,"given":"Alanood","family":"Alharbi","sequence":"additional","affiliation":[{"name":"General Surgery Division, Department of Surgery, Ministry of National Guard - Health Affairs , Riyadh , Saudi Arabia"},{"name":"King Abdullah International Medical Research Center , P.O. Box 2511, Riyadh 11461 , Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2023,11,20]]},"reference":[{"key":"2023112122512056300_ref1","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.ijscr.2020.06.070","article-title":"Simultaneous occurrence of follicular and papillary thyroid carcinomas in same thyroid lobe: a case series of six patients from Qatar","volume":"73","author":"Abdelaal","year":"2020","journal-title":"Int J Surg Case Rep"},{"key":"2023112122512056300_ref2","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/s40618-016-0526-5","article-title":"Classical point mutations of RET, BRAF and RAS oncogenes are not shared in papillary and medullary thyroid cancer occurring simultaneously in the same gland","volume":"40","author":"Ciampi","year":"2017","journal-title":"J Endocrinol Invest"},{"key":"2023112122512056300_ref3","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1507\/endocrj.52.281","article-title":"Synchronous occurrence of a follicular, papillary and medullary thyroid carcinoma in a recurrent goiter","volume":"52","author":"Cupisti","year":"2005","journal-title":"Endocr J"},{"key":"2023112122512056300_ref4","doi-asserted-by":"crossref","first-page":"226","DOI":"10.15605\/jafes.034.02.16","article-title":"Simultaneous occurrence of papillary carcinoma and medullary carcinoma","volume":"34","author":"Gadong","year":"2019","journal-title":"J ASEAN Fed Endocr Soc"},{"key":"2023112122512056300_ref5","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1007\/BF03343948","article-title":"Medullary thyroid cancer, papillary thyroid microcarcinoma and Graves\u2019 disease: an unusual clinical coexistence","volume":"24","author":"Mazziotti","year":"2001","journal-title":"J Endocrinol Invest"},{"key":"2023112122512056300_ref6","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1752-1947-7-26","article-title":"Simultaneous occurrence of medullary and papillary thyroid microcarcinomas: a case series and review of the literature","volume":"7","author":"Adnan","year":"2013","journal-title":"J Med Case Rep"},{"key":"2023112122512056300_ref7","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1007\/BF03350115","article-title":"Thyroid carcinoma in thyrotoxic patients treated by surgery","volume":"11","author":"Pacini","year":"1988","journal-title":"J Endocrinol Invest"},{"key":"2023112122512056300_ref8","doi-asserted-by":"crossref","first-page":"955","DOI":"10.2169\/internalmedicine.37.955","article-title":"Mixed medullary-follicular carcinoma and papillary carcinoma of the same thyroid","volume":"37","author":"Wu","year":"1998","journal-title":"Intern Med"},{"key":"2023112122512056300_ref9","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1002\/1097-0142(19830915)52:6<1053::AID-CNCR2820520621>3.0.CO;2-Q","article-title":"A compound follicular-parafollicular cell carcinoma of the thyroid: a new tumor entity?","volume":"52","author":"Ljungberg","year":"1983","journal-title":"Cancer"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/11\/rjad625\/53612728\/rjad625.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2023\/11\/rjad625\/53612728\/rjad625.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,22]],"date-time":"2023-11-22T00:58:16Z","timestamp":1700614696000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjad625\/7434450"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,11]]},"references-count":9,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2023,11,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjad625","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2023,11]]},"published":{"date-parts":[[2023,11]]},"article-number":"rjad625"}}