{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:32Z","timestamp":1753877252285,"version":"3.41.2"},"reference-count":11,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Schwannoma is a well encapsulated benign nerve sheath tumor of neuroectodermal origin with an indolent progression unless associated with malignancy. Schwannomas arise from the Schwann cells as do neurofibromas and are usually solitary except in Von Recklinghausen\u2019s disease. The occurrence of a schwannoma in the head and neck region is about 25%; however, submandibular gland schwannoma is a rare form of an extracranial neurogenic tumor arising from peripheral, central, or autonomic nerves. We report a rare case of a submandibular schwannoma in a patient with neurofibromatosis 1 which presented as a painless swelling in the submandibular region, treated by total excision of the submandibular gland. There was no postoperative deficit or recurrence within 3\u00a0months of follow-up. Our findings in this case suggest schwannoma of the salivary gland as a differential diagnosis of swelling in the submandibular area although rare, especially in a patient with neurofibromatosis 1.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf043","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T22:18:41Z","timestamp":1741126721000},"source":"Crossref","is-referenced-by-count":0,"title":["Schwannoma of the submandibular gland in neurofibromatosis 1: a case report"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-7708-1789","authenticated-orcid":false,"given":"Hephzibah Grace","family":"Mandam","sequence":"first","affiliation":[{"name":"Shri Atal Bihari Vajpayee Medical College and Research Institute , Lady Curzon Rd, Shivajinagar, Bangalore 560 001 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Swathi","family":"Santharaj","sequence":"additional","affiliation":[{"name":"Shri Atal Bihari Vajpayee Medical College and Research Institute , Lady Curzon Rd, Shivajinagar, Bangalore 560 001 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noor Ul","family":"Hassan","sequence":"additional","affiliation":[{"name":"Bowring and Lady Curzon Hospital , Bangalore 560 001 ,","place":["India"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"2025030422182695400_ref1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1186\/1752-1947-8-231","article-title":"Schwannoma of the submandibular gland: a case report","volume":"8","author":"Aslan","year":"2014","journal-title":"J Med Case Reports"},{"key":"2025030422182695400_ref2","doi-asserted-by":"publisher","first-page":"e36358","DOI":"10.1097\/MD.0000000000036358","article-title":"A case report of giant malignant schwannoma of the sciatic nerve associated with neurofibromatosis-1: a CARE-compliant article","volume":"102","author":"Gokkus","year":"2023","journal-title":"Medicine (Baltimore)"},{"key":"2025030422182695400_ref3","doi-asserted-by":"publisher","first-page":"220","DOI":"10.1590\/S1516-31802007000400005","article-title":"Schwannomas in the head and neck: retrospective analysis of 21 patients and review of the literature","volume":"125","author":"Langner","year":"2007","journal-title":"Sao Paulo Med J"},{"key":"2025030422182695400_ref4","doi-asserted-by":"publisher","first-page":"233","DOI":"10.47102\/annals-acadmedsg.V36N4p233","article-title":"Extracranial non-vestibular head and neck schwannomas: a ten-year experience","volume":"36","author":"Kang","year":"2007","journal-title":"Ann Acad Med Singap"},{"key":"2025030422182695400_ref5","doi-asserted-by":"publisher","first-page":"235","DOI":"10.1186\/1752-1947-8-231","article-title":"Neurilemmoma: review of the literature and report of five cases","volume":"35","author":"Gallo","year":"1997","journal-title":"J Oral Surg"},{"key":"2025030422182695400_ref6","doi-asserted-by":"publisher","DOI":"10.5580\/21f5","article-title":"Schwannoma of the hard plate: a rare case","volume":"4","author":"Dhupar","year":"2011","journal-title":"Internet J Head Neck Surg"},{"key":"2025030422182695400_ref7","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1259\/dmfr\/93898716","article-title":"Schwannoma in the sublingual space","volume":"33","author":"Kawakami","year":"2004","journal-title":"Dentomaxillofac Radiol"},{"key":"2025030422182695400_ref8","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1111\/j.1834-7819.1998.tb00179.x","article-title":"Sublingual hypoglossal neurilemmoma. Case report","volume":"43","author":"Drevelengas","year":"1998","journal-title":"Austral Dental J"},{"key":"2025030422182695400_ref9","doi-asserted-by":"publisher","DOI":"10.53347\/rID-93006","article-title":"Submandibular schwannoma. Case study","author":"Islam","journal-title":"Radiopaediaorg"},{"key":"2025030422182695400_ref10","doi-asserted-by":"publisher","first-page":"1477","DOI":"10.1148\/rg.245045001","article-title":"Schwannoma: radiologic-pathologic correlation","volume":"24","author":"Beaman","year":"2004","journal-title":"Radiographics"},{"key":"2025030422182695400_ref11","doi-asserted-by":"publisher","first-page":"12","DOI":"10.2174\/1874210601812010012","article-title":"A case of schwannoma of the submandibular region","volume":"12","author":"Bamgbose","year":"2018","journal-title":"Open Dent J"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf043\/62206748\/rjaf043.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf043\/62206748\/rjaf043.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T22:18:43Z","timestamp":1741126723000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf043\/8046266"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":11,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf043","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2025,2]]},"article-number":"rjaf043"}}