{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:04:38Z","timestamp":1753877078790,"version":"3.41.2"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T00:00:00Z","timestamp":1716076800000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Auditory processing is initiated within the primary auditory cortex, concealed within the sylvian fissure bilaterally on a collection of gyri described as Heschl\u2019s Gyrus (HG). Glial neoplasms localized to or involving HG are rare. The main symptoms of these tumours are complex partial seizures characterized by auditory features. Here, we describe an unusual case of bilateral tinnitus and hemi-paraesthesia associated with a HG diffuse astrocytoma. Bilateral tinnitus secondary to intrinsic brain tumours is atypical. Bilateral tinnitus is frequently observed in patients with noise-induced hearing loss, presbycusis, ototoxic medication, and metabolic and psychiatric disease. In the case we present, the synchronous sensory and auditory symptoms are likely due to seizure activity affecting the primary auditory and somatosensory cortex. In a patient presenting with chronic, bilateral tinnitus with no known underlying otologic disease which is associated with hemi-body paraesthesia, we would advocate for consideration of brain imaging to exclude pathology in HG.<\/jats:p>","DOI":"10.1093\/jscr\/rjae317","type":"journal-article","created":{"date-parts":[[2024,5,19]],"date-time":"2024-05-19T19:25:20Z","timestamp":1716146720000},"source":"Crossref","is-referenced-by-count":0,"title":["Bilateral tinnitus associated with a diffuse astrocytoma of Heschl\u2019s gyrus: a case report and review of literature"],"prefix":"10.1093","volume":"2024","author":[{"given":"Rabii","family":"Aboulhosn","sequence":"first","affiliation":[{"name":"School of Medicine, University of Aberdeen , Forester hill, Aberdeen AB25 2ZD , United Kingdom"},{"name":"Department of Neurosurgery, Aberdeen Royal Infirmary , Aberdeen AB25 2ZN , United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter","family":"Bodkin","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Aberdeen Royal Infirmary , Aberdeen AB25 2ZN , United Kingdom"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,18]]},"reference":[{"key":"2024051919251554200_ref1","doi-asserted-by":"crossref","first-page":"7","DOI":"10.3171\/2019.11.FOCUS19778","article-title":"Heschl\u2019s gyrus fiber intersection area: a new insight on the connectivity of the auditory-language hub","volume":"48","author":"Fern\u00e1ndez","year":"2020","journal-title":"Neurosurg Focus"},{"key":"2024051919251554200_ref2","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1093\/cercor\/3.4.313","article-title":"Topographical variation of the human primary brain cortices: implications for neuroimaging, brain mapping, and neurobiology","volume":"3","author":"Rademacher","year":"1993","journal-title":"Cereb Cortex"},{"key":"2024051919251554200_ref3","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1097\/MAO.0000000000003194","article-title":"Central processing in tinnitus: fMRI study outlining patterns of activation using an auditory discrimination task in normal versus tinnitus patients","volume":"42","author":"Zenke","year":"2021","journal-title":"Otol Neurotol"},{"key":"2024051919251554200_ref4","doi-asserted-by":"crossref","first-page":"1600","DOI":"10.1016\/S0140-6736(13)60142-7","article-title":"Tinnitus","volume":"382","author":"Baguley","year":"2013","journal-title":"Lancet"},{"key":"2024051919251554200_ref5","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1001\/jamaneurol.2022.2189","article-title":"Global prevalence and incidence of tinnitus","volume":"79","author":"Jarach","year":"2022","journal-title":"JAMA Neurol"},{"key":"2024051919251554200_ref6","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1056\/NEJMra013395","article-title":"Tinnitus","volume":"347","author":"Lockwood","year":"2002","journal-title":"N Engl J Med"},{"key":"2024051919251554200_ref7","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1007\/978-981-13-6123-4_7","article-title":"Advances in understanding, diagnosis, and treatment of tinnitus","volume":"1130","author":"Tang","year":"2019","journal-title":"Adv Exp Med Biol"},{"key":"2024051919251554200_ref8","doi-asserted-by":"crossref","first-page":"76","DOI":"10.5935\/0946-5448.20210015","article-title":"Etiology and pathophysiology of tinnitus \u2013 a systematic review","volume":"25","author":"Makar","year":"2021","journal-title":"Int Tinnitus J"},{"key":"2024051919251554200_ref9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1007\/7854_2021_238","article-title":"Neuroinflammation and tinnitus","volume":"51","author":"Shulman","year":"2021","journal-title":"Curr Top Behav Neurosci"},{"key":"2024051919251554200_ref10","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.3171\/jns.2003.98.5.1109","article-title":"Amusia following resection of a Heschls gyrus glioma","volume":"98","author":"Russel","year":"2003","journal-title":"J Neurosurg"},{"key":"2024051919251554200_ref11","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1097\/00006123-199702000-00033","article-title":"Tumours of Heschl\u2019s gyrus: report of two cases","volume":"40","author":"Silbergeld","year":"1997","journal-title":"Neurosurgery"},{"key":"2024051919251554200_ref12","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s00701-008-1495-4","article-title":"Reversible defict affecting the perception of tone of human voice after tumour resection from the right auditory cortex","volume":"150","author":"Benzagmout","year":"2008","journal-title":"Acta Neurochir"},{"key":"2024051919251554200_ref13","doi-asserted-by":"crossref","first-page":"803163","DOI":"10.3389\/fnhum.2022.803163","article-title":"The effect of right temporal lobe gliomas on left and right hemisphere neural processing during speech perception and production tasks","volume":"16","author":"Yamamoto","year":"2022","journal-title":"Front Hum Neurosci"},{"key":"2024051919251554200_ref14","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.clineuro.2014.09.007","article-title":"Low-grade temporal gliomas: surgical strategy and long-term seizure outcome","volume":"126","author":"Kemerdere","year":"2014","journal-title":"Clin Neurol Neurosurg"}],"container-title":["Journal of Surgical Case 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