{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T22:09:39Z","timestamp":1773180579273,"version":"3.50.1"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T00:00:00Z","timestamp":1716854400000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Peutz-Jeghers syndrome (PJS) is a rare genetic disorder causing gastrointestinal polyps and skin pigmentation. Our case report highlights a unique instance of jejuno-jejunal intussusception associated with PJS in a 28-year-old female patient who presented to the emergency department with colicky abdominal pain, tachycardia, and gastrointestinal symptoms. Physical examination revealed mucocutaneous hyperpigmentation. Imaging studies showed a U-shaped distension in the jejunum with thickening and pneumatosis. Laparotomy revealed a jejuno-jejunal volvulus with intussusception. Surgical resection successfully addressed gangrenous jejunal tissue and ileal polyps. Histopathology confirmed PJS polyps. Postoperatively, the patient recovered well and was discharged. Family history revealed similar skin lesions in her uncle. Our case highlights the need for prompt surgical intervention to address complications associated with PJS and elucidates a unique presentation of PJS involving jejuno-jejunal intussusception and volvulus leading to complete small bowel obstruction. We aim to deepen understanding and prompt discussions on optimal therapeutic strategies.<\/jats:p>","DOI":"10.1093\/jscr\/rjae335","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T00:26:36Z","timestamp":1716942396000},"source":"Crossref","is-referenced-by-count":1,"title":["Uncommon manifestation of Peutz-Jeghers syndrome: a case of jejuno-jejunal intussusception and volvulus leading to small bowel obstruction"],"prefix":"10.1093","volume":"2024","author":[{"given":"Hesham","family":"Barhmji","sequence":"first","affiliation":[{"name":"General Medicine Department , Faculty of Medicine, , Damascus 963 , Syria"},{"name":"Damascus University , Faculty of Medicine, , Damascus 963 , Syria"},{"name":"General Surgery Department, Maarib General Hospital Authority , Maarib 967 , Yemen"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abduraboh","family":"Alsalehi","sequence":"additional","affiliation":[{"name":"General Surgery Department, Maarib General Hospital Authority , Maarib 967 , Yemen"},{"name":"General Surgery Department, Pavol Jozef Safarik University , Kosice , Slovakia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7232-2899","authenticated-orcid":false,"given":"Ahmad","family":"Kammasha","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery , Al-Mouwasat University Hospital, Faculty of Medicine, , Damascus 963 , Syria"},{"name":"Damascus University , Al-Mouwasat University Hospital, Faculty of Medicine, , Damascus 963 , Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6479-8547","authenticated-orcid":false,"given":"Ahmad","family":"Alkheder","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology \u2013 Head and Neck Surgery , Al-Mouwasat University Hospital, Faculty of Medicine, , Damascus 963 , Syria"},{"name":"Damascus University , Al-Mouwasat University Hospital, Faculty of Medicine, , Damascus 963 , Syria"},{"name":"General Medicine Department , Faculty of Medicine, , Damascus 967 , Syria"},{"name":"Syrian Private University , Faculty of Medicine, , Damascus 967 , Syria"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,5,28]]},"reference":[{"key":"2024052900262604300_ref1","doi-asserted-by":"crossref","first-page":"e6538","DOI":"10.1097\/MD.0000000000006538","article-title":"Peutz-Jeghers syndrome with intermittent upper intestinal obstruction: a case report and review of the literature","volume":"96","author":"Duan","year":"2017","journal-title":"Medicine"},{"key":"2024052900262604300_ref2","doi-asserted-by":"crossref","first-page":"5397","DOI":"10.3748\/wjg.15.5397","article-title":"Peutz-Jeghers syndrome: diagnostic and therapeutic approach","volume":"15","author":"Kopacova","year":"2009","journal-title":"World J 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Experience with patients from the Danish Polyposis Register","volume":"9","author":"Rebsdorf Pedersen","year":"1994","journal-title":"Int J Colorectal Dis"},{"key":"2024052900262604300_ref11","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1016\/j.jcol.2014.08.012","article-title":"Diagnostic difficulty in Peutz-Jeghers syndrome","volume":"35","author":"Loureiro","year":"2015","journal-title":"J Coloproctol (Rio de Janeiro)"},{"key":"2024052900262604300_ref12","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/B978-1-4160-4686-8.50008-7","volume-title":"Early Diagnosis and Treatment of Cancer Series: Colorectal Cancer","author":"Giardiello","year":"2011"},{"key":"2024052900262604300_ref13","doi-asserted-by":"crossref","first-page":"29","DOI":"10.2174\/156652407779940404","article-title":"Gastrointestinal polyposis syndromes","volume":"7","author":"Brosens","year":"2007","journal-title":"Curr Mol Med"},{"key":"2024052900262604300_ref14","doi-asserted-by":"crossref","first-page":"101042831770513","DOI":"10.1177\/1010428317705131","article-title":"Cancer risk in patients with Peutz-Jeghers syndrome: a retrospective cohort study of 336 cases","volume":"39","author":"Chen","year":"2017","journal-title":"Tumour Biol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae335\/57946368\/rjae335.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae335\/57946368\/rjae335.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T00:26:45Z","timestamp":1716942405000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae335\/7682432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":14,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae335","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,5]]},"published":{"date-parts":[[2024,5]]},"article-number":"rjae335"}}