{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:05:54Z","timestamp":1753877154908,"version":"3.41.2"},"reference-count":35,"publisher":"Oxford University Press (OUP)","issue":"5","funder":[{"name":"VA Merit Review Program","award":["I01 BX004774"],"award-info":[{"award-number":["I01 BX004774"]}]},{"name":"University of Iowa Department of Internal Medicine and Fraternal Order of Eagles Diabetes Research Center"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Esophageal diverticulum is a rare condition characterized by the herniation of the esophageal mucosa outside the esophageal wall. Here, we explore the prevalence of ED and its associated esophageal dysmotility. We also shed light on the potential impact of previous surgical interventions, such as Nissen\u2019s fundoplication, on the development of ED. This manuscript presents the case of a 72-year-old woman with a history of Nissen\u2019s fundoplication surgery who experienced worsening symptoms of dysphagia, heartburn and postprandial cough. Despite exhibiting a normal motility pattern, upper endoscopy revealed a large epiphrenic esophageal diverticulum. The patient underwent successful surgical resection with myotomy, resulting in the resolution of symptoms with no complications. This case highlights the rarity of symptomatic ED and the need to recognize it while choosing the optimal treatment modality.<\/jats:p>","DOI":"10.1093\/jscr\/rjae316","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T18:01:54Z","timestamp":1717092114000},"source":"Crossref","is-referenced-by-count":0,"title":["Atypical presentation of an epiphrenic esophageal diverticulum 20\u00a0years post fundoplication: a case report and review"],"prefix":"10.1093","volume":"2024","author":[{"given":"Dana","family":"Tasabehji","sequence":"first","affiliation":[{"name":"Division of Gastroenterology and Hepatology , Department of Internal Medicine, , Iowa City, IA 52242 , United States"},{"name":"University of Iowa Hospitals and Clinics , Department of Internal Medicine, , Iowa City, IA 52242 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2816-5689","authenticated-orcid":false,"given":"Mohammad","family":"Jarrah","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology , Department of Internal Medicine, , Iowa City, IA 52242 , United States"},{"name":"University of Iowa Hospitals and Clinics , Department of Internal Medicine, , Iowa City, IA 52242 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1402-580X","authenticated-orcid":false,"given":"Mohamad","family":"Mokadem","sequence":"additional","affiliation":[{"name":"Division of Gastroenterology and Hepatology , Department of Internal Medicine, , Iowa City, IA 52242 , United States"},{"name":"University of Iowa Hospitals and Clinics , Department of Internal Medicine, , Iowa City, IA 52242 , United States"},{"name":"Fraternal Order of Eagles Diabetes Research Center , Iowa City, IA 52242 , United States"},{"name":"Veterans Affairs Health Care System , Iowa City, IA 52242 , United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,29]]},"reference":[{"key":"2024061400413879200_ref1","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1007\/s00423-011-0843-2","article-title":"Modern pathophysiology and treatment of esophageal diverticula","volume":"397","author":"Herbella","year":"2012","journal-title":"Langenbecks Arch Surg"},{"key":"2024061400413879200_ref2","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.clinimag.2006.02.002","article-title":"Frequency and etiology of midesophageal diverticula at barium esophagography","volume":"30","author":"Hoghooghi","year":"2006","journal-title":"Clin Imaging"},{"key":"2024061400413879200_ref3","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1055\/s-2007-1005456","article-title":"Detection of subclinical disorders of the hypopharynx and larynx by gastrointestinal endoscopy","volume":"28","author":"Watanabe","year":"1996","journal-title":"Endoscopy"},{"key":"2024061400413879200_ref4","doi-asserted-by":"crossref","first-page":"759","DOI":"10.21037\/jtd-22-861","article-title":"Esophageal diverticula: from diagnosis to therapeutic management-narrative review","volume":"15","author":"Constantin","year":"2023","journal-title":"J Thorac Dis"},{"key":"2024061400413879200_ref5","doi-asserted-by":"crossref","first-page":"1447","DOI":"10.1007\/s00268-011-1065-z","article-title":"Therapeutic strategies for epiphrenic diverticula: systematic review","volume":"35","author":"Zaninotto","year":"2011","journal-title":"World J Surg"},{"key":"2024061400413879200_ref6","first-page":"606","article-title":"The surgical treatment of Pulsion diverticula of the thoracic Esophagus","volume":"129","author":"Harrington","year":"1949","journal-title":"Ann Surg"},{"key":"2024061400413879200_ref7","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1177\/000348946807700510","article-title":"Esophageal diverticula related neuromuscular problems","volume":"77","author":"Cross","year":"1968","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"2024061400413879200_ref8","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1148\/49.4.476","article-title":"Diverticula of the foregut","volume":"49","author":"Wheeler","year":"1947","journal-title":"Radiology"},{"key":"2024061400413879200_ref9","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1007\/BF02358612","article-title":"Giant epiphrenic diverticulum with achalasia occurring 20 years after Heller's operation","volume":"31","author":"Dobashi","year":"1996","journal-title":"J Gastroenterol"},{"key":"2024061400413879200_ref10","first-page":"108","article-title":"Association of midoesophageal diverticula with oesophageal motor disorders. Videofluoroscopy and manometry","volume":"38","author":"Schima","year":"1997","journal-title":"Acta radiologica Diagnosis"},{"key":"2024061400413879200_ref11","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1007\/s12262-013-0955-8","article-title":"Pulsion diverticulum of the oesophagus: more than just an out pouch","volume":"77","author":"Sonbare","year":"2015","journal-title":"Indian J Surg"},{"key":"2024061400413879200_ref12","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1007\/s11605-003-0038-4","article-title":"Management of epiphrenic diverticula","volume":"7","author":"Klaus","year":"2003","journal-title":"J Gastrointest Surg"},{"key":"2024061400413879200_ref13","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1097\/00000658-200203000-00006","article-title":"Physiologic basis for the treatment of epiphrenic diverticulum","volume":"235","author":"Nehra","year":"2002","journal-title":"Ann Surg"},{"key":"2024061400413879200_ref14","first-page":"543","article-title":"Epiphrenic esophageal diverticula: spectrum of symptoms and consequences","volume":"109","author":"Conklin","year":"2009","journal-title":"J Am Osteopath Assoc"},{"key":"2024061400413879200_ref15","doi-asserted-by":"crossref","first-page":"902","DOI":"10.1016\/j.amjsurg.2005.08.016","article-title":"Cause and treatment of epiphrenic diverticula","volume":"190","author":"Tedesco","year":"2005","journal-title":"The American Journal of Surgery"},{"key":"2024061400413879200_ref16","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1007\/s00464-008-0165-9","article-title":"Esophageal manometric characteristics and outcomes for laparoscopic esophageal diverticulectomy, myotomy, and partial fundoplication for epiphrenic diverticula","volume":"23","author":"Melman","year":"2009","journal-title":"Surg Endosc"},{"key":"2024061400413879200_ref17","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1016\/0003-4975(93)90016-B","article-title":"Epiphrenic diverticulum: results of surgical treatment","volume":"55","author":"Benacci","year":"1993","journal-title":"Ann Thorac Surg"},{"key":"2024061400413879200_ref18","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1111\/j.1442-2050.2007.00716.x","article-title":"Assessment of a pathophysiology-directed treatment for symptomatic epiphrenic diverticulum","volume":"20","author":"Reznik","year":"2007","journal-title":"Dis Esophagus"},{"key":"2024061400413879200_ref19","doi-asserted-by":"crossref","first-page":"892","DOI":"10.1002\/bjs.6652","article-title":"Lower oesophageal sphincter dysfunction is part of the functional abnormality in epiphrenic diverticulum","volume":"96","author":"D'Journo","year":"2009","journal-title":"Br J Surg"},{"key":"2024061400413879200_ref20","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1016\/j.epsc.2015.06.011","article-title":"Epiphrenic esophageal diverticulum in an adolescent with a history of a Nissen fundoplication: a case report","volume":"3","author":"Fitzgerald","year":"2015","journal-title":"Journal of Pediatric Surgery Case Reports"},{"key":"2024061400413879200_ref21","first-page":"160","article-title":"Surgical management of epiphrenic diverticula in the minimally invasive era","volume":"13","author":"Kilic","year":"2009","journal-title":"JSLS"},{"key":"2024061400413879200_ref22","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1186\/s12876-017-0649-y","article-title":"A superficial esophageal cancer in an epiphrenic diverticulum treated by endoscopic submucosal dissection","volume":"17","author":"Fu","year":"2017","journal-title":"BMC Gastroenterol"},{"key":"2024061400413879200_ref23","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/S0022-5223(19)33810-3","article-title":"Thoracic esophageal diverticula: why is operation necessary?","volume":"105","author":"Altorki","year":"1993","journal-title":"J Thorac Cardiovasc Surg"},{"key":"2024061400413879200_ref24","doi-asserted-by":"crossref","first-page":"2076","DOI":"10.1016\/j.athoracsur.2005.06.007","article-title":"Minimally invasive operation for esophageal diverticula","volume":"80","author":"Fernando","year":"2005","journal-title":"Ann Thorac Surg"},{"key":"2024061400413879200_ref25","doi-asserted-by":"crossref","first-page":"1801","DOI":"10.1016\/j.athoracsur.2007.06.057","article-title":"Surgical treatment of epiphrenic diverticula: a 30-year experience","volume":"84","author":"Varghese","year":"2007","journal-title":"Ann Thorac Surg"},{"key":"2024061400413879200_ref26","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1007\/s00104-003-0792-6","article-title":"Laparoscopic esophagotomy without diverticular resection for treating epiphrenic diverticulum in hypertonic lower esophageal sphincter","volume":"75","author":"M\u00fcller","year":"2004","journal-title":"Chirurg"},{"key":"2024061400413879200_ref27","doi-asserted-by":"crossref","first-page":"2009","DOI":"10.1007\/s11605-010-1216-9","article-title":"Epiphrenic diverticulum of the esophagus. From pathophysiology to treatment","volume":"14","author":"Soares","year":"2010","journal-title":"J Gastrointest Surg"},{"key":"2024061400413879200_ref28","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1089\/lap.2016.0365","article-title":"Surgical treatment of Epiphrenic diverticulum: technique and controversies","volume":"26","author":"Andolfi","year":"2016","journal-title":"J Laparoendosc Adv Surg Tech A"},{"key":"2024061400413879200_ref29","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1053\/j.semtcvs.2020.08.017","article-title":"Management of Epiphrenic Diverticula and Short-term Outcomes","volume":"33","author":"Sudarshan","year":"2021","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"2024061400413879200_ref30","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.amjsurg.2010.03.016","article-title":"Long-term results of minimally invasive surgery for symptomatic epiphrenic diverticulum","volume":"201","author":"Rosati","year":"2011","journal-title":"The American Journal of Surgery"},{"key":"2024061400413879200_ref31","doi-asserted-by":"crossref","first-page":"1547","DOI":"10.1007\/s00268-022-06476-2","article-title":"Treatment of achalasia and Epiphrenic diverticulum","volume":"46","author":"Nadaleto","year":"2022","journal-title":"World J Surg"},{"key":"2024061400413879200_ref32","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1007\/s12328-017-0768-6","article-title":"Distal esophageal spasm with multiple esophageal diverticula successfully treated by peroral endoscopic myotomy","volume":"10","author":"Otani","year":"2017","journal-title":"Clin J Gastroenterol"},{"key":"2024061400413879200_ref33","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1080\/00365521.2020.1745881","article-title":"S-POEM in treatment of achalasia and esophageal epiphrenic diverticula \u2013 single center experience","volume":"55","author":"Demeter","year":"2020","journal-title":"Scand J Gastroenterol"},{"key":"2024061400413879200_ref34","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1055\/a-0759-1428","article-title":"An international study on the use of peroral endoscopic myotomy (POEM) in the management of esophageal diverticula: the first multicenter D-POEM experience","volume":"51","author":"Yang","year":"2019","journal-title":"Endoscopy"},{"key":"2024061400413879200_ref35","doi-asserted-by":"crossref","first-page":"AB1092\u20133","DOI":"10.1016\/j.gie.2023.04.1672","article-title":"Efficacy of peroral endoscopic myotomy for esophageal epiphrenic divirticula: a systematic review and metaanalysis","volume":"97","author":"Zafar","year":"2023","journal-title":"Gastrointest Endosc"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae316\/58200198\/rjae316.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae316\/58200198\/rjae316.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T13:46:36Z","timestamp":1718372796000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae316\/7682463"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":35,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae316","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,5]]},"published":{"date-parts":[[2024,5]]},"article-number":"rjae316"}}