{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T17:27:45Z","timestamp":1769880465332,"version":"3.49.0"},"reference-count":20,"publisher":"Oxford University Press (OUP)","issue":"2","license":[{"start":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T00:00:00Z","timestamp":1740700800000},"content-version":"vor","delay-in-days":27,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Meckel's diverticulum (MD) is a common congenital anomaly of the gastrointestinal tract, often asymptomatic but occasionally presenting with various complications. Neuroendocrine tumors (NETs) are slow-growing neoplasms that mostly originate from the small intestine. The typical age for the presence of a carcinoid tumor within MD is above 50s. NETs reported to be the most common primary malignancy originating from MD in elderly. We report the first case of a female child who demonstrated five episodes of intussusception, ending in surgical resection revealing a NET within MD. The histopathology study proved a low-grade tumor with no evidence of necrosis. Current literature lacks definitive guidelines for managing NET in MD cases, especially in pediatric populations, necessitating further research for optimal treatment strategies. Prompt removal of the diverticulum upon discovery is advised to enable early detection and treatment of carcinoid tumors, thereby avoiding potential complications or advanced disease stages.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf085","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T22:17:51Z","timestamp":1741126671000},"source":"Crossref","is-referenced-by-count":1,"title":["Recurrent intussusception in a child revealing a neuroendocrine tumor within a Meckel's diverticulum: a case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Hussein","family":"Naji","sequence":"first","affiliation":[{"name":"Pediatric Surgery Department, Mediclinic Parkview Hospital , Albarsha, Dubai ,","place":["UAE"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reem","family":"Allateef","sequence":"additional","affiliation":[{"name":"Family Medicine Department, Mediclinic Parkview Hospital , Albarsha, Dubai ,","place":["UAE"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aftab","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, Mediclinic Parkview Hospital , Albarsha, Dubai ,","place":["UAE"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shahzad","family":"Yousaf","sequence":"additional","affiliation":[{"name":"General Surgery Department, Mediclinic Parkview Hospital , Albarsha, Dubai ,","place":["UAE"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ghassan","family":"Nakib","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, Mediclinic Parkview Hospital , Albarsha, Dubai ,","place":["UAE"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3727-1547","authenticated-orcid":false,"given":"Rawan","family":"Alhalabi","sequence":"additional","affiliation":[{"name":"Pediatric Department, American Hospital Dubai, Oud Metha , Dubai ,","place":["UAE"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,2,28]]},"reference":[{"key":"2025030422173757100_ref1","doi-asserted-by":"publisher","first-page":"529","DOI":"10.1097\/01.sla.0000154270.14308.5f","article-title":"Meckel diverticulum: the Mayo Clinic experience with 1476 patients (1950-2002)","volume":"241","author":"Park","year":"2005","journal-title":"Ann Surg"},{"key":"2025030422173757100_ref2","volume-title":"StatPearls [Internet]","author":"An"},{"key":"2025030422173757100_ref3","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1186\/1477-7819-12-144","article-title":"Incidental finding of carcinoid tumor on Meckel's diverticulum: case report and literature review, should prophylactic resection be recommended?","volume":"12","author":"Caracappa","year":"2014","journal-title":"World J Surg Oncol"},{"key":"2025030422173757100_ref4","doi-asserted-by":"publisher","first-page":"e69235","DOI":"10.7759\/cureus.69235","article-title":"A case report of axial torsion of Meckel's diverticulum: an acute abdomen without mechanical bowel obstruction in a child","volume":"16","author":"Chaaban","year":"2024","journal-title":"Cureus"},{"key":"2025030422173757100_ref5","doi-asserted-by":"publisher","first-page":"e27625","DOI":"10.7759\/cureus.27625","article-title":"Incidental Meckel's diverticulum with neuroendocrine tumor","volume":"14","author":"Chan","year":"2022","journal-title":"Cureus"},{"key":"2025030422173757100_ref6","doi-asserted-by":"publisher","first-page":"1125","DOI":"10.1177\/000313481908501010","article-title":"Neuroendocrine Tumors of Meckel's diverticula: rare but fare well","volume":"85","author":"De Andrade","year":"2019","journal-title":"Am Surg"},{"key":"2025030422173757100_ref7","volume-title":"StatPearls [Internet]","author":"Cingam","year":"2024"},{"key":"2025030422173757100_ref8","doi-asserted-by":"publisher","first-page":"92","DOI":"10.1007\/s00268-004-7443-z","article-title":"An analysis of rare carcinoid tumors: clarifying these clinical conundrums","volume":"29","author":"Modlin","year":"2005","journal-title":"World J Surg"},{"key":"2025030422173757100_ref9","doi-asserted-by":"publisher","first-page":"1436","DOI":"10.1002\/1097-0142(196906)23:6&lt;1436::aid-cncr2820230627&gt;3.0.co;2-6","article-title":"Carcinoid of Meckel's diverticulum. Report of a case and review of the literature","volume":"23","author":"Weitzner","year":"1969","journal-title":"Cancer"},{"key":"2025030422173757100_ref10","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/S0140-6736(01)12311-1","article-title":"A case ofcarcinoid tumour of a Meckel\u2019s diverticulum","volume":"2","author":"Hicks","year":"1922","journal-title":"Lancet"},{"key":"2025030422173757100_ref11","article-title":"Well differentiated neuroendocrine tumor","author":"Martinez","journal-title":"PathologyOutlines.com"},{"key":"2025030422173757100_ref12","doi-asserted-by":"publisher","first-page":"2","DOI":"10.3389\/fonc.2013.00002","article-title":"Histopathology of gastrointestinal neuroendocrine neoplasms.","volume":"3","author":"Hirabayashi","year":"2013","journal-title":"Front. Oncologia"},{"key":"2025030422173757100_ref13","volume-title":"WHO Classification of Tumours of the Digestive System","author":"Bosman","year":"2010","edition":"4th"},{"key":"2025030422173757100_ref14","doi-asserted-by":"publisher","first-page":"813","DOI":"10.1002\/(sici)1097-0142(19970215)79:4&lt;813::aid-cncr19&gt;3.0.co;2-2","article-title":"An analysis of 8305 cases of carcinoid tumors","volume":"79","author":"Modlin","year":"1997","journal-title":"Cancer"},{"key":"2025030422173757100_ref15","first-page":"501","article-title":"Il carcinoide del diverticolo di Meckel [carcinoid of Meckel's diverticulum]","volume":"50","author":"Leinati","year":"1995","journal-title":"Minerva Chir"},{"key":"2025030422173757100_ref16","doi-asserted-by":"publisher","first-page":"815","DOI":"10.1097\/00000658-199906000-00008","article-title":"Prognosis and survival in patients with gastrointestinal tract carcinoid tumors","volume":"229","author":"Shebani","year":"1999","journal-title":"Ann Surg"},{"key":"2025030422173757100_ref17","doi-asserted-by":"publisher","first-page":"732","DOI":"10.1111\/j.1445-2197.1993.tb00503.x","article-title":"Carcinoid syndrome secondary to a primary tumour in a Meckel's diverticulum","volume":"63","author":"Pyke","year":"1993","journal-title":"Aust N Z J Surg"},{"key":"2025030422173757100_ref18","first-page":"353","article-title":"Carcinoids of the small intestine: a statistical evaluation of 1102 cases collected from the literature","volume":"16","author":"Soga","year":"1997","journal-title":"J Exp Clin Cancer Res"},{"key":"2025030422173757100_ref19","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1097\/SLA.0b013e3181ef488d","article-title":"Meckel's diverticulum--a high-risk region for malignancy in the ileum. Insights from a population-based epidemiological study and implications in surgical management","volume":"253","author":"Thirunavukarasu","year":"2011","journal-title":"Ann Surg"},{"key":"2025030422173757100_ref20","first-page":"669","article-title":"The carcinoid tumour in Meckel's diverticulum: how to treat young adults with appendicitis?--case report","volume":"36","author":"Stifter","year":"2012","journal-title":"Coll Antropol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf085\/62206716\/rjaf085.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/2\/rjaf085\/62206716\/rjaf085.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T22:17:54Z","timestamp":1741126674000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf085\/8046262"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2]]},"references-count":20,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2025,2,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf085","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,2]]},"published":{"date-parts":[[2025,2]]},"article-number":"rjaf085"}}