{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:52Z","timestamp":1753877212940,"version":"3.41.2"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T00:00:00Z","timestamp":1727049600000},"content-version":"vor","delay-in-days":22,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Low mucinous neoplasm of the appendix (LAMN) and appendiceal diverticulum are both uncommon pathologies that may pose a diagnostic challenge. Both may present as either appendicitis or asymptomatically and have a risk of perforation. LAMN, carries the additional risk of pseudomyxoma pertitonei and metastasis. Ensuring correct histopathology is crucial, as computed tomography (CT) abdomen\/pelvis may only demonstrate a mildly dilated appendix, delaying diagnostic laparoscopy and appendicectomy. Here, we describe the case report of a 56-year-old woman who presented with chronic intermittent right iliac fossa pain initially determined to be chronic appendicitis. Following laparoscopic appendicectomy, histopathology demonstrated LAMN, however, on further re- assessment of histopathology, as well as the completion of a normal pan-CT and colonoscopy, a final diagnosis of ruptured appendiceal diverticulum was made. Our case demonstrates the utility of a multi-disciplinary approach in evaluating patients with possible appendiceal LAMN or appendiceal diverticulum.<\/jats:p>","DOI":"10.1093\/jscr\/rjae586","type":"journal-article","created":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T17:56:28Z","timestamp":1727114188000},"source":"Crossref","is-referenced-by-count":0,"title":["Differentiating appendiceal neoplasm from perforated appendiceal diverticulum in chronic appendicitis: a case report"],"prefix":"10.1093","volume":"2024","author":[{"given":"Tracey","family":"Edwards","sequence":"first","affiliation":[{"name":"Department of Surgery, Shoalhaven District Memorial Hospital , Illawarra Shoalhaven Local Health District, Nowra 2541, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1681-8583","authenticated-orcid":false,"given":"Phelopatir","family":"Anthony","sequence":"additional","affiliation":[{"name":"Department of Surgery, Shoalhaven District Memorial Hospital , Illawarra Shoalhaven Local Health District, Nowra 2541, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagy","family":"Andrawis","sequence":"additional","affiliation":[{"name":"Department of Surgery, Shoalhaven District Memorial Hospital , Illawarra Shoalhaven Local Health District, Nowra 2541, Australia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,9,23]]},"reference":[{"key":"2024092317562064100_ref1","doi-asserted-by":"publisher","first-page":"961","DOI":"10.1016\/j.ijscr.2014.10.066","article-title":"Appendiceal diverticulum associated with chronic appendicitis","volume":"5","author":"Zubieta-O\u2019Farrill","year":"2014","journal-title":"Int J Surg Case Rep"},{"key":"2024092317562064100_ref2","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1177\/1066896909332728","article-title":"Diverticulosis and diverticulitis of the appendix","volume":"17","author":"AbdullGaffar","year":"2009","journal-title":"Int J Surg Pathol"},{"key":"2024092317562064100_ref3","doi-asserted-by":"publisher","first-page":"1871","DOI":"10.1111\/ans.15811","article-title":"Systematic review and meta-analysis of the association between diverticulosis of the appendix and neoplasia","volume":"90","author":"Lim","year":"2020","journal-title":"ANZ J Surg"},{"key":"2024092317562064100_ref4","doi-asserted-by":"publisher","first-page":"3615","DOI":"10.1007\/s00423-022-02639-w","article-title":"Low-grade mucinous neoplasms (LAMN) of the appendix in Germany between 2011 and 2018: a nationwide analysis based on data provided by the German Center for Cancer Registry Data (ZfKD) at the Robert Koch institute (RKI)","volume":"407","author":"K\u00f6hler","year":"2022","journal-title":"Langenbecks Arch Surg"},{"key":"2024092317562064100_ref5","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1016\/j.humpath.2022.07.004","article-title":"Staging of appendiceal mucinous neoplasms: challenges and recent updates","volume":"132","author":"Umetsu","year":"2023","journal-title":"Hum Pathol"},{"key":"2024092317562064100_ref6","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.906344","article-title":"Case report: an unusual case of pulmonary metastatic adenocarcinoma from low-grade appendiceal mucinous neoplasms","volume":"12","author":"Zhao","year":"2022","journal-title":"Front Oncol"},{"key":"2024092317562064100_ref7","doi-asserted-by":"publisher","first-page":"105636","DOI":"10.1016\/j.ijscr.2021.02.022","article-title":"Emergency laparoscopic ileocecal resection for a low-grade appendiceal mucinous neoplasm with impending rupture: a case report","volume":"80","author":"Kitagawa","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"2024092317562064100_ref8","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1200\/EDBK_321009","volume-title":"Current Management of Appendiceal Neoplasms. American Society of Clinical Oncology Educational Book","author":"Hoehn","year":"2021"},{"key":"2024092317562064100_ref9","doi-asserted-by":"publisher","first-page":"1","DOI":"10.12659\/AJCR.934838","article-title":"Acute perforated appendicitis associated with appendiceal diverticulitis in a young man: a case report with literature review","volume":"23","author":"Abdulmomen","year":"2022","journal-title":"Am J Case Rep"},{"key":"2024092317562064100_ref10","doi-asserted-by":"publisher","first-page":"e7","DOI":"10.1016\/j.amjmed.2012.05.032","article-title":"Chronic appendicitis: an often forgotten cause of recurrent abdominal pain","volume":"126","author":"Shah","year":"2013","journal-title":"Am J Med"},{"key":"2024092317562064100_ref11","doi-asserted-by":"publisher","first-page":"1107","DOI":"10.1634\/theoncologist.2017-0081","article-title":"Appendiceal mucinous neoplasms: diagnosis and management","volume":"22","author":"Shaib","year":"2017","journal-title":"Oncologist"},{"key":"2024092317562064100_ref12","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/s12893-021-01091-9","article-title":"A retrospective analysis and literature review of neoplastic appendiceal mucinous lesions","volume":"21","author":"Matias-Garc\u00eda","year":"2021","journal-title":"BMC Surg"},{"key":"2024092317562064100_ref13","doi-asserted-by":"publisher","first-page":"1569","DOI":"10.1007\/s00384-018-3086-7","article-title":"Clinical significance of appendiceal diverticulum: a significant marker for appendiceal neoplasia in Australian patients","volume":"33","author":"Chan","year":"2018","journal-title":"Int J Colorectal Dis"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/9\/rjae586\/59242784\/rjae586.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/9\/rjae586\/59242784\/rjae586.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,23]],"date-time":"2024-09-23T17:56:29Z","timestamp":1727114189000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae586\/7765471"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9]]},"references-count":13,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae586","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,9]]},"published":{"date-parts":[[2024,9]]},"article-number":"rjae586"}}