{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,10]],"date-time":"2026-04-10T01:14:45Z","timestamp":1775783685685,"version":"3.50.1"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T00:00:00Z","timestamp":1710460800000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Leiomyosarcoma of the prostate is a rare and aggressive tumor, with a quarter of the patients harboring metastatic disease, commonly in the lung. It usually presents with urinary obstruction in a relatively younger patient group. A 29-year-old male presented with lower urinary tract symptoms to the urologist. Computed tomography scan revealed a large pelvic mass involving the prostate. Biopsy on two occasions yielded leiomyoma. Instead of conventional radical surgery, en-bloc resection of the mass was done while preserving the remaining portion of the prostate, seminal vesicles, and ejaculatory duct. Histopathology revealed a high-grade leiomyosarcoma with negative margins. The patient had excellent recovery of defecation, erectile, and ejaculatory functions within 2\u00a0months after adjuvant radiotherapy. At the 24-month follow-up there was no evidence of disease. En-bloc resection of the tumor can be considered in select cases to improve functional outcomes and sustain a higher quality of life in patients.<\/jats:p>","DOI":"10.1093\/jscr\/rjae138","type":"journal-article","created":{"date-parts":[[2024,3,15]],"date-time":"2024-03-15T15:29:59Z","timestamp":1710516599000},"source":"Crossref","is-referenced-by-count":3,"title":["Leiomyosarcoma of the prostate: a novel approach to treatment\u2014case report and review of the literature"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4025-186X","authenticated-orcid":false,"given":"Abdul Baseet","family":"Arham","sequence":"first","affiliation":[{"name":"Department of Urology, University of Iowa , Iowa City, IA 52242 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert A","family":"Robinson","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Iowa , Iowa City, IA 52242 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammed Abou","family":"Chakra","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Iowa , Iowa City, IA 52242 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael A","family":"O\u2019Donnell","sequence":"additional","affiliation":[{"name":"Department of Urology, University of Iowa , Iowa City, IA 52242 , USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,3,15]]},"reference":[{"key":"2024031515053958000_ref1","doi-asserted-by":"crossref","first-page":"485786","DOI":"10.1155\/2015\/485786","article-title":"A review of the literature on primary leiomyosarcoma of the prostate gland","volume":"2015","author":"Venyo","year":"2015","journal-title":"Adv Urol"},{"key":"2024031515053958000_ref2","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/S0022-5347(05)65974-5","article-title":"Adult prostate sarcoma: the M. 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