{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:02Z","timestamp":1753877222300,"version":"3.41.2"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"11","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Pulmonary hypertension is a known perioperative risk factor that carries a high morbidity and mortality rate. Severe pulmonary hypertension is related to high morbidity after general anaesthesia. We are reporting three patients with underlying severe pulmonary hypertension, who presented with intestinal obstruction managed with different perioperative approaches. In case 1, a 38-year-old man with Eisenmenger syndrome and severe pulmonary hypertension underwent exploratory laparotomy, right hemicolectomy, and double barrel stoma for obstructed right-sided colonic tumour. He passed away on Day 6 post-operation. In case 2, a 52-year-old man with Eisenmenger syndrome and severe pulmonary hypertension presented with obstructed rectosigmoid tumour and jejunojejunal intussusception and underwent exploratory laparotomy and Hartmann\u2019s procedure. He succumbed after 33\u00a0days of fighting with cardiovascular and respiratory complications. In case 3, a 65-year-old woman, with strangulated paraumbilical hernia, underwent mini laparotomy, small bowel resection, primary anastomosis, and paraumbilical hernia repair under monitored sedation and local anaesthesia. She was discharged home after 7 days of hospitalization.<\/jats:p>","DOI":"10.1093\/jscr\/rjae711","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T02:22:57Z","timestamp":1732069377000},"source":"Crossref","is-referenced-by-count":0,"title":["Operative strategies and outcomes for patients with severe pulmonary artery hypertension and intestinal obstruction: case series from single institution\u2014sharing lessons to improve surgical outcomes"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0990-5060","authenticated-orcid":false,"given":"Khairunnisa Che","family":"Ghazali","sequence":"first","affiliation":[{"name":"Department of Surgery, Hospital Raja Perempuan Zainab II , 15586 Kota Bharu, Kelantan ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8397-473X","authenticated-orcid":false,"given":"Ann Dasimakamalia","family":"Mat","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Raja Perempuan Zainab II , 15586 Kota Bharu, Kelantan ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-2681-9640","authenticated-orcid":false,"given":"Huzairi","family":"Yaacob","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Raja Perempuan Zainab II , 15586 Kota Bharu, Kelantan ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Urfi Omar","family":"Hamdan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Raja Perempuan Zainab II , 15586 Kota Bharu, Kelantan ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmad Shanwani Mohamed","family":"Sidek","sequence":"additional","affiliation":[{"name":"Department of Surgery, Hospital Raja Perempuan Zainab II , 15586 Kota Bharu, Kelantan ,","place":["Malaysia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,11,19]]},"reference":[{"key":"2024112002473265900_ref1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9051456","article-title":"Pulmonary hypertension in adults with congenital heart disease: real-world data from the international compera-chd registry","volume":"9","author":"Kaemmerer","year":"2020","journal-title":"J Clin Med"},{"key":"2024112002473265900_ref2","doi-asserted-by":"publisher","first-page":"1190","DOI":"10.21037\/cdt-21-135","article-title":"Treatment of adults with Eisenmenger syndrome-state of the art in the 21st century: a short overview","volume":"11","author":"Diller","year":"2021","journal-title":"Cardiovasc Diagn Therapy"},{"key":"2024112002473265900_ref3","doi-asserted-by":"publisher","first-page":"1691","DOI":"10.1016\/j.jacc.2005.02.055","article-title":"Impact of pulmonary hypertension on the outcomes of noncardiac surgery: predictors of perioperative morbidity and mortality","volume":"45","author":"Ramakrishna","year":"2005","journal-title":"J Am Coll Cardiol"},{"key":"2024112002473265900_ref4","doi-asserted-by":"publisher","first-page":"222","DOI":"10.1016\/S0735-1097(98)00554-3","article-title":"Noncardiac surgery in Eisenmenger syndrome","volume":"33","author":"Ammash","year":"1999","journal-title":"J Am Coll Cardiol"},{"key":"2024112002473265900_ref5","doi-asserted-by":"publisher","first-page":"1638","DOI":"10.1136\/heartjnl-2020-316665","volume-title":"Eisenmenger Syndrome: Diagnosis, Prognosis and Clinical Management","author":"Arvanitaki","year":"2020"},{"key":"2024112002473265900_ref6","doi-asserted-by":"publisher","first-page":"105906","DOI":"10.1016\/j.ijscr.2021.105906","article-title":"A case of sigmoidectomy for sigmoid colon cancer with severe pulmonary arterial hypertension associated with mixed tissue connected disease: a case report","volume":"83","author":"Takagi","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"2024112002473265900_ref7","doi-asserted-by":"publisher","first-page":"e1","DOI":"10.1016\/j.clinre.2017.04.003","article-title":"Marked edema of colonic stoma after colectomy and severe pulmonary hypertension: report of two cases","volume":"42","author":"Hojo","year":"2018","journal-title":"Clin Res Hepatol Gastroenterol"},{"key":"2024112002473265900_ref8","doi-asserted-by":"publisher","first-page":"774","DOI":"10.1016\/j.bja.2021.01.005","article-title":"Perioperative management of patients with pulmonary hypertension undergoing non-cardiothoracic, non-obstetric surgery: a systematic review and expert consensus statement","volume":"126","author":"Price","year":"2021","journal-title":"Br J Anaesth"}],"container-title":["Journal of Surgical Case 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