{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T02:15:08Z","timestamp":1790475308750,"version":"4.1.0"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T00:00:00Z","timestamp":1717027200000},"content-version":"vor","delay-in-days":29,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Postoperative management of esophagocutaneous fistulas in pediatric patients is challenging, often resulting in prolonged hospitalization and increased morbidity. Platelet-rich plasma (PRP) has emerged as a promising adjunctive treatment for such complications. We present the case of a 7-month-old infant who developed an esophago-cutaneous fistula following esophagocoloplasty for esophageal atresia type A. Despite initial conservative management, the fistula persisted, prompting the application of PRP gel derived from umbilical cord blood. After four applications of PRP, complete closure of the fistula was achieved, leading to both functional and aesthetic results. This case highlights the potential of PRP in managing refractory postoperative esophageal fistulas in pediatric patients and underscores the need for further research to optimize treatment protocols and validate its efficacy for this sort of complications<\/jats:p>","DOI":"10.1093\/jscr\/rjae350","type":"journal-article","created":{"date-parts":[[2024,5,30]],"date-time":"2024-05-30T18:01:08Z","timestamp":1717092068000},"source":"Crossref","is-referenced-by-count":5,"title":["Platelet-rich plasma therapy for postoperative esophageal fistula in a pediatric patient"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0392-579X","authenticated-orcid":false,"given":"Marco","family":"Di Mitri","sequence":"first","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greta","family":"Chiastra","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Collautti","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simone","family":"D\u2019Antonio","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marina","family":"Buzzi","sequence":"additional","affiliation":[{"name":"Emilia Romagna Cord Blood Bank , Department of Pathology, , Bologna 40138 , Italy"},{"name":"IRCCS Azienda Ospedaliero Universitaria di Bologna , Department of Pathology, , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristian","family":"Bisanti","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Annalisa","family":"Di Carmine","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Catania","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michele","family":"Libri","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tommaso","family":"Gargano","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mario","family":"Lima","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, IRCCS Azienda Ospedaliero-Universitaria di Bologna , Bologna 40138 , Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,30]]},"reference":[{"key":"2024053011524568400_ref1","doi-asserted-by":"crossref","first-page":"256","DOI":"10.5812\/ircmj.7975","article-title":"Lateral traumatic esophago-cutaneous fistula in a child; 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