{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T22:29:43Z","timestamp":1790288983243,"version":"4.1.0"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"1","license":[{"start":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T00:00:00Z","timestamp":1737849600000},"content-version":"vor","delay-in-days":36,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,21]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Mesonephric-like adenocarcinoma (MLA) is a rare and newly recognized subtype of ovarian and endometrial carcinomas, introduced in the 2020 World Health Organization Classification. This tumor likely originates from M\u00fcllerian-derived tissues and often mimics more common ovarian cancers, leading to frequent misdiagnosis. This case study details a 36-year-old woman who presented with urinary symptoms following a hysterectomy. Imaging revealed a significant left ovarian mass, initially misdiagnosed as carcinosarcoma. Pathological evaluation ultimately confirmed MLA, characterized by diverse architectural patterns and specific immunohistochemical markers. The patient underwent chemotherapy due to the locally advanced disease. This case highlights the diagnostic challenges of MLA and emphasizes the need for awareness among clinicians to prevent misdiagnosis. Given its aggressive nature and tendency to early recurrence, further research is essential for establishing standardized diagnostic criteria and treatment protocols for this rare malignancy.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf025","type":"journal-article","created":{"date-parts":[[2025,1,26]],"date-time":"2025-01-26T18:38:51Z","timestamp":1737916731000},"source":"Crossref","is-referenced-by-count":1,"title":["Mesonephric-like adenocarcinoma of the ovary: a case study"],"prefix":"10.1093","volume":"2025","author":[{"given":"Saad","family":"Assila","sequence":"first","affiliation":[{"name":"Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center , Allal Al Fassi Avenue, Rabat 10100 ,","place":["Morocco"]},{"name":"Department of Pathology, Faculty of Medicine and Pharmacy, Mohammed V University , Mohamed Belarbi Alaoui Avenue, Rabat 10000 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Khannoussi","sequence":"additional","affiliation":[{"name":"Department of Pathology of the National Institute of Oncology, Ibn Sina University Hospital Center , Allal Al Fassi Avenue, Rabat 10100 ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy, Mohammed V University , Mohamed Belarbi Alaoui Avenue, Rabat 10000 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,1,26]]},"reference":[{"key":"2025012618384138200_ref1","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1186\/s13048-024-01383-7","article-title":"Mesonephric-like adenocarcinoma of the ovary","volume":"17","author":"Yang","year":"2024","journal-title":"J Ovarian Res"},{"key":"2025012618384138200_ref2","doi-asserted-by":"publisher","first-page":"208","DOI":"10.1097\/PAP.0000000000000342","article-title":"Mesonephric-like adenocarcinoma of the female genital tract: from morphologic observations to a well-characterized 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wolf in sheep\u2019s clothing","volume":"10","author":"Deolet","year":"2021","journal-title":"J Clin Med"},{"key":"2025012618384138200_ref6","doi-asserted-by":"publisher","first-page":"1013","DOI":"10.1111\/his.12895","article-title":"Hormone receptor-negative, thyroid transcription factor 1-positive uterine and ovarian adenocarcinomas: report of a series of mesonephric-like adenocarcinomas","volume":"68","author":"McFarland","year":"2016","journal-title":"Histopathology"},{"key":"2025012618384138200_ref7","doi-asserted-by":"publisher","first-page":"100657","DOI":"10.1016\/j.gore.2020.100657","article-title":"Mesonephric-like adenocarcinoma of the ovary with co-existent endometriosis: a case report and review of the literature","volume":"34","author":"Seay","year":"2020","journal-title":"Gynecol Oncol Rep"},{"key":"2025012618384138200_ref8","doi-asserted-by":"publisher","first-page":"84","DOI":"10.1097\/PGP.0000000000000573","article-title":"Ovarian combined low-grade serous and mesonephric-like adenocarcinoma: further evidence for a Mullerian origin of mesonephric-like adenocarcinoma","volume":"39","author":"McCluggage","year":"2020","journal-title":"Int J Gynecol Pathol"},{"key":"2025012618384138200_ref9","doi-asserted-by":"publisher","first-page":"326","DOI":"10.3390\/diagnostics12020326","article-title":"Mesonephric-like adenocarcinoma of the ovary: clinicopathological and molecular characteristics","volume":"12","author":"Koh","year":"2022","journal-title":"Diagnostics"},{"key":"2025012618384138200_ref10","doi-asserted-by":"publisher","first-page":"227","DOI":"10.1097\/PAS.0000000000000958","article-title":"Targeted genomic profiling reveals recurrent KRAS mutations in mesonephric-like adenocarcinomas of the female genital tract","volume":"42","author":"Mirkovic","year":"2018","journal-title":"Am J Surg 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