{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:34Z","timestamp":1753877194091,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T00:00:00Z","timestamp":1715731200000},"content-version":"vor","delay-in-days":14,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Thyroid fibrosarcomas represent a rare subset of tumors with exceedingly limited documented cases in the medical literature. This study delineates an unusual occurrence involving a 32-year-old female presenting with symptoms including neck pain, dysphagia, and dyspnea. Notably, the patient experienced symptom recurrence 3 months postthyroidectomy, accompanied by aggressive tumor growth. Despite the considerable size of the tumor and its infiltration into critical anatomical structures, a complex surgical intervention was executed with successful outcomes. The study underscores the imperative for further exploration into the efficacy of proposed therapeutic modalities tailored for managing this neoplasm. Moreover, it emphasizes the necessity for considering the histological classification of fibrosarcoma within the differential diagnoses spectrum for thyroid tumors.<\/jats:p>","DOI":"10.1093\/jscr\/rjae298","type":"journal-article","created":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T14:38:56Z","timestamp":1715783936000},"source":"Crossref","is-referenced-by-count":0,"title":["Primary thyroid fibrosarcoma in a 32-year-old female: case report and literature review"],"prefix":"10.1093","volume":"2024","author":[{"given":"Fouad","family":"Jaber","sequence":"first","affiliation":[{"name":"Department of Surgery , Faculty of Medicine, , Damascus 30621 , Syrian Arab Republic"},{"name":"Damascus University , Faculty of Medicine, , Damascus 30621 , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark","family":"Rahal","sequence":"additional","affiliation":[{"name":"Albasel Hospital , Department of Surgery, Homs , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amira Shikh","family":"Alkassabin","sequence":"additional","affiliation":[{"name":"Department of Surgery , Faculty of Medicine, , Damascus 30621 , Syrian Arab Republic"},{"name":"Damascus University , Faculty of Medicine, , Damascus 30621 , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hanin","family":"Hamza","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Faculty of Medicine, , Aleppo 12212 , Syrian Arab Republic"},{"name":"Aleppo University , Faculty of Medicine, , Aleppo 12212 , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salim","family":"Haddad","sequence":"additional","affiliation":[{"name":"Department of Surgery , Faculty of Medicine, , Damascus 30621 , Syrian Arab Republic"},{"name":"Damascus University , Faculty of Medicine, , Damascus 30621 , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad","family":"Shbat","sequence":"additional","affiliation":[{"name":"Department of Surgery, Assad University Hospital , Damascus , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hussain","family":"Chaban","sequence":"additional","affiliation":[{"name":"Department of Surgery, Assad University Hospital , Damascus , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zein","family":"Basha","sequence":"additional","affiliation":[{"name":"Department of Surgery, Assad University Hospital , Damascus , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sultaneh","family":"Haddad","sequence":"additional","affiliation":[{"name":"Department of Pediatrics , Faculty of Medicine, , Aleppo 12212 , Syrian Arab Republic"},{"name":"Aleppo University , Faculty of Medicine, , Aleppo 12212 , Syrian Arab Republic"},{"name":"Department of Scientific Research, Stemosis for Scientific Research , Damascus , Syrian Arab Republic"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,14]]},"reference":[{"key":"2024051513142917700_ref1","doi-asserted-by":"crossref","first-page":"172","DOI":"10.20471\/acc.2016.55.01.24","article-title":"Primary fibrosarcoma of the thyroid gland: case report","volume":"55","author":"Dabeli\u0107","year":"2016","journal-title":"Acta Clin Croat"},{"key":"2024051513142917700_ref2","first-page":"109","article-title":"Giant thyroid fibrosarcoma \u2013 a case report","volume":"32","author":"Tucciarone","year":"2020","journal-title":"Iran J Otorhinolaryngol"},{"key":"2024051513142917700_ref3","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1186\/s40792-022-01496-5","article-title":"Primary thyroid gland myxofibrosarcoma: a case report and review of the literature","volume":"8","author":"Stylianidi","year":"2022","journal-title":"Surg Case Rep"},{"key":"2024051513142917700_ref4","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1186\/1471-2407-14-899","article-title":"Prevalence and types of thyroid malignancies among thyroid enlarged patients in Gondar, Northwest Ethiopia: a three-year institution based retrospective study","volume":"14","author":"Melak","year":"2014","journal-title":"BMC Cancer"},{"key":"2024051513142917700_ref5","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1080\/00015458.2008.11680320","article-title":"Unusual malignant thyroid tumors--a clinical study of 20 cases","volume":"108","author":"Bu\u0142a","year":"2008","journal-title":"Acta Chir Belg"},{"key":"2024051513142917700_ref6","first-page":"5185","article-title":"Primary thyroid sarcoma: a systematic review","volume":"35","author":"Surov","year":"2015","journal-title":"Anticancer Res"},{"volume-title":"Fibrosarcoma","year":"2023","author":"Davis","key":"2024051513142917700_ref7"},{"key":"2024051513142917700_ref8","doi-asserted-by":"crossref","first-page":"104638","DOI":"10.18632\/oncotarget.20136","article-title":"Current diagnostics and treatment of fibrosarcoma\u2013perspectives for future therapeutic targets and strategies","volume":"8","author":"Augsburger","year":"2017","journal-title":"Oncotarget"},{"key":"2024051513142917700_ref9"},{"key":"2024051513142917700_ref10","doi-asserted-by":"crossref","first-page":"94","DOI":"10.3322\/canjclin.54.2.94","article-title":"Soft tissue sarcomas","volume":"54","author":"Cormier","year":"2004","journal-title":"CA Cancer J Clin"},{"key":"2024051513142917700_ref11","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/j.anorl.2013.09.004","article-title":"Myxofibrosarcoma of the thyroid gland","volume":"131","author":"Darouassi","year":"2014","journal-title":"Eur Ann Otorhinolaryngol Head Neck Dis"},{"key":"2024051513142917700_ref12","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1177\/000348949610501012","article-title":"Fibrosarcoma of the thyroid in a man exposed to fallout from the Chornobyl accident","volume":"105","author":"Sichel","year":"1996","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"2024051513142917700_ref13","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1002\/1097-0142(197908)44:2<584::AID-CNCR2820440227>3.0.CO;2-S","article-title":"Ultrastructure of a primary fibrosarcoma of the human thyroid gland","volume":"44","author":"Shin","year":"1979","journal-title":"Cancer"},{"key":"2024051513142917700_ref14","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1017\/S0022215100148029","article-title":"Radiation-induced fibrosarcoma of the thyroid","volume":"98","author":"Tamada","year":"1984","journal-title":"J Laryngol Otol"},{"key":"2024051513142917700_ref15","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1097\/01.coc.0000177913.82468.ba","article-title":"Synchronous fibrosarcoma and medullary thyroid cancer in a man with AIDS","volume":"29","author":"Ally","year":"2006","journal-title":"Am J Clin Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae298\/57649882\/rjae298.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae298\/57649882\/rjae298.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,15]],"date-time":"2024-05-15T14:39:06Z","timestamp":1715783946000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae298\/7672880"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae298","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,5]]},"published":{"date-parts":[[2024,5]]},"article-number":"rjae298"}}