{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:06Z","timestamp":1753877226273,"version":"3.41.2"},"reference-count":22,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T00:00:00Z","timestamp":1733961600000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Acute appendicitis and acute cholecystitis are among the commonest pathologies in acute general surgery. They are characterized by distinct symptoms, clinical examination findings and typical elements of the history which direct further investigations. In the absence of these classic findings, these diagnoses can be missed, particularly where they occur synchronously. Here we present the interesting case of a 63-year-old male who presented to the emergency department with epigastric pain and vomiting with no classical appendicitis or cholecystitis findings who was found to have both appendicitis with a 3\u00a0cm collection and gangrenous cholecystitis, managed with urgent laparoscopic appendicectomy and cholecystectomy. This patient had a background of Type 2 Diabetes which may have reduced awareness of symptoms. Given the increasing prevalence of Type 2 Diabetes and the risk of rapid deterioration in these patients, this case demonstrates the importance of prompt assessment of the entire abdomen when these patients present with acute abdomen.<\/jats:p>","DOI":"10.1093\/jscr\/rjae785","type":"journal-article","created":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T13:38:31Z","timestamp":1734010711000},"source":"Crossref","is-referenced-by-count":1,"title":["Synchronous gangrenous cholecystitis and appendicitis secondary to appendiceal diverticulum perforation"],"prefix":"10.1093","volume":"2024","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5141-0446","authenticated-orcid":false,"given":"Sarah","family":"Fennelly","sequence":"first","affiliation":[{"name":"Northern Health Acute General Surgery Unit , 185 Cooper Street, Epping 3076 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marilla","family":"Dickfos","sequence":"additional","affiliation":[{"name":"Northern Health Acute General Surgery Unit , 185 Cooper Street, Epping 3076 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jyothirmayi","family":"Velaga","sequence":"additional","affiliation":[{"name":"Northern Health Acute General Surgery Unit , 185 Cooper Street, Epping 3076 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nezor","family":"Houli","sequence":"additional","affiliation":[{"name":"Northern Health Acute General Surgery Unit , 185 Cooper Street, Epping 3076 ,","place":["Australia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,12,12]]},"reference":[{"key":"2024121213381845100_ref1","doi-asserted-by":"crossref","DOI":"10.1016\/j.epsc.2022.102451","article-title":"Synchronous gallbladder perforation and appendicitis in a pediatric patient","volume-title":"J Pediatr Surg Case Rep","author":"Aceves-Ayala","year":"2022"},{"key":"2024121213381845100_ref2","doi-asserted-by":"publisher","first-page":"e21973","DOI":"10.7759\/cureus.21973","article-title":"Incidental finding of acute appendicitis during laparoscopic cholecystectomy for an acute calculous cholecystitis","volume":"14","author":"Alkhurmudi","year":"2022","journal-title":"Cureus"},{"key":"2024121213381845100_ref3","doi-asserted-by":"publisher","first-page":"798","DOI":"10.1111\/j.1445-2197.1977.tb06627.x","article-title":"Double pathology in acute cholecystitis","volume":"47","author":"Black","year":"1977","journal-title":"Aust N Z J Surg"},{"key":"2024121213381845100_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-208916","article-title":"Concurrent presentation of appendicitis and acute cholecystitis: diagnosis of rare occurrence","volume":"2015","author":"Gandhi","year":"2015","journal-title":"BMJ Case Rep"},{"key":"2024121213381845100_ref5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/575930","article-title":"Simultaneous acute cholecystitis and acute appendicitis treated by a single laparoscopic operation","volume":"2012","author":"DeMuro","year":"2012","journal-title":"Case Rep Surg"},{"key":"2024121213381845100_ref6","doi-asserted-by":"publisher","first-page":"e40411","DOI":"10.7759\/cureus.40411","article-title":"Synchronous acute appendicitis and acute cholecystitis: a case report","volume":"15","author":"Kancheva","year":"2023","journal-title":"Cureus"},{"key":"2024121213381845100_ref7","article-title":"Successful nonsurgical treatment for synchronous acute cholecystitis and acute appendicitis: a case report and review of the literatures.","volume":"34","author":"Lee","year":"2014","journal-title":"J. Med. Sci."},{"key":"2024121213381845100_ref8","doi-asserted-by":"crossref","first-page":"106296","DOI":"10.1016\/j.ijscr.2021.106296","article-title":"Synchronous presentation of acute cholecystitis and acute appendicitis successful treatment in one step laparoscopic procedure. A case series and literature review","volume":"86","author":"Nahidi","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"2024121213381845100_ref9","doi-asserted-by":"publisher","first-page":"S715","DOI":"10.14309\/01.ajg.0000779880.85320.68","article-title":"Concurrent acute appendicitis and cholecystitis in a patient with right upper quadrant abdominal pain","volume":"116","author":"Nehme","year":"2021","journal-title":"Am J Gastroenterol"},{"key":"2024121213381845100_ref10","doi-asserted-by":"publisher","first-page":"50","DOI":"10.1016\/j.circir.2015.06.008","article-title":"Synchronous acute cholecystolithiasis and perforated acute appendicitis","volume":"84","author":"Padr\u00f3n-Arredondo","year":"2016","journal-title":"Case report Cir Cir"},{"key":"2024121213381845100_ref11","doi-asserted-by":"publisher","first-page":"rjaa447","DOI":"10.1093\/jscr\/rjaa447","article-title":"Acute appendicitis located within Amyand\u2019s hernia - a complex case with concurrent acute cholecystitis","volume":"2020","author":"Sabri","year":"2020","journal-title":"J Surg Case Rep"},{"key":"2024121213381845100_ref12","doi-asserted-by":"publisher","first-page":"551","DOI":"10.1186\/1752-1947-5-551","article-title":"Synchronous presentation of acute acalculous cholecystitis and appendicitis: a case report","volume":"5","author":"Sahebally","year":"2011","journal-title":"J Med Case Reports"},{"key":"2024121213381845100_ref13","first-page":"57","article-title":"Acute cholecystitis with perforated appendicitis: the first reported case","volume":"2","author":"Salih","year":"2016","journal-title":"J Case Rep Images Surg"},{"key":"2024121213381845100_ref14","doi-asserted-by":"publisher","DOI":"10.21037\/ales.2017.02.30","article-title":"Co-existent appendicitis and cholecystitis","volume":"2","author":"Victory","year":"2017","journal-title":"Ann Laparosc Endosc Surg"},{"key":"2024121213381845100_ref15","doi-asserted-by":"crossref","DOI":"10.1016\/j.jtumed.2021.03.003","article-title":"Synchronous acute sub-serosal appendicitis and cholecystitis, in a patient with a long standing small bowel neuroendocrine tumor","volume-title":"J Taibah Univ Med Sci","author":"Al-Nabulsi","year":"2021"},{"key":"2024121213381845100_ref16","doi-asserted-by":"publisher","first-page":"237","DOI":"10.1097\/SLA.0000000000002188","article-title":"The global incidence of appendicitis: a systematic review of population-based studies","volume":"266","author":"Ferris","year":"2017","journal-title":"Ann Surg"},{"key":"2024121213381845100_ref17","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1053\/j.tvir.2015.07.009","article-title":"Clinical presentation, imaging, and management of acute cholecystitis","volume":"18","author":"Katabathina","year":"2015","journal-title":"Tech Vasc Interv Radiol"},{"key":"2024121213381845100_ref18","doi-asserted-by":"publisher","first-page":"204","DOI":"10.1177\/00031348221124334","article-title":"Diabetes as a risk factor for perforated appendicitis: a National Analysis","volume":"89","author":"Panahi","year":"2023","journal-title":"Am Surg"},{"key":"2024121213381845100_ref19","doi-asserted-by":"publisher","first-page":"e7728","DOI":"10.7759\/cureus.7728","article-title":"Perforated gangrenous gallbladder in an asymptomatic patient","volume":"12","author":"Faraji","year":"2020","journal-title":"Cureus"},{"key":"2024121213381845100_ref20","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.12998\/wjcc.v6.i15.1007","article-title":"Gangrenous cholecystitis: a silent but potential fatal disease in patients with diabetic neuropathy. A case report","volume":"6","author":"Mehrzad","year":"2018","journal-title":"World J Clin Cases"},{"key":"2024121213381845100_ref21","doi-asserted-by":"publisher","first-page":"428","DOI":"10.1046\/j.1440-1622.2000.01851.x","article-title":"Gangrenous cholecystitis in the laparoscopic era","volume":"70","author":"Hunt","year":"2000","journal-title":"Aust N Z J Surg"},{"key":"2024121213381845100_ref22","doi-asserted-by":"publisher","first-page":"e44934","DOI":"10.7759\/cureus.44934","article-title":"Accuracy of ultrasound and computed tomography in diagnosing acute cholecystitis patients in a tertiary care center in Saudi Arabia","volume":"15","author":"Khafaji","year":"2023","journal-title":"Cureus"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/12\/rjae785\/61080232\/rjae785.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2024\/12\/rjae785\/61080232\/rjae785.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,12]],"date-time":"2024-12-12T13:38:34Z","timestamp":1734010714000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae785\/7921885"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,1]]},"references-count":22,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae785","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2024,12]]},"published":{"date-parts":[[2024,12,1]]},"article-number":"rjae785"}}