{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,7]],"date-time":"2026-11-07T22:29:54Z","timestamp":1794090594672,"version":"4.8.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"5","license":[{"start":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T00:00:00Z","timestamp":1717113600000},"content-version":"vor","delay-in-days":30,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,5,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Heterotopic pregnancy (HP) is the coexistence of living or dead intrauterine pregnancy, single or multiple, and extrauterine pregnancy located in the oviduct, ovary, uterine corner, cervix or peritoneal cavity. This condition is very rare (1:30\u2009000 pregnancies). HP constitutes a rare obstetric condition. Its occurrence after natural conception is sparsely documented in the literature. Here in, we present a case of a 27-year-old primeparous women who presented at 18\u00a0weeks with features of ruptured ectopic pregnancy. Initial ultrasonographic imaging showed an intrauterine pregnancy corresponding to 18\u00a0weeks. It also revealed a floating fetus with significant collection of fluid in the pouch of Douglas, retroceacal recess and both hepatocellular recess. An emergency explorative laparotomy was done where right salpingectomy was performed. She was later followed up to term and delivered by elective cesarean section successfully. A brief narrative of the challenges in the management, clinical presentation and limitation in the management is highlighted in the present case report.<\/jats:p>\n                  <jats:p>Key message: Heterotopic pregnancy can occur in natural conception irrespective of usage of ovulation induction. Routine early pregnancy ultrasound can promote early detection with prompt surgical intervention to mitigate its complications.<\/jats:p>","DOI":"10.1093\/jscr\/rjae373","type":"journal-article","created":{"date-parts":[[2024,5,16]],"date-time":"2024-05-16T00:59:19Z","timestamp":1715821159000},"source":"Crossref","is-referenced-by-count":6,"title":["Naturally conceived heterotopic pregnancy: an atypical presentation rare case report and review of current literature"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9221-0452","authenticated-orcid":false,"given":"John","family":"Lugata","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Centre , PO Box 3010, Moshi, Tanzania"},{"name":"Faculty of Medicine, Kilimanjaro Christian Medical University College , PO Box 2240, Moshi, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baraka","family":"Shao","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Centre , PO Box 3010, Moshi, Tanzania"},{"name":"Faculty of Medicine, Kilimanjaro Christian Medical University College , PO Box 2240, Moshi, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasra","family":"Batchu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Kilimanjaro Christian Medical Centre , PO Box 3010, Moshi, Tanzania"},{"name":"Faculty of Medicine, Kilimanjaro Christian Medical University College , PO Box 2240, Moshi, Tanzania"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,5,31]]},"reference":[{"key":"2024053112115498200_ref1","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0015-0282(16)58378-2","article-title":"Heterotopic pregnancy after ovulation induction and assisted reproductive technologies: a literature review from 1971 to 1993","volume":"66","author":"Tal","year":"1996","journal-title":"Fertil Steril"},{"key":"2024053112115498200_ref2","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1067\/mob.2000.103620","article-title":"Cornual heterotopic pregnancy: contemporary management options","volume":"182","author":"Habana","year":"2000","journal-title":"Am J Obstet Gynecol"},{"key":"2024053112115498200_ref3","doi-asserted-by":"crossref","first-page":"484","DOI":"10.1093\/oxfordjournals.humrep.a137129","article-title":"Simultaneous intrauterine and ectopic pregnancies following in-vitro fertilization and gamete intra-fallopian transfer. 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A case report","volume":"53","author":"Belloni","year":"2001","journal-title":"Minerva Ginecol"},{"key":"2024053112115498200_ref10","first-page":"823","article-title":"The contralateral corpus luteum and tubal pregnancy","volume":"70","author":"Pauerstein","year":"1987","journal-title":"Obstet Gynecol"},{"key":"2024053112115498200_ref11","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.ejogrb.2014.04.046","article-title":"Management and outcome of 25 heterotopic pregnancies in Zhejiang, China","volume":"180","author":"Li","year":"2014","journal-title":"Eur J Obstet Gynecol Reprod Biol"},{"key":"2024053112115498200_ref12","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1186\/s12884-018-1777-2","article-title":"A cohort of women with ectopic pregnancy: challenges in diagnosis and management in a rural hospital in a low-income country","volume":"18","author":"Mooij","year":"2018","journal-title":"BMC Pregnancy Childbirth"},{"key":"2024053112115498200_ref13","first-page":"e6080","article-title":"Heterotopic pregnancy - a diagnostic challenge. Six case reports and literature review","volume":"11","author":"Nabi","year":"2019","journal-title":"Cureus"},{"key":"2024053112115498200_ref14","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1186\/s12884-020-03465-y","article-title":"A unique case of diagnosis of a heterotopic pregnancy at 26 weeks - case report and literature review","volume":"21","author":"Kajdy","year":"2021","journal-title":"BMC Pregnancy Childbirth"},{"key":"2024053112115498200_ref15","doi-asserted-by":"crossref","first-page":"417.e9","DOI":"10.1016\/j.fertnstert.2006.05.085","article-title":"Heterotopic pregnancy: two cases and a comparative review","volume":"87","author":"Barrenetxea","year":"2007","journal-title":"Fertil Steril"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae373\/58030426\/rjae373.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/5\/rjae373\/58030426\/rjae373.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,31]],"date-time":"2024-05-31T16:19:55Z","timestamp":1717172395000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae373\/7685760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5]]},"references-count":15,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2024,5,2]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae373","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,5]]},"published":{"date-parts":[[2024,5]]},"article-number":"rjae373"}}