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This case report describes a 52-year-old female with systemic sclerosis and an extensive past medical history who initially presented with complaints of worsening left lower leg pain, a negative workup for deep vein thrombosis, and an extensive palpable mass in the posterior thigh with erythema, drainage, and purulence. With multiple treatment options exhausted from her autoimmune disorders, she ultimately required surgical resection for her refractory infected calcinosis cutis. Identification of calcinosis cutis subtype in conjunction with appropriate history and physical is crucial to determining indications for treatment.<\/jats:p>","DOI":"10.1093\/jscr\/rjae068","type":"journal-article","created":{"date-parts":[[2024,2,16]],"date-time":"2024-02-16T20:47:41Z","timestamp":1708116461000},"source":"Crossref","is-referenced-by-count":4,"title":["A case report and review of calcinosis cutis"],"prefix":"10.1093","volume":"2024","author":[{"given":"Tiffany","family":"Bender","sequence":"first","affiliation":[{"name":"University of South Dakota Sanford School of Medicine , 1400 W 22nd Street, Sioux Falls, SD 57105 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Burt","sequence":"additional","affiliation":[{"name":"Department of General Surgery , , Sioux Falls, SD 57104 , United States"},{"name":"University of South Dakota Sanford School of Medicine , , Sioux Falls, SD 57104 , United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,2,13]]},"reference":[{"key":"2024022403574587300_ref1","doi-asserted-by":"crossref","first-page":"980","DOI":"10.3899\/jrheum.211393","article-title":"Management of calcinosis cutis in rheumatic diseases","volume":"49","author":"Elahamar","year":"2022","journal-title":"J Rheumatol"},{"key":"2024022403574587300_ref2","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jaad.2019.07.006","article-title":"Treatment of calcinosis cutis in systemic sclerosis and dermatomyositis: a review of the literature","volume":"82","author":"Traineau","year":"2022","journal-title":"J Am Acad Dermatol"},{"key":"2024022403574587300_ref3","volume-title":"Taylor and Kelly's Dermatology for Skin of Color","author":"McKinley","year":"2016","edition":"2nd"},{"key":"2024022403574587300_ref4","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1007\/s00403-021-02264-5","article-title":"Local, non-systemic, and minimally invasive therapies for calcinosis cutis: a systematic review","volume":"314","author":"Nowaczyk","year":"2022","journal-title":"Arch Dermatol Res"},{"key":"2024022403574587300_ref5","first-page":"455","article-title":"Calcinosis cutis occurring in association with autoimmune connective tissue disease","volume":"48","author":"Balin","year":"2022","journal-title":"JAMA Dermatol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/2\/rjae068\/56699049\/rjae068.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/2\/rjae068\/56699049\/rjae068.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,24]],"date-time":"2024-02-24T03:57:55Z","timestamp":1708747075000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae068\/7606940"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":5,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2024,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae068","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,2]]},"published":{"date-parts":[[2024,2]]},"article-number":"rjae068"}}