{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T18:14:31Z","timestamp":1760552071925,"version":"3.41.2"},"reference-count":19,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2024,4,1]],"date-time":"2024-04-01T00:00:00Z","timestamp":1711929600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"UNINI"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Mesenchymal hamartoma of the liver (MHL) is rare. Less than 50 adult cases have been described. Due to their potential degeneration or recurrence, a complete surgical resection must be performed. We describe a case of a 26-year-old with a palpable solid lesion, which displaced abdominal organs. Percutaneous needle biopsies suggested the diagnosis of MHL. A right hemi-hepatectomy without segment 1 was performed; the post-operative course was uneventful. The mesenchymal component of the tumour was reactive to desmin and smooth muscle actin. Low proliferation index was confirmed (MIB1). Genetic counselling: the sequencing analysis of DICER1 and CDKN1C gene was negative, DNA methylation analysis on the chromosome 11p15 region was normal. After 42\u00a0months, there was no recurrence. In conclusion, clinicians should consider MHL in the differential diagnosis. The dimension and the need of radicality impose major liver resections or liver transplantations, which should be performed in referral centres.<\/jats:p>","DOI":"10.1093\/jscr\/rjae184","type":"journal-article","created":{"date-parts":[[2024,4,2]],"date-time":"2024-04-02T00:59:37Z","timestamp":1712019577000},"source":"Crossref","is-referenced-by-count":1,"title":["Huge mesenchymal hamartoma in a young adult: a case report"],"prefix":"10.1093","volume":"2024","author":[{"given":"Domenico","family":"Pinelli","sequence":"first","affiliation":[{"name":"Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital , Bergamo 24127 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6493-1299","authenticated-orcid":false,"given":"Claudio","family":"Guerci","sequence":"additional","affiliation":[{"name":"Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital , Bergamo 24127 , Italy"},{"name":"University of Milan , Via Festa del Perdono 7, Milano 20122 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4055-8485","authenticated-orcid":false,"given":"Francesco","family":"Cammarata","sequence":"additional","affiliation":[{"name":"Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital , Bergamo 24127 , Italy"},{"name":"University of Milan , Via Festa del Perdono 7, Milano 20122 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riccardo","family":"Cirelli","sequence":"additional","affiliation":[{"name":"Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital , Bergamo 24127 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Agnese","family":"Scatigno","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, ASST Papa Giovanni XXIII Hospital , Bergamo 24127 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Colledan","sequence":"additional","affiliation":[{"name":"Department of Organ Failure and Transplantation, ASST Papa Giovanni XXIII Hospital , Bergamo 24127 , Italy"},{"name":"School of Medicine and Surgery, Unversity of Milano-Bicocca , Milan 20126 , Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,4,1]]},"reference":[{"key":"2024040200592900400_ref1","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1007\/s00261-015-0605-7","article-title":"Prevalence of benign focal liver lesions: ultrasound investigation of 45,319 hospital patients","volume":"41","author":"Kaltenbach","year":"2016","journal-title":"Abdom Radiol"},{"key":"2024040200592900400_ref2","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1016\/j.dld.2015.09.016","article-title":"Prevalence and clinical outcome of hepatic haemangioma with specific 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