{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:48Z","timestamp":1753877208161,"version":"3.41.2"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T00:00:00Z","timestamp":1708387200000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Hematometrocolpos (HMC) is a rare disorder that occurs when an anatomical anomaly like imperforate hymen causes menstrual blood to be retained in the uterus and vagina. There is no standard of care established for HMC beyond urgent vaginoplasty which requires a demanding post-operative course that may not be suited for all pediatric patients. This is a case report of successful use of image-guided percutaneous drainage of HMC with tissue plasminogen activator (TPA) followed by vaginoplasty in a 13-year-old female with lower vaginal atresia. Additionally, this case explores the role of menstrual suppression and the need for individualized guidelines. It emphasizes the potential of image-guided percutaneous drainage with TPA as a promising, less-invasive treatment option for pediatric HMC as well as the impact on follow-up surgery.<\/jats:p>","DOI":"10.1093\/jscr\/rjae006","type":"journal-article","created":{"date-parts":[[2024,2,20]],"date-time":"2024-02-20T08:35:07Z","timestamp":1708418107000},"source":"Crossref","is-referenced-by-count":1,"title":["A case of image-guided hematometrocolpos drainage requiring tissue plasminogen activator in a pediatric patient"],"prefix":"10.1093","volume":"2024","author":[{"given":"Pareena","family":"Sharma","sequence":"first","affiliation":[{"name":"Department of Medicine, Medical College of Georgia of Augusta University , 1120 15th St, Augusta, GA 30912 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jay","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Radiology, Emory School of Medicine\/Children\u2019s Healthcare of Atlanta , James B. Williams Medical Education Building 100 Woodruff Circle Atlanta, GA 30322 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nancy","family":"Sokkary","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Emory School of Medicine\/Children\u2019s Healthcare of Atlanta , James B. Williams Medical Education Building 100 Woodruff Circle Atlanta, GA 30322 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,2,19]]},"reference":[{"key":"2024032206345465200_ref1","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1007\/s00192-022-05270-x","article-title":"Hematocolpos due to imperforate hymen: a case report and literature systematic review","volume":"34","author":"Marino","year":"2023","journal-title":"Int Urogynecol J"},{"key":"2024032206345465200_ref2","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1111\/jpc.14931","article-title":"Haematocolpos due to imperforate hymen disguised as constipation","volume":"57","author":"Bonello","year":"2021","journal-title":"J Paediatr Child Health"},{"key":"2024032206345465200_ref3","doi-asserted-by":"crossref","first-page":"733","DOI":"10.1007\/s11604-021-01115-7","article-title":"Congenital anomalies causing hemato\/hydrocolpos: imaging findings, treatments, and outcomes","volume":"39","author":"Tanitame","year":"2021","journal-title":"Jpn J Radiol"},{"key":"2024032206345465200_ref4","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.jpag.2021.02.050","article-title":"46. Management of Hematocolpos in lower vaginal atresia by image-guided drainage with interventional radiology: a case series","volume":"34","author":"Williams","year":"2021","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"2024032206345465200_ref5","doi-asserted-by":"crossref","first-page":"107277","DOI":"10.1016\/j.ijscr.2022.107277","article-title":"Hematocolpos in women with uterus didelphys, imperforate hemivagina and ipsilateral renal agenesis: a case report and review of the literature","volume":"95","author":"M\u2019hamdi","year":"2022","journal-title":"Int J Surg Case Rep"},{"key":"2024032206345465200_ref6","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1016\/j.jpag.2014.12.007","article-title":"Postoperative course and complications after pull-through vaginoplasty for distal vaginal atresia","volume":"28","author":"Mansouri","year":"2015","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"2024032206345465200_ref7","doi-asserted-by":"crossref","first-page":"1853","DOI":"10.1016\/j.fertnstert.2009.09.041","article-title":"Laparoscopic drainage of hematocolpos: a new treatment option for the acute management of a transverse vaginal septum","volume":"94","author":"Dennie","year":"2010","journal-title":"Fertil Steril"},{"key":"2024032206345465200_ref8","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.jpag.2023.02.006","article-title":"Management of hematometra and hematocolpos in obstructive Mullerian anomalies by image-guided drainage with interventional radiology: a multi-institutional case series","volume":"36","author":"Childress","year":"2023","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"2024032206345465200_ref9","doi-asserted-by":"crossref","first-page":"218","DOI":"10.5811\/cpcem.2017.3.33369","article-title":"Hematometrocolpos in a pubescent girl with abdominal pain","volume":"1","author":"Kotter","year":"2017","journal-title":"Clin Pract Cases Emerg Med"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/2\/rjae006\/56969777\/rjae006.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/2\/rjae006\/56969777\/rjae006.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,22]],"date-time":"2024-03-22T06:35:12Z","timestamp":1711089312000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae006\/7610328"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":9,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae006","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,2]]},"published":{"date-parts":[[2024,2]]},"article-number":"rjae006"}}