{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T07:28:17Z","timestamp":1792481297731,"version":"4.5.0"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"12","license":[{"start":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T00:00:00Z","timestamp":1734480000000},"content-version":"vor","delay-in-days":17,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Schwannomas commonly occur in the head and neck region but are rarely seen in the gastrointestinal tract; the stomach and small intestine are the most commonly involved sites. These tumors are usually misdiagnosed as gastrointestinal stromal tumors (GISTs) before histopathological confirmation due to radiological similarity. GI schwannomas show positivity for S100 protein and vimentin but are negative for CD 117 and CD 34, which helps in differentiating the tumor from GISTs. Case 1: a 70-year-old woman was referred to our hospital by complaints of abdominal pain and discomfort. Upper GI endoscopy demonstrated a protruding lesion at the lesser curvature of the gastric body, and fine-needle aspiration biopsy showed chronic inflammation without malignancy. Since the lesion was suspected to be GIST, this patient had surgery, and a gastric schwannoma was resected successfully. Case 2: a 66-year-old female with anemia and abdominal discomfort was found to have a submucosal elevated mass at the greater curvature of the antrum. Fine needle aspiration biopsy was suggestive of a spindle cell tumor resembling GIST. The patient underwent subtotal gastrectomy with Roux-en-Y reconstruction. Histopathology confirmed schwannoma. It is necessary to differentiate gastric schwannomas from other submucosal tumors of the stomach, especially GISTs. Surgical complete resection of schwannomas usually has a good prognosis with a low probability of recurrence. Though rare, gastric schwannomas should be included in the differential diagnosis of submucosal gastric tumors because the correct identification of this tumor type helps in proper management and evasion of unnecessary extensive surgery.<\/jats:p>","DOI":"10.1093\/jscr\/rjae793","type":"journal-article","created":{"date-parts":[[2024,12,18]],"date-time":"2024-12-18T23:18:58Z","timestamp":1734563938000},"source":"Crossref","is-referenced-by-count":3,"title":["Differential diagnosis of submucosal gastric tumors: gastric schwannomas misdiagnosed as GISTs"],"prefix":"10.1093","volume":"2024","author":[{"given":"Mutlu","family":"Unver","sequence":"first","affiliation":[{"name":"Department of General Surgery, \u0130zmir University of Economics , Fevzi \u00c7akmak, Sakarya Cd. No. 156, 35330 Bal\u00e7ova\/\u0130zmir ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2710-4403","authenticated-orcid":false,"given":"Suleyman Ca\u011flar","family":"Ertekin","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Alt\u0131nba\u015f University , Bah\u00e7elievler Mah. E5 Karayolu\/K\u00fclt\u00fcr Sok. No. 1, 34180 Alt\u0131nba\u015f \u00dcniversitesi T\u0131p Fak\u00fcltesi, Istanbul ,","place":["T\u00fcrkiye"]},{"name":"Department of General Surgery , \u0130zmir T\u0131naztepe University Galen Hospital Manavkuyu, 250. Sk. No. 23, 35001 Bayrakl\u0131\/\u0130zmir ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ey\u00fcp","family":"Kebapc\u0131","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Bakircay University Cigli Training and Research Hospital , Yeni Mahalle, 8780\/1. Sk. No. 18, 35620 \u00c7i\u011fli\/\u0130zmir ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mustafa","family":"Olmez","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Tepecik Training and Research Hospital , Yeni\u015fehir, Gaziler Cd No. 468, 35020 Konak\/\u0130zmir ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erhan","family":"Ergin","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology, Manisa City Hospital , Adnan Menderes, 132. Sk. No. 15, 45040 \u015eehzadeler\/Manisa ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Safak","family":"Ozturk","sequence":"additional","affiliation":[{"name":"Department of General Surgery, \u0130zmir University of Economics , Fevzi \u00c7akmak, Sakarya Cd. 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No. 156, 35330 Bal\u00e7ova\/\u0130zmir ,","place":["T\u00fcrkiye"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2024,12,18]]},"reference":[{"key":"2024121823185012100_ref1","doi-asserted-by":"publisher","first-page":"502","DOI":"10.1159\/000331561","article-title":"An individual with gastric schwannoma with pathologically malignant potential surviving two years after laparoscopy-assisted partial gastrectomy","volume":"5","author":"Watanabe","year":"2011","journal-title":"Case Rep Gastroenterol"},{"key":"2024121823185012100_ref2","doi-asserted-by":"publisher","first-page":"7397","DOI":"10.3748\/wjg.v18.i48.7397","article-title":"Endoscopic ultrasound features of gastric schwannomas with radiological correlation: a case series report","volume":"18","author":"Zhong","year":"2012","journal-title":"World J Gastroenterol"},{"key":"2024121823185012100_ref3","doi-asserted-by":"publisher","first-page":"257","DOI":"10.1016\/S0046-8177(88)80518-5","article-title":"Benign schwannoma of the gastrointestinal tract: a clinicopathologic and immunohistochemical study","volume":"19","author":"Daimaru","year":"1988","journal-title":"Hum Pathol"},{"key":"2024121823185012100_ref4","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1155\/2012\/742035","article-title":"Endometriosis of the terminal ileum: a diagnostic dilemma","volume":"2012","author":"Ozturk","year":"2013","journal-title":"Case Rep Pathol"},{"key":"2024121823185012100_ref5","doi-asserted-by":"publisher","first-page":"650","DOI":"10.1016\/j.humpath.2011.07.006","article-title":"Gastric schwannoma: a clinicopathologic study of 51 cases and critical review of the literature","volume":"43","author":"Voltaggio","year":"2012","journal-title":"Hum Pathol"},{"key":"2024121823185012100_ref6","doi-asserted-by":"publisher","first-page":"411","DOI":"10.1007\/s00428-010-0886-8","article-title":"Peripheral nerve sheath tumors of the gastrointestinal tract: a multicenter study of 58 patients including NF1-associated gastric schwannoma and unusual morphologic variants","volume":"456","author":"Agaimy","year":"2010","journal-title":"Virchows Arch"},{"key":"2024121823185012100_ref7","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1007\/s004280000338","article-title":"Gastrointestinal stromal tumors--definition, clinical, histological, immunohistochemical, and molecular genetic features and differential diagnosis","volume":"438","author":"Miettinen","year":"2001","journal-title":"Virchows Arch"},{"key":"2024121823185012100_ref8","doi-asserted-by":"publisher","first-page":"280982","DOI":"10.1155\/2012\/280982","article-title":"Gastric schwannoma: a rare but important differential diagnosis of a gastric submucosal mass","volume":"2012","author":"Yoon","year":"2012","journal-title":"Case Rep Surg"},{"key":"2024121823185012100_ref9","doi-asserted-by":"publisher","first-page":"293","DOI":"10.1155\/2012\/742035","article-title":"Gastric schwannoma: clinical and pathologic considerations","volume":"59","author":"Melvin","year":"1993","journal-title":"Am Surg"},{"key":"2024121823185012100_ref10","first-page":"583","article-title":"Gastric schwannoma","volume":"67","author":"Lin","year":"2004","journal-title":"J Chin Med Assoc"},{"key":"2024121823185012100_ref11","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1055\/s-2008-1055869","article-title":"Neurogenic tumors of the stomach. 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