{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:19:11Z","timestamp":1787498351094,"version":"build-2736575974"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T00:00:00Z","timestamp":1720656000000},"content-version":"vor","delay-in-days":10,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Rosai\u2013Dorfman disease presenting solely with intrathoracic lesions is exceptionally rare. Herein, we report the case of a 53-year-old man presenting with a posterior mediastinal tumour. Computed tomography revealed a 7-cm soft tissue shadow in the posterior mediastinum. Positron emission tomography-computed tomography demonstrated a high maximum standardized uptake value of 10.35 in the tumour, with no evidence of lymph node or other organ involvement. Serum marker levels were within the normal range. Thoracoscopic surgery was performed to obtain a biopsy for a definitive diagnosis and treatment planning. Postoperative histological findings revealed a diffuse infiltration of eosinophilic histiocytes, lymphocytes, and plasma cells. Immunohistochemical analysis indicated positivity for S-100 protein, oct-2, and cyclin D1 in these histiocytes. Consequently, the patient was diagnosed with Rosai\u2013Dorfman disease and is currently asymptomatic, undergoing regular monitoring without treatment as an outpatient. The absence of characteristic findings, such as bilateral cervical lymphadenopathy, posed challenges in preoperative diagnosis.<\/jats:p>","DOI":"10.1093\/jscr\/rjae455","type":"journal-article","created":{"date-parts":[[2024,6,29]],"date-time":"2024-06-29T09:06:01Z","timestamp":1719651961000},"source":"Crossref","is-referenced-by-count":2,"title":["Rosai\u2013Dorfman disease differentiated from a posterior mediastinal tumour: a case report"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7428-9618","authenticated-orcid":false,"given":"Yoshimitsu","family":"Hirai","sequence":"first","affiliation":[{"name":"Department of Cardiovascular and Thoracic Surgery , Wakayama Medical University, Wakayama, 641-8509, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuichi","family":"Takahashi","sequence":"additional","affiliation":[{"name":"Naga Municipal Hospital Division of Pathology, , Wakayama, Kinokawa-City, 649-6414, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Takahiro","family":"Kaki","sequence":"additional","affiliation":[{"name":"Naga Municipal Hospital Department of Respiratory Medicine, , Wakayama, Kinokawa-City, 649-6414, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aya","family":"Shima","sequence":"additional","affiliation":[{"name":"Naga Municipal Hospital Department of Breast and General Thoracic Surgery, , Wakayama, Kinokawa-City, 649-6414, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuninobu","family":"Kanai","sequence":"additional","affiliation":[{"name":"Naga Municipal Hospital Department of Respiratory Medicine, , Wakayama, Kinokawa-City, 649-6414, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryuta","family":"Iwamoto","sequence":"additional","affiliation":[{"name":"Wakayama Medical University Department of Human Pathology, , Wakayama, 641-8509, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Issei","family":"Hirai","sequence":"additional","affiliation":[{"name":"Naga Municipal Hospital Department of Breast and General Thoracic Surgery, , Wakayama, Kinokawa-City, 649-6414, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,7,11]]},"reference":[{"key":"2024071112294080100_ref1","first-page":"63","article-title":"Sinus histiocytosis with massive lymphadenopathy. A newly recognized benign clinicopathological entity","volume":"87","author":"Rosai","year":"1969","journal-title":"Arch Pathol"},{"key":"2024071112294080100_ref2","doi-asserted-by":"crossref","first-page":"2877","DOI":"10.1182\/blood-2018-03-839753","article-title":"Consensus recommendations for the diagnosis and clinical management of Rosai-Dorfman-Destombes disease","volume":"131","author":"Abla","year":"2018","journal-title":"Blood"},{"key":"2024071112294080100_ref3","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1620\/tjem.227.231","article-title":"Intrathoracic Rosai-Dorfman disease with spontaneous remission: a clinical report and a review of the literature","volume":"227","author":"Noguchi","year":"2012","journal-title":"Tohoku J Exp Med"},{"key":"2024071112294080100_ref4","first-page":"3187","article-title":"Infantile Rosai-Dorfman disease: an unusual case of neck swelling and a literature review","volume":"13","author":"Liu","year":"2020","journal-title":"Int J Clin Exp Pathol"},{"key":"2024071112294080100_ref5","doi-asserted-by":"crossref","first-page":"348","DOI":"10.3324\/haematol.2019.219626","article-title":"Clinicopathological features, treatment approaches, and outcomes in Rosai-Dorfman disease","volume":"105","author":"Goyal","year":"2020","journal-title":"Haematologica"},{"key":"2024071112294080100_ref6","doi-asserted-by":"crossref","first-page":"709","DOI":"10.1016\/j.clml.2019.06.013","article-title":"Rosai-Dorfman disease: the MD Anderson Cancer Center experience","volume":"19","author":"Sathyanarayanan","year":"2019","journal-title":"Clin Lymphoma Myeloma Leuk"},{"key":"2024071112294080100_ref7","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1111\/j.1440-1827.2009.02362.x","article-title":"Rosai-Dorfman disease presenting as a solitary mediastinal mass","volume":"59","author":"Hida","year":"2009","journal-title":"Pathol Int"},{"key":"2024071112294080100_ref8","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1093\/ajcp\/aqac119","article-title":"Strong coexpression of transcription factors PU.1 and Oct-2 in Rosai-Dorfman disease","volume":"158","author":"Kiruthiga","year":"2022","journal-title":"Am J Clin Pathol"},{"key":"2024071112294080100_ref9","doi-asserted-by":"crossref","first-page":"312","DOI":"10.5581\/1516-8484.20110083","article-title":"Rosai-Dorfman disease with spontaneous resolution: case report of a child","volume":"33","author":"Lima","year":"2011","journal-title":"Rev Bras Hematol Hemoter"},{"key":"2024071112294080100_ref10","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1177\/107327481402100408","article-title":"Rosai-Dorfman disease: tumor biology, clinical features, pathology, and treatment","volume":"21","author":"Dalia","year":"2014","journal-title":"Cancer Control"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/7\/rjae455\/58503601\/rjae455.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/7\/rjae455\/58503601\/rjae455.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T08:33:34Z","timestamp":1720686814000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae455\/7710892"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,1]]},"references-count":10,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae455","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2024,7]]},"published":{"date-parts":[[2024,7,1]]},"article-number":"rjae455"}}