{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:34Z","timestamp":1753877194682,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T00:00:00Z","timestamp":1734825600000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Laparoscopic cholecystectomy is the preferred method for treating acute cholecystitis. Although the incidence of postoperative infections in laparoscopic cholecystectomy is low, serious postoperative surgical site infections are still reported. Hepatic abscesses, particularly fungal, can occur post-cholecystectomy leading to significant mortality and morbidity. We report a case of a 58-year-old female who underwent laparoscopic cholecystectomy and subsequently developed fever, jaundice, and right upper quadrant pain. Laboratory results showed deranged liver function tests with raised inflammatory markers. Radiographic investigations, including CT and MRI, revealed an irregular hilar lesion with periportal changes suggestive of an abscess with portal vein thrombosis. Histopathological examination of the biopsy obtained from the hilar lesion showed a fungal hepatic infection, and particularly conidiobolomycosis. To our best knowledge, this is the first case that reports this fungal infection as a complication of laparoscopic cholecystectomy. The patient was managed with a combination of intravenous antibiotics and antifungals, which yielded mild improvement. Unfortunately, the patient decided to leave the hospital against medical advice, limiting the information on the disease course.<\/jats:p>","DOI":"10.1093\/jscr\/rjae802","type":"journal-article","created":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T16:47:19Z","timestamp":1734886039000},"source":"Crossref","is-referenced-by-count":0,"title":["Fungal hepatic abscess formation postlaparoscopic cholecystectomy"],"prefix":"10.1093","volume":"2025","author":[{"given":"Dana","family":"AlNuaimi","sequence":"first","affiliation":[{"name":"Department of Health , Abu Dhabi ,","place":["United Arab Emirates"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghufran","family":"Saeed","sequence":"additional","affiliation":[{"name":"Sheikh Khalifa Medical City , Abu Dhabi ,","place":["United Arab Emirates"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0117-3299","authenticated-orcid":false,"given":"Shareefa","family":"Abdulghaffar","sequence":"additional","affiliation":[{"name":"Dubai Health , Dubai ,","place":["United Arab Emirates"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem","family":"AlKetbi","sequence":"additional","affiliation":[{"name":"Dubai Health , Dubai ,","place":["United Arab Emirates"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Essa M","family":"Aleassa","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Abu Dhabi , Abu Dhabi ,","place":["United Arab Emirates"]},{"name":"Khalifa University , Abu Dhabi ,","place":["United Arab Emirates"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Numan Cem","family":"Balci","sequence":"additional","affiliation":[{"name":"Cleveland Clinic Abu Dhabi , Abu Dhabi ,","place":["United Arab Emirates"]},{"name":"Cleveland Clinic Lerner College of Medicine , Cleveland, OH ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2024,12,21]]},"reference":[{"key":"2024122216470479000_ref1","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjs038","article-title":"Abdominal wall abscess containing gallstones as a late complication to laparoscopic cholecystectomy performed 17 years earlier","volume":"2013","author":"Christensen","year":"2013","journal-title":"J Surg Case Rep"},{"key":"2024122216470479000_ref2","doi-asserted-by":"publisher","first-page":"196","DOI":"10.1016\/j.ijsu.2015.04.083","article-title":"Open versus laparoscopic cholecystectomy in acute cholecystitis. Systematic review and meta-analysis","volume":"18","author":"Coccolini","year":"2015","journal-title":"Int J Surg"},{"key":"2024122216470479000_ref3","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1016\/s0195-6701(98)90240-7","article-title":"Infections and bacteriological data after laparoscopic and open gallbladder surgery","volume":"39","author":"Den Hoed","year":"1998","journal-title":"J Hosp Infect"},{"key":"2024122216470479000_ref4","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-222013","article-title":"Fungal liver abscess in an immunocompetent patient who underwent repeated ERCPs and subtotal cholecystectomy","volume":"2018","author":"Hasan","year":"2018","journal-title":"BMJ Case Rep"},{"key":"2024122216470479000_ref5","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000099009","article-title":"Postoperative bacterial\/fungal infections: a challenging problem in critically ill patients after abdominal surgery","volume":"24","author":"Lichtenstern","year":"2007","journal-title":"Dig Surg"},{"key":"2024122216470479000_ref6","doi-asserted-by":"publisher","first-page":"S83","DOI":"10.14309\/00000434-201210001-00192","article-title":"Fungal infections in cholangitis: implementation of diagnostic and therapeutic algorithm","volume":"107","author":"Philipp","year":"2012","journal-title":"Am J Gastroenterol"},{"key":"2024122216470479000_ref7","doi-asserted-by":"publisher","first-page":"2813","DOI":"10.1016\/b978-1-4160-4044-6.50223-5","volume-title":"Zygomycosis. Feigin and Cherry\u2019s Textbook of Pediatric Infectious Diseases","author":"Zaoutis","year":"2009"},{"key":"2024122216470479000_ref8","first-page":"447","volume-title":"Entomophthoramycosis, Medical Mycology","author":"Kwon-Chung","year":"1992"},{"key":"2024122216470479000_ref9","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1111\/myc.12248","article-title":"Entomophthoromycosis: a challenging emerging disease","volume":"57","author":"El-Shabrawi","year":"2014","journal-title":"Mycoses"},{"volume-title":"StatPearls: Entomophthoromycosis","year":"2023","author":"Sherchan","key":"2024122216470479000_ref10"},{"key":"2024122216470479000_ref11","first-page":"634","volume-title":"Zygomycosis. Diagnostic Pathology. Nonneoplastic Dermatopathology","author":"Hall","year":"2022"},{"key":"2024122216470479000_ref12","doi-asserted-by":"publisher","first-page":"752","DOI":"10.1128\/JCM.01484-10","article-title":"Disseminated human conidiobolomycosis due to Conidiobolus lamprauges","volume":"49","author":"Kimura","year":"2011","journal-title":"J Clin Microbiol"},{"key":"2024122216470479000_ref13","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-5-126","article-title":"Portal vein thrombosis following laparoscopic cholecystectomy complicated by dengue viral infection: a case report","volume":"126","author":"Dan","year":"2011","journal-title":"J Med Case Reports"},{"key":"2024122216470479000_ref14","doi-asserted-by":"publisher","first-page":"166","DOI":"10.4293\/108680812X13291597716663","article-title":"Thrombosis of portal venous system after laparoscopic cholecystectomy in a patient with prothrombin gene mutation","volume":"16","author":"Gul","year":"2012","journal-title":"JSLS"},{"key":"2024122216470479000_ref15","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.30294","article-title":"A rare case of portal vein thrombosis following a successful laparoscopic cholecystectomy","volume":"14","author":"Sood","year":"2022","journal-title":"Cureus"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/1\/rjae802\/61253008\/rjae802.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/1\/rjae802\/61253008\/rjae802.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,22]],"date-time":"2024-12-22T16:47:21Z","timestamp":1734886041000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjae802\/7930227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,21]]},"references-count":15,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2024,12,21]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjae802","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,1]]},"published":{"date-parts":[[2024,12,21]]},"article-number":"rjae802"}}