{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:08:18Z","timestamp":1753877298724,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"3","license":[{"start":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T00:00:00Z","timestamp":1710806400000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,3,5]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>The omphalocele-exstrophy-imperforate anus-spinal defects (OEIS) complex is a rare birth disorder involving a combination of gastrointestinal, musculoskeletal, renal, neural, and genitourinary system defects. We present a case report of a neonate with OEIS born by vertex spontaneous delivery to non-consanguineous parents. The major presenting defect was exstrophy of the cecum lying between two exstrophied halves of the bladder, an imperforate anus and spina bifida myelomeningocele. Explorative laparotomy revealed a duplex kidney system, attachment of the terminal ileum and cecum to the exstrophy, and a sausage-like atretic large bowel. Malrotation was also noted. Ladd\u2019s bands were released followed by ileostomy and ureterostomy. Patient was stable post-operatively and in the incubator on room air. OEIS remains a challenging anomaly that requires optimal treatment to facilitate the quality of life. With appropriate surgical intervention, the functional and social treatment goals for this unusual congenital defect can be met.<\/jats:p>","DOI":"10.1093\/jscr\/rjae166","type":"journal-article","created":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T05:41:08Z","timestamp":1710826868000},"source":"Crossref","is-referenced-by-count":0,"title":["Understanding and managing a case of the omphalocele-exstrophy-imperforate anus-spinal defect complex"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0502-0938","authenticated-orcid":false,"given":"Khulud Mahmood","family":"Nurani","sequence":"first","affiliation":[{"name":"Department of Human Anatomy and Medical Physiology, University of Nairobi , PO Box 43226-80100, Nairobi , Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Waleed","family":"Abdalla","sequence":"additional","affiliation":[{"name":"Department of Surgery, Coast General Teaching and Referral Hospital , Mombasa , Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khalid Mohamed","family":"Ayub","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Nairobi West Hospital , Nairobi , Kenya"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,3,17]]},"reference":[{"key":"2024031904493190400_ref1","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jpurol.2009.09.011","article-title":"Cloacal exstrophy: a comprehensive review of an uncommon problem","volume":"6","author":"Woo","year":"2010","journal-title":"J Pediatr Urol"},{"key":"2024031904493190400_ref2","doi-asserted-by":"crossref","first-page":"104436","DOI":"10.1016\/j.amsu.2022.104436","article-title":"Prenatal diagnosis of rare cloacal exstrophy: a case report","volume":"81","author":"Febriani","year":"2022","journal-title":"Ann Med Surg"},{"key":"2024031904493190400_ref3","first-page":"41","article-title":"Complejo OEIS (onfalocele, extrofia vesical, ano imperforado y defectos espinales), una entidad m\u00e1s confusa de lo que se cree","volume":"7","author":"Mart\u00ednez C\u00f3rdoba","year":"2021","journal-title":"Reporte de caso. 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