{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:05Z","timestamp":1753877225490,"version":"3.41.2"},"reference-count":18,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Chronic granulomatous invasive fungal rhinosinusitis (CGIFRS) is a type of invasive fungal rhinosinusitis that is characterized by the presence of pathologic findings of non-caseating granulomas in the paranasal sinuses. This article describes two cases of CGIFRS with fatal outcomes. The first case was for a 36-year-old man who presented with headache, dizziness, and vomiting for 1\u00a0month. This patient had received the traditional treatment, although the patient\u2019s condition suddenly deteriorated after 1\u00a0week of surgery and died due to the disease\u2019s complications. Similarly, the second case was for a 31-year-old man who presented with bilateral nasal obstruction and left eye proptosis for 1\u00a0year. This patient had a recurrence of CGIFRS after the first presentation, which was complicated by a cerebral abscess after 2\u00a0months of surgery. This study, therefore, underscores the severity of CGIFRS as a potentially fatal disease.<\/jats:p>","DOI":"10.1093\/jscr\/rjae770","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T13:23:27Z","timestamp":1734009807000},"source":"Crossref","is-referenced-by-count":0,"title":["Mortality patterns in chronic granulomatous invasive fungal rhinosinusitis: insights from two fatal cases"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6737-7652","authenticated-orcid":false,"given":"Hussain J","family":"Aljubran","sequence":"first","affiliation":[{"name":"College of Medicine, Imam Abdulrahman Bin Faisal University , Dammam 43221 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar A","family":"Bamalan","sequence":"additional","affiliation":[{"name":"Department of Surgery, Security Forces Hospital , Dammam 43221 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria R","family":"Alabdulaal","sequence":"additional","affiliation":[{"name":"College of Medicine, Arabian Gulf University , Manama 973 ,","place":["Bahrain"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fadhel","family":"Almolani","sequence":"additional","affiliation":[{"name":"Department of Radiology, King Fahad Specialist Hospital , Dammam 32253 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad S","family":"Alahmari","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, King Fahad Specialist Hospital , Dammam 32253 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulrahman","family":"Alkhatib","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, King Fahad Specialist Hospital , Dammam 32253 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