{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:06:43Z","timestamp":1753877203539,"version":"3.41.2"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T00:00:00Z","timestamp":1739923200000},"content-version":"vor","delay-in-days":18,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Granular cell tumor is common over skin and subcutaneous and oral cavity. However, lesion is rare in biliary tract and ever more uncommon in gall bladder. These lesions are often misdiagnosed until proven by histology and immunohistochemistry where tumor is positive for CD 68, S 100 which points them toward neural origin of tumor. We report a case of 69-year-old male referred with a suspected gall bladder mass in Computed tomographic scan of abdomen. Laparotomy was done through Kocher\u2019s incision and extended cholecystectomy was performed. Histopathology and immunohistochemical study helped in determining gall bladder lesion to be granular cell tumor. Therefore, granular cell tumor can be considered a possible differential diagnosis of all the gall bladder lesion suspected of cholecystitis and carcinoma. Margin negative excision of the tumor is a curative approach for the patient.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf071","type":"journal-article","created":{"date-parts":[[2025,2,2]],"date-time":"2025-02-02T12:14:25Z","timestamp":1738498465000},"source":"Crossref","is-referenced-by-count":0,"title":["A rare case of granular cell tumor of gall bladder"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1428-5150","authenticated-orcid":false,"given":"Sunil","family":"Dhakal","sequence":"first","affiliation":[{"name":"Gastrointestinal Surgical Unit, B.P. Koirala Memorial Cancer Hospital , Bharatpur 7, Chitwan 44200 , Bagmati Province,","place":["Nepal"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sapana","family":"Bhandari","sequence":"additional","affiliation":[{"name":"Gastrointestinal Surgical Unit, B.P. Koirala Memorial Cancer Hospital , Bharatpur 7, Chitwan 44200 , Bagmati Province,","place":["Nepal"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Avinam H","family":"Kandangwa","sequence":"additional","affiliation":[{"name":"Gastrointestinal Surgical Unit, B.P. Koirala Memorial Cancer Hospital , Bharatpur 7, Chitwan 44200 , Bagmati Province,","place":["Nepal"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,19]]},"reference":[{"key":"2025021908222825000_ref1","doi-asserted-by":"publisher","first-page":"S756","DOI":"10.14309\/01.ajg.0000708040.58402.86","article-title":"S1498\u2003granular cell tumor of the gallbladder following symptoms of cholecystitis: a case report","volume":"115","author":"Nguyen","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"2025021908222825000_ref2","first-page":"331","article-title":"Granular cell tumor of the biliary tract","volume":"6","author":"Patel","year":"2010","journal-title":"Gastroenterol Hepatol (N Y)"},{"key":"2025021908222825000_ref3","doi-asserted-by":"publisher","first-page":"89","DOI":"10.4132\/jptm.2014.10.07","article-title":"Biliary granular cell tumor","volume":"49","author":"Jung","year":"2015","journal-title":"J Pathol Transl Med"},{"key":"2025021908222825000_ref4","doi-asserted-by":"publisher","first-page":"771","DOI":"10.5858\/2004-128-771-GCTIAO","article-title":"Granular cell tumor: immunohistochemical assessment of inhibin-alpha, protein gene product 9.5, S100 protein, CD68, and Ki-67 proliferative index with clinical correlation","volume":"128","author":"Le","year":"2004","journal-title":"Arch Pathol Lab Med"},{"key":"2025021908222825000_ref5","doi-asserted-by":"publisher","first-page":"rjz145","DOI":"10.1093\/jscr\/rjz145","article-title":"Granular cell tumor of the gallbladder: case report and review of the literature","volume":"2019","author":"Abdelrahim","year":"2019","journal-title":"J Surg Case Rep"},{"key":"2025021908222825000_ref6","doi-asserted-by":"publisher","first-page":"439","DOI":"10.20524\/aog.2018.0275","article-title":"Gastrointestinal and biliary granular cell tumor: diagnosis and management","volume":"31","author":"Barakat","year":"2018","journal-title":"Ann Gastroenterol"},{"key":"2025021908222825000_ref7","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1159\/000018858","article-title":"Granular cell tumor at the hepatic duct confluence mimicking Klatskin tumor. A report of two cases and a review of the literature","volume":"17","author":"Boekhorst","year":"2000","journal-title":"Dig Surg"},{"key":"2025021908222825000_ref8","doi-asserted-by":"publisher","first-page":"6324","DOI":"10.3748\/wjg.v18.i43.6324","article-title":"Granular cell tumor of the common bile duct: a Japanese case","volume":"18","author":"Saito","year":"2012","journal-title":"World J Gastroenterol"},{"key":"2025021908222825000_ref9","doi-asserted-by":"publisher","first-page":"967","DOI":"10.5858\/1999-123-0967-MGCTOT","article-title":"Multifocal granular cell tumor of the esophagus and proximal stomach with infiltrative pattern: a case report and review of the literature","volume":"123","author":"David","year":"1999","journal-title":"Arch Pathol Lab Med"},{"key":"2025021908222825000_ref10","volume-title":"MacSween\u2019s Pathology of the Liver","author":"Burt","year":"2007","edition":"5th"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf071\/61948806\/rjaf071.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf071\/61948806\/rjaf071.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,19]],"date-time":"2025-02-19T08:22:48Z","timestamp":1739953368000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf071\/8021311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":10,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf071","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2025,2]]},"article-number":"rjaf071"}}