{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:07Z","timestamp":1753877167605,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>A 66-year-old man presented to our institution with a positive fecal occult blood test and lower abdominal pain. Although a tumor was found in the sigmoid colon, biopsy and imaging studies failed to enable the diagnosis of the cancer, and the patient underwent surgery for treatment and diagnosis. The tumor had two distinct areas with differing features shown both histopathologically and on imaging; it was thus diagnosed as a leiomyosarcoma of the sigmoid colon with a pleomorphic component. Here, we describe a rare case of leiomyosarcoma of the sigmoid colon with a pleomorphic component. There are no reports of leiomyosarcoma with pleomorphic components arising in the colon in the literature; thus, the recurrence and metastatic characteristics are unknown. Therefore, accumulating cases in the literature may provide valuable insights into diagnosing and treating these rare tumors.<\/jats:p>","DOI":"10.1093\/jscr\/rjae454","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T12:27:46Z","timestamp":1720700866000},"source":"Crossref","is-referenced-by-count":0,"title":["A rare case of leiomyosarcoma with a pleomorphic component of the sigmoid colon"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5211-5983","authenticated-orcid":false,"given":"Takahiko","family":"Omameuda","sequence":"first","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaru","family":"Koizumi","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuzo","family":"Miyahara","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kitabayashi","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikio","family":"Shiozawa","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoru","family":"Kondo","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeo","family":"Kawai","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Pathology, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaaki","family":"Kodama","sequence":"additional","affiliation":[{"name":"Tochigi Medical Center Shimotsuga Department of Surgery, , Tochigi 329-4498, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"2024071112230074400_ref1","doi-asserted-by":"crossref","first-page":"314","DOI":"10.5152\/tjg.2014.4010","article-title":"Primary mesenchymal tumors of the colon: a report of three cases","volume":"25","author":"Yaren","year":"2014","journal-title":"Turk J Gastroenterol"},{"key":"2024071112230074400_ref2","volume-title":"Classification of Tumuors Soft tissue and Bone Tumours","author":"WHO","year":"2020","edition":"5th"},{"volume-title":"The epidemiology and pathogenesis of sarcoma. 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A very uncommon condition with poor prognosis","volume":"43","author":"Merichal Resina","year":"2020","journal-title":"Gastroenterol Hepatol"},{"key":"2024071112230074400_ref5","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1126\/science.279.5350.577","article-title":"Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors","volume":"279","author":"Hirota","year":"1998","journal-title":"Science"},{"key":"2024071112230074400_ref6","doi-asserted-by":"crossref","first-page":"437","DOI":"10.1097\/PAS.0b013e318186b158","article-title":"Monoclonal antibody DOG1. 1 shows higher sensitivity than KIT in the diagnosis of gastrointestinal stromal tumors, including unusual subtypes","volume":"33","author":"Liegl","year":"2009","journal-title":"Am J Surg Pathol"},{"key":"2024071112230074400_ref7","doi-asserted-by":"crossref","first-page":"e9923","DOI":"10.1097\/MD.0000000000009923","article-title":"Primary leiomyosarcoma in the colon: a case report","volume":"97","author":"Yang","year":"2018","journal-title":"Medicine"},{"key":"2024071112230074400_ref8","doi-asserted-by":"crossref","first-page":"1466","DOI":"10.5858\/2006-130-1466-GSTROM","article-title":"Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis","volume":"130","author":"Miettinen","year":"2006","journal-title":"Arch Pathol Lab Med"},{"key":"2024071112230074400_ref9","doi-asserted-by":"crossref","first-page":"2933","DOI":"10.1007\/s00330-002-1358-6","article-title":"Abdominal leiomyosarcomas: radiologic appearances at various locations","volume":"12","author":"Kurugoglu","year":"2002","journal-title":"Eur Radiol"},{"key":"2024071112230074400_ref10","doi-asserted-by":"crossref","first-page":"iii102","DOI":"10.1093\/annonc\/mdu254","article-title":"Soft tissue and visceral sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up","volume":"25","author":"ESMO\/European Sarcoma Network Working Group","year":"2014","journal-title":"Ann Oncol"},{"key":"2024071112230074400_ref11","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/his.12159","article-title":"Clinicopathological features of primary leiomyosarcoma of the gastrointestinal tract following recognition of gastrointestinal stromal tumours","volume":"63","author":"Yamamoto","year":"2013","journal-title":"Histopathology"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/7\/rjae454\/58503627\/rjae454.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/7\/rjae454\/58503627\/rjae454.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T12:27:56Z","timestamp":1720700876000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae454\/7710896"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":11,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae454","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,7]]},"published":{"date-parts":[[2024,7,1]]},"article-number":"rjae454"}}