{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T16:49:10Z","timestamp":1775148550999,"version":"3.50.1"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"4","license":[{"start":{"date-parts":[[2026,4,2]],"date-time":"2026-04-02T00:00:00Z","timestamp":1775088000000},"content-version":"vor","delay-in-days":1,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,4,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Fluoroquinolones (FQs) are widely used antibiotics with a broad antibacterial spectrum. However, recent studies have raised concerns regarding the potential association of FQs with an increased risk of aortic aneurysm and aortic dissection. We report a case of an older patient with stable blood pressure and no aortic dilation who developed a thoracic aortic rupture following repeated FQ administration. Although a direct causal relationship between FQ exposure and aortic rupture remains unproven in this single case, this case suggests the need for careful monitoring for possible aortic events, particularly in older patients requiring repeated FQ therapy.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf1115","type":"journal-article","created":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T12:13:24Z","timestamp":1769516004000},"source":"Crossref","is-referenced-by-count":0,"title":["Thoracic aortic rupture in a patient with repeated oral fluoroquinolone administration"],"prefix":"10.1093","volume":"2026","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8150-2552","authenticated-orcid":false,"given":"Masahiko","family":"Narita","sequence":"first","affiliation":[{"name":"Department of Cardiovascular Surgery, Steel Memorial Muroran Hospital , Chiribetsucho 1-45, Muroran 050-0076 ,","place":["Japan"]},{"name":"Department of Cardiac Surgery, Asahikawa Medical University , Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nobuyuki","family":"Akasaka","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Steel Memorial Muroran Hospital , Chiribetsucho 1-45, Muroran 050-0076 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kentaro","family":"Shirakura","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Asahikawa Medical University , Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hana","family":"Fukuta","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Steel Memorial Muroran Hospital , Chiribetsucho 1-45, Muroran 050-0076 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tomoki","family":"Nakatsu","sequence":"additional","affiliation":[{"name":"Department of Cardiovascular Surgery, Steel Memorial Muroran Hospital , Chiribetsucho 1-45, Muroran 050-0076 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroyuki","family":"Kamiya","sequence":"additional","affiliation":[{"name":"Department of Cardiac Surgery, Asahikawa Medical University , Midorigaoka Higashi 2-1-1-1, Asahikawa 078-8510 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2026,4,2]]},"reference":[{"key":"2026040211493122900_ref1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1186\/s12872-021-02258-1","article-title":"Current progress of fluoroquinolones-increased risk of aortic aneurysm and dissection","volume":"21","author":"Jun","year":"2021","journal-title":"BMC Cardiovasc 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