{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:51Z","timestamp":1753877211838,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,4]],"date-time":"2024-09-04T00:00:00Z","timestamp":1725408000000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Necrotizing otitis externa (NOE) is a severe infection primarily affecting the external auditory canal, seen mainly in immunocompromised individuals as patients with diabetes mellitus (DM). This case report highlights unusual complications of NOE: temporal bone and nasopharyngeal abscesses. These complications underscore the severity of NOE, particularly when caused by rare pathogens such as Klebsiella species. We detail the case of a 70-year-old male with uncontrolled DM who presented with severe right ear pain, purulent discharge, and significant postauricular swelling. Laboratory investigations revealed elevated inflammatory markers and poorly controlled diabetes. Cultures confirmed Klebsiella pneumoniae, and imaging showed diffuse edema and abscess formation in the temporal bone and nasopharynx. The patient was treated with intravenous Ceftazidime and ciprofloxacin for 6 weeks, followed by oral ciprofloxacin. Effective management of NOE necessitates a comprehensive, multidisciplinary approach. Early intervention, regular monitoring, and imaging are critical for promptly detecting and managing complications.<\/jats:p>","DOI":"10.1093\/jscr\/rjae565","type":"journal-article","created":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T18:57:37Z","timestamp":1725562657000},"source":"Crossref","is-referenced-by-count":0,"title":["Nasopharyngeal and temporal bone abscess following necrotizing otitis externa: a case report"],"prefix":"10.1093","volume":"2024","author":[{"given":"Ahmad S","family":"Alharthi","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head & Neck Surgery, Alhada Armed Forces Hospital , Alhada, Taif City 26792, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-1981-2171","authenticated-orcid":false,"given":"Zohour A","family":"Almalki","sequence":"additional","affiliation":[{"name":"College of Medicine and Surgery, Taif University , Alhawiyah, Taif City 26516, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johara A","family":"Alnafie","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head & Neck Surgery, King Abdullah Medical City , Muzdalifah road, Makkah City 24247, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hazem K","family":"Althobaiti","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head & Neck Surgery, Alhada Armed Forces Hospital , Alhada, Taif City 26792, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed M","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head & Neck Surgery, Alhada Armed Forces Hospital , Alhada, Taif City 26792, Saudi Arabia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,9,5]]},"reference":[{"key":"2024090423171329300_ref1","article-title":"Malignant otitis externa: An updated review","volume":"42","author":"","journal-title":"Am J Otolaryngol"},{"key":"2024090423171329300_ref2","doi-asserted-by":"crossref","first-page":"562","DOI":"10.12659\/AJCR.913469","article-title":"Fungal malignant otitis externa involves a cascade of complications culminating in pseudoaneurysm of internal maxillary artery: a case report","volume":"20","author":"Chaudhary","year":"2019","journal-title":"Am J Case Rep"},{"key":"2024090423171329300_ref3","doi-asserted-by":"crossref","first-page":"228","DOI":"10.21053\/ceo.2016.00612","article-title":"Analysis of prognostic factors in malignant external otitis","volume":"10","author":"Lee","year":"2017","journal-title":"Clin Exp Otorhinolaryngol"},{"key":"2024090423171329300_ref4","doi-asserted-by":"crossref","first-page":"1559325820963910","DOI":"10.1177\/1559325820963910","article-title":"From uncommon infection to multi-cranial palsy: malignant external otitis insights","volume":"18","author":"Ferlito","year":"2020","journal-title":"Dose Response"},{"key":"2024090423171329300_ref5","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1016\/j.amjoto.2016.04.005","article-title":"Malignant external otitis: factors predicting patient outcomes","volume":"37","author":"Stern Shavit","year":"2016","journal-title":"Am J Otolaryngol"},{"key":"2024090423171329300_ref6","article-title":"Changing trend in the antibiotic resistance pattern of Klebsiella pneumonia isolated from endotracheal aspirate samples of ICU patients of a tertiary Care Hospital in North India","volume":"15","author":"Sharma","year":"2023","journal-title":"Cureus"},{"key":"2024090423171329300_ref7","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1017\/S002221511500105X","article-title":"Necrotising (malignant) otitis externa in the UK: a growing problem. Review of five cases and analysis of national hospital episode statistics trends","volume":"129","author":"Chawdhary","year":"2017","journal-title":"J Laryngol Otol"},{"key":"2024090423171329300_ref8","doi-asserted-by":"crossref","first-page":"1004","DOI":"10.1097\/MAO.0000000000002723","article-title":"Necrotizing otitis externa: a systematic review and analysis of changing trends","volume":"41","author":"Byun","year":"2020","journal-title":"Otol Neurotol"},{"key":"2024090423171329300_ref9","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1177\/0003489419846143","article-title":"Effective inexpensive management of necrotizing otitis externa is possible in resource-poor settings","volume":"128","author":"Honnurappa","year":"2019","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"2024090423171329300_ref10","first-page":"9e14","article-title":"Changing trends in the management of malignant otitis externa: our experience","volume":"7","author":"Karthik Shamanna","year":"2018","journal-title":"Res Otolaryngol"},{"key":"2024090423171329300_ref11","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1007\/s00405-005-0998-y","article-title":"Necrotizing external otitis in a patient caused by Klebsiella pneumoniae","volume":"263","author":"Yang","year":"2006","journal-title":"Eur Arch Otorhinolaryngol"},{"key":"2024090423171329300_ref12","article-title":"Klebsiella pneumoniae-induced multiple invasive abscesses: a case report and literature review","volume":"98","author":"Wang","year":"2019","journal-title":"Medicine (Baltimore)"},{"article-title":"Necrotizing otitis externa: a systematic review","volume-title":"Otol Neurotol","author":"","key":"2024090423171329300_ref13"},{"key":"2024090423171329300_ref14","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/j.otc.2008.01.004","article-title":"Malignant otitis externa","volume":"41","author":"Carfrae","year":"2008","journal-title":"Otolaryngol Clin"},{"key":"2024090423171329300_ref15","doi-asserted-by":"crossref","first-page":"549","DOI":"10.1007\/s12070-018-1426-0","article-title":"The role of surgical debridement in cases of refractory malignant otitis externa","volume":"70","author":"Singh","year":"2018","journal-title":"Indian J Otolaryngol Head Neck Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/9\/rjae565\/59021504\/rjae565.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/9\/rjae565\/59021504\/rjae565.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T18:57:43Z","timestamp":1725562663000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae565\/7749483"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":15,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae565","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,9]]},"article-number":"rjae565"}}