{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,24]],"date-time":"2025-08-24T23:02:09Z","timestamp":1756076529702,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T00:00:00Z","timestamp":1734393600000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ganglioneuromas (GN) are tumours of ectodermal origin, derived from the neural crest cells. Appendiceal GN are extremely rare, with only eight contemporary case reports in the literature. Being benign and indolent, the necessity of resection for GNs is often debated. However, obtaining tissue to confirm the diagnosis can be challenging, frequently leading to surgical resection. We present a case of an 85-year-old male with an enlarging appendiceal nodule diagnosed endoscopically. Further investigation with computed tomography (CT) scan failed to define the pathology. A laparoscopic appendicectomy was performed, which confirmed the diagnosis of appendiceal GN.<\/jats:p>","DOI":"10.1093\/jscr\/rjae735","type":"journal-article","created":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T04:05:44Z","timestamp":1734408344000},"source":"Crossref","is-referenced-by-count":1,"title":["Ganglioneuroma: a rare appendiceal tumour \u2013 case report and literature review"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6731-6101","authenticated-orcid":false,"given":"Rakesh","family":"Quinn","sequence":"first","affiliation":[{"name":"Department of Colorectal Surgery, Nepean Hospital , Derby St, Kingswood, NSW, 2747 ,","place":["Australia"]},{"name":"University of Sydney , Sydney Medical School, Faculty of Medicine and Health, NSW ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jodie","family":"Ellis-Clark","sequence":"additional","affiliation":[{"name":"Department of Colorectal Surgery, Nepean Hospital , Derby St, Kingswood, NSW, 2747 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"2024121704053439800_ref1","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1002\/bjs.5385","article-title":"Management of an unexpected appendiceal neoplasm","volume":"93","author":"Murphy","year":"2006","journal-title":"Br J Surg"},{"key":"2024121704053439800_ref2","first-page":"365","article-title":"71,000 human appendix specimens","volume":"14","author":"Collins","year":"1963","journal-title":"Am J Proctol"},{"key":"2024121704053439800_ref3","doi-asserted-by":"publisher","first-page":"12","DOI":"10.1111\/cen.14297","article-title":"Ganglioneuromas across age groups: systematic review of individual patient data","volume":"94","author":"Fliedner","year":"2021","journal-title":"Clin Endocrinol (Oxf)"},{"key":"2024121704053439800_ref4","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1097\/SLA.0000000000005625","article-title":"Retrospective analysis of retroperitoneal-abdominal-pelvic ganglioneuromas: an international study by the transatlantic Australasian retroperitoneal sarcoma working group (TARPSWG)","volume":"278","author":"Noh","year":"2023","journal-title":"Ann Surg"},{"key":"2024121704053439800_ref10","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.epsc.2016.05.009","article-title":"Multifocal appendiceal ganglioneuroma as the presenting symptom in a patient with PTEN hamartoma syndrome","volume":"11","author":"Gonzalez","year":"2016","journal-title":"J Pediatr Surg Case Rep"},{"key":"2024121704053439800_ref5","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1055\/s-0030-1263195","article-title":"Morbidity after ganglioneuroma excision: is surgery necessary?","volume":"21","author":"Retrosi","year":"2011","journal-title":"Eur J Pediatr Surg"},{"key":"2024121704053439800_ref6","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1055\/s-0033-1358790","article-title":"Ganglioneuroma: to operate or not to operate","volume":"24","author":"Sanchez-Galan","year":"2014","journal-title":"Eur J Pediatr Surg"},{"key":"2024121704053439800_ref7","doi-asserted-by":"publisher","first-page":"1143","DOI":"10.1016\/S0046-8177(82)80256-6","article-title":"Ganglioneuroma causing acute appendicitis","volume":"13","author":"Zarabi","year":"1982","journal-title":"Hum Pathol"},{"key":"2024121704053439800_ref8","first-page":"127","article-title":"Giant appendix with diffuse ganglioneuromatosis. An unusual presentation of von recklinghausen's disease","volume":"158","author":"Lie","year":"1992","journal-title":"Eur J Surg"},{"key":"2024121704053439800_ref9","doi-asserted-by":"publisher","first-page":"132","DOI":"10.2214\/ajr.175.1.1750132","article-title":"Appendiceal ganglioneuromas and pheochromocytoma in neurofibromatosis type 1","volume":"175","author":"Lockhart","year":"2000","journal-title":"AJR"},{"key":"2024121704053439800_ref11","doi-asserted-by":"publisher","first-page":"22","DOI":"10.1016\/j.clinimag.2017.05.018","article-title":"Appendiceal ganglioneuroma in neurofibromatosis type 2","volume":"45","author":"Esterson","year":"2017","journal-title":"Clin Imaging"},{"key":"2024121704053439800_ref12","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1186\/s40792-021-01299-0","article-title":"A case of appendiceal ganglioneuroma in neurofibromatosis type 1","volume":"7","author":"Shimizu","year":"2021","journal-title":"Surg Case Rep"},{"key":"2024121704053439800_ref13","doi-asserted-by":"publisher","first-page":"rjab632","DOI":"10.1093\/jscr\/rjab632","article-title":"Appendicitis and ganglioneuroma-an unusual co-existence","volume":"2022","author":"Koullouros","year":"2022","journal-title":"J Surg Case Rep"},{"key":"2024121704053439800_ref14","doi-asserted-by":"publisher","first-page":"rjae019","DOI":"10.1093\/jscr\/rjae019","article-title":"Appendiceal ganglioneuroma incidentally found during resection of recurrent rectal cancer: case report and review of the literature","volume":"2024","author":"Perez Pachon","year":"2024","journal-title":"J Surg Case Rep"},{"key":"2024121704053439800_ref15","doi-asserted-by":"publisher","DOI":"10.3390\/cancers16050866","article-title":"Current status of treatment among patients with appendiceal tumors-old challenges and new solutions?","volume":"16","author":"Chawrylak","year":"2024","journal-title":"Cancers (Basel)"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/12\/rjae735\/61193359\/rjae735.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/12\/rjae735\/61193359\/rjae735.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,17]],"date-time":"2024-12-17T04:05:54Z","timestamp":1734408354000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae735\/7924920"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,1]]},"references-count":15,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae735","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,12]]},"published":{"date-parts":[[2024,12,1]]},"article-number":"rjae735"}}