{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T01:11:56Z","timestamp":1778634716728,"version":"3.51.4"},"reference-count":16,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T00:00:00Z","timestamp":1748822400000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Advanced squamous cell carcinoma (SCC) is a challenge for treatment. It is also a risk factor for unintended infestation with Diptera larvae (maggots) known as myiasis. We describe a rare case of cutaneous myiasis located on a giant SCC of the face in an elderly female. Myiasis coupled with malignant skin conditions provides a unique surgical challenge as it is associated with a significantly increased risk of complications and mortalities. A literature review using PUBMED revealed 15 cases of SCC-associated myiasis due to different species. It is not only a disease of older age, as two of the patients were in their 20s. Pain, bleeding, and infection are possible symptoms due to infestation but not all patients reported complaints. Treatment aims to completely remove all maggots and to prevent secondary tissue damage with blindness due to eyeball destruction as one of the worst.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf263","type":"journal-article","created":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T18:05:26Z","timestamp":1748887526000},"source":"Crossref","is-referenced-by-count":1,"title":["Advanced squamous cell carcinoma with myiasis: a case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Ali Adwal","family":"Ali","sequence":"first","affiliation":[{"name":"University of Kirkuk, College of Medicine , Kirkuk ,","place":["Iraq"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anmar Mohammed","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Azadi Teaching Hospital , Kirkuk ,","place":["Iraq"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sajjad Ghanim","family":"Al-Badri","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, University of Baghdad , Baghdad ,","place":["Iraq"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muntadher Yousif Hasan","family":"Al Gehadi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, University of Baghdad , Baghdad ,","place":["Iraq"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nabeel","family":"Al-Fatlawi","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, College of Medicine, University of Baghdad , Baghdad ,","place":["Iraq"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,2]]},"reference":[{"key":"2025060214052140500_ref1","doi-asserted-by":"publisher","first-page":"33","DOI":"10.1016\/j.yadr.2008.09.007","article-title":"Cutaneous squamous cell carcinoma","volume":"24","author":"Garcia-Zuazaga","year":"2008","journal-title":"Adv Dermatol"},{"key":"2025060214052140500_ref2","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1128\/CMR.00010-11","article-title":"Myiasis","volume":"25","author":"Francesconi","year":"2012","journal-title":"Clin Microbiol Rev"},{"key":"2025060214052140500_ref3","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1111\/ijd.12553","article-title":"Squamous cell carcinoma of the skin: epidemiology, classification, management, and novel trends","volume":"54","author":"Kallini","year":"2015","journal-title":"Int J Dermatol"},{"key":"2025060214052140500_ref4","doi-asserted-by":"publisher","first-page":"bcr2012007178","DOI":"10.1136\/bcr-2012-007178","article-title":"Oral squamous cell carcinoma associated with myiasis","volume":"2012","author":"Dharshiyani","year":"2012","journal-title":"BMJ Case Rep"},{"key":"2025060214052140500_ref5","doi-asserted-by":"publisher","first-page":"bcr0420114124","DOI":"10.1136\/bcr.04.2011.4124","article-title":"Myiasis infestation in advanced oral squamous cell carcinoma","volume":"2011","author":"Pessoa","year":"2011","journal-title":"BMJ Case Rep"},{"key":"2025060214052140500_ref6","doi-asserted-by":"publisher","first-page":"e37","DOI":"10.1016\/j.jemermed.2014.04.024","article-title":"Head and neck myiasis, cutaneous malignancy, and infection: a case series and review of the literature","volume":"47","author":"Villwock","year":"2014","journal-title":"J Emerg Med"},{"key":"2025060214052140500_ref7","doi-asserted-by":"publisher","first-page":"24","DOI":"10.3315\/jdcr.2009.1028","article-title":"Painful, slow developing abscesses. Furuncular miyasis due to double skin infestation by Dermatobia hominis","volume":"3","author":"Kr\u00f6nert","year":"2009","journal-title":"J Dermatol Case Rep"},{"key":"2025060214052140500_ref8","doi-asserted-by":"publisher","first-page":"79","DOI":"10.1007\/s10354-014-0326-5","article-title":"Myiasis on squamous cell carcinoma of skin","volume":"165","author":"Wollina","year":"2015","journal-title":"Wien Med Wochenschr"},{"key":"2025060214052140500_ref9","doi-asserted-by":"publisher","first-page":"191","DOI":"10.1016\/S0738-081X(99)00011-5","article-title":"Myiasis","volume":"17","author":"Millikan","year":"1999","journal-title":"Clin Dermatol"},{"key":"2025060214052140500_ref10","doi-asserted-by":"publisher","first-page":"1565","DOI":"10.1136\/bjo.2007.114645","article-title":"Fulminant orbital myiasis in the developed world","volume":"91","author":"Jain","year":"2007","journal-title":"Br J Ophthalmol"},{"key":"2025060214052140500_ref11","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.jaad.2008.09.065","article-title":"Massive oculofacial myiasis infestation with Lucilia sericata","volume":"61","year":"2009","journal-title":"J Am Acad Dermatol"},{"key":"2025060214052140500_ref12","doi-asserted-by":"publisher","first-page":"257","DOI":"10.4103\/0255-0857.66490","article-title":"Ophthalmomyiasis: three cases from North India","volume":"28","author":"Khurana","year":"2010","journal-title":"Indian J Med Microbiol"},{"key":"2025060214052140500_ref13","doi-asserted-by":"publisher","first-page":"285","DOI":"10.1046\/j.1468-3083.2000.00105.x","article-title":"Biosurgery in wound healing\u2014the renaissance of maggot therapy","volume":"14","author":"Wollina","year":"2000","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"2025060214052140500_ref14","doi-asserted-by":"publisher","first-page":"592419","DOI":"10.1155\/2014\/592419","article-title":"Mechanisms of maggot-induced wound healing: what do we know, and where do we go from here?","volume":"2014","author":"Sherman","year":"2014","journal-title":"Evid Based Complement Alternat Med"},{"key":"2025060214052140500_ref15","doi-asserted-by":"publisher","first-page":"341","DOI":"10.1007\/s13744-012-0038-8","article-title":"A severe case of cutaneous myiasis in S\u00e3o Gon\u00e7alo, Brazil, and a simple technique to extract new world screwworm Cochliomyia hominivorax (Coquerel) (Diptera: Calliphoridae)","volume":"41","author":"Batista-da-Silva","year":"2012","journal-title":"Neotrop Entomol"},{"key":"2025060214052140500_ref16","doi-asserted-by":"publisher","first-page":"521","DOI":"10.1590\/S1677-55382007000400010","article-title":"Urgent penectomy in a patient presenting with epidermoid carcinoma of the penis associated to myiasis","volume":"33","author":"Tavares","year":"2007","journal-title":"Int Braz J Urol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/6\/rjaf263\/63419085\/rjaf263.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/6\/rjaf263\/63419085\/rjaf263.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T18:05:27Z","timestamp":1748887527000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf263\/8155327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,31]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf263","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2025,5,31]]},"article-number":"rjaf263"}}