{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:42Z","timestamp":1753877202752,"version":"3.41.2"},"reference-count":12,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T00:00:00Z","timestamp":1740096000000},"content-version":"vor","delay-in-days":20,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Follicular lymphoma of the gastrointestinal tract is a rare entity accounting for &amp;lt;7% of all non-Hodgkin lymphomas and is more common in the small intestine, whereas colorectal manifestations account for only 1%\u20132% of the cases. Most patients have limited disease with promising overall survival in comparison to nodal lymphoma although the morphologic, immunophenotypic, and genetic aspects of nodal follicular lymphomas remain the same. Despite the lack of randomized clinical trials, chemotherapy is frequently used to treat NCCN grade III and IV colonic follicular lymphomas with favorable prognosis. We hereby present a case of follicular lymphoma of the colon that was treated conservatively with a successful outcome.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf058","type":"journal-article","created":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T15:53:27Z","timestamp":1740153207000},"source":"Crossref","is-referenced-by-count":0,"title":["A large colonic polyp: an atypical presentation of follicular lymphoma"],"prefix":"10.1093","volume":"2025","author":[{"given":"Abraam","family":"Rezkalla","sequence":"first","affiliation":[{"name":"Internal Medicine Department, Saint Joseph\u2019s University Medical Center , 703 Main Street, Paterson, NJ 07503 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Islam","family":"Rajab","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Saint Joseph\u2019s University Medical Center , 703 Main Street, Paterson, NJ 07503 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nagihan","family":"Orhun","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Saint Joseph\u2019s University Medical Center , 703 Main Street, Paterson, NJ 07503 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alaa","family":"Musallam","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Saint Joseph\u2019s University Medical Center , 703 Main Street, Paterson, NJ 07503 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katrina","family":"Villegas","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Saint Joseph\u2019s University Medical Center , 703 Main Street, Paterson, NJ 07503 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-6397-8033","authenticated-orcid":false,"given":"Ahmad","family":"Nouri","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University , Nablus 44839 ,","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,21]]},"reference":[{"key":"2025022115530334100_ref1","doi-asserted-by":"publisher","first-page":"1532","DOI":"10.1111\/j.1349-7006.2011.01980.x","article-title":"Primary gastrointestinal follicular lymphoma involving the duodenal second portion is a distinct entity: a multicenter, retrospective analysis in Japan","volume":"102","author":"Takata","year":"2011","journal-title":"Cancer Sci"},{"key":"2025022115530334100_ref2","doi-asserted-by":"publisher","first-page":"727","DOI":"10.1023\/A:1008282818705","article-title":"Primary extranodal non-Hodgkin\u2019s lymphomas. Part 1: gastrointestinal, cutaneous and genitourinary lymphomas","volume":"8","author":"Zucca","year":"1997","journal-title":"Ann Oncol"},{"key":"2025022115530334100_ref3","doi-asserted-by":"publisher","first-page":"623","DOI":"10.1093\/annonc\/mdg168","article-title":"Primary follicular lymphoma of the gastrointestinal tract: a study of 25 cases and a literature review","volume":"14","author":"Damaj","year":"2003","journal-title":"Ann Oncol"},{"key":"2025022115530334100_ref4","doi-asserted-by":"publisher","first-page":"2","DOI":"10.1016\/j.beha.2017.10.006","article-title":"Pathogenesis of follicular lymphoma","volume":"31","author":"Lackraj","year":"2018","journal-title":"Best Pract Res Clin Haematol"},{"key":"2025022115530334100_ref5","doi-asserted-by":"publisher","first-page":"1255","DOI":"10.1097\/PAS.0b013e318224e661","article-title":"Primary follicular lymphoma of the gastrointestinal tract","volume":"35","author":"Misdraji","year":"2011","journal-title":"Am J Surg Pathol"},{"key":"2025022115530334100_ref6","doi-asserted-by":"publisher","first-page":"377","DOI":"10.1136\/jcp.2007.049825","article-title":"Duodenal follicular lymphomas share common characteristics with mucosa-associated lymphoid tissue lymphomas","volume":"61","author":"Sato","year":"2008","journal-title":"J Clin Pathol"},{"key":"2025022115530334100_ref7","doi-asserted-by":"publisher","first-page":"216","DOI":"10.1097\/00000478-200202000-00008","article-title":"Primary follicular lymphoma of the gastrointestinal tract: a clinical and pathologic study of 26 cases","volume":"26","author":"Shia","year":"2002","journal-title":"Am J Surg Pathol"},{"key":"2025022115530334100_ref8","doi-asserted-by":"publisher","first-page":"940","DOI":"10.1038\/modpathol.2009.51","article-title":"Duodenal and nodal follicular lymphomas are distinct: the former lacks activation-induced cytidine deaminase and follicular dendritic cells despite ongoing somatic hypermutations","volume":"22","author":"Takata","year":"2009","journal-title":"Mod Pathol"},{"key":"2025022115530334100_ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ccr3.4486","article-title":"Primary follicular lymphoma of colon: a case series and review of literature","volume":"9","author":"Mohammed","year":"2021","journal-title":"Clin Case Rep"},{"key":"2025022115530334100_ref10","doi-asserted-by":"publisher","first-page":"3368","DOI":"10.1200\/JCO.2011.40.6546","article-title":"Effectiveness of first-line management strategies for stage I follicular lymphoma: analysis of the national LymphoCare study","volume":"30","author":"Friedberg","year":"2012","journal-title":"J Clin Oncol"},{"key":"2025022115530334100_ref11","doi-asserted-by":"publisher","first-page":"2055","DOI":"10.1182\/blood-2015-11-624288","article-title":"Follicular lymphoma: evolving therapeutic strategies","volume":"127","author":"Kahl","year":"2016","journal-title":"Blood"},{"key":"2025022115530334100_ref12","doi-asserted-by":"publisher","first-page":"2439","DOI":"10.1093\/annonc\/mdt188","article-title":"Bowel perforation in intestinal lymphoma: incidence and clinical features","volume":"24","author":"Vaidya","year":"2013","journal-title":"Ann Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf058\/62047657\/rjaf058.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf058\/62047657\/rjaf058.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T15:53:29Z","timestamp":1740153209000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf058\/8029734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":12,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf058","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2025,2]]},"article-number":"rjaf058"}}