{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T06:30:28Z","timestamp":1787639428549,"version":"build-2736575974"},"reference-count":14,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T00:00:00Z","timestamp":1748649600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Gastrointestinal stromal tumors (GIST) are rare, but they are the most common mesenchymal tumors of the gastrointestinal tract. Here, we present a case of 48\u00a0years medically free female presenting with progressive abdominal distension associated with abdominal discomfort for 2\u00a0months. On physical examination, she was hemodynamically stable with a hugely distended abdomen but soft and lax. Laboratory findings revealed leukocytosis and 16 other labs were unremarkable. Computed tomography (CT) of the abdomen showed a large cystic mass likely arising from small bowel loops measuring 30 \u00d7 19 \u00d7 22\u00a0cm. The lesion has a peripheral soft tissue component measuring 3\u00a0cm in thickness enhanced with contrast material, suggesting hypervascularity. A large air-fluid level with a large volume of intra-cystic fluids was present, which is concerning for associated enteric fistula. No bowel obstruction was observed. The plan was to start the patient on antibiotics and to proceed with diagnostic laparoscopy for cyst excision with possible resection and anastomosis of the small bowel. Furthermore, she was discharged on day 5 with an uneventful postoperative course as the patient was started on IV antibiotics postoperatively and was discharged on oral antibiotics to complete 14\u00a0days. 6-month follow-up patient started on imatinib. Although GISTs presenting as predominantly cystic lesions are very rare, they should be considered one of the differential diagnoses of such a presentation.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf344","type":"journal-article","created":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T15:17:10Z","timestamp":1748704630000},"source":"Crossref","is-referenced-by-count":1,"title":["Gastrointestinal stromal tumor of the small intestine presenting as a giant intratumoral abscess: a rare case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Saleh Husam","family":"Aldeligan","sequence":"first","affiliation":[{"name":"College of Medicine, King Saud University , PO Box 2925, Riyadh 11461 ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Aljunaydil","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University Medical City , PO Box 7805 #37, Riyadh 11472 ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuha","family":"Qattan","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University Medical City , PO Box 7805 #37, Riyadh 11472 ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashwaq A","family":"Almajed","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University Medical City , PO Box 7805 #37, Riyadh 11472 ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Hifni","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University Medical City , PO Box 7805 #37, Riyadh 11472 ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahad","family":"Bamehriz","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University Medical City , PO Box 7805 #37, Riyadh 11472 ,","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,5,31]]},"reference":[{"key":"2025053111170240000_ref1","doi-asserted-by":"publisher","first-page":"1731","DOI":"10.1016\/s0140-6736(07)60780-6","article-title":"Gastrointestinal stromal tumor","volume":"369","author":"Rubin","year":"2007","journal-title":"Lancet"},{"key":"2025053111170240000_ref2","doi-asserted-by":"publisher","first-page":"39","DOI":"10.1016\/j.canep.2015.10.031","article-title":"Global epidemiology of gastrointestinal stromal tumors (GIST): a systematic review of population-based cohort studies","volume":"40","author":"S\u00f8reide","year":"2016","journal-title":"Cancer Epidemiol"},{"key":"2025053111170240000_ref3","doi-asserted-by":"publisher","first-page":"1466","DOI":"10.5858\/2006-130-1466-gstrom","article-title":"Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential 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Gastroenterol"},{"key":"2025053111170240000_ref7","doi-asserted-by":"publisher","first-page":"3110","DOI":"10.1002\/cncr.30239","article-title":"Diagnostic and treatment strategy for small gastrointestinal stromal tumors","volume":"122","author":"Nishida","year":"2016","journal-title":"Cancer"},{"key":"2025053111170240000_ref8","doi-asserted-by":"publisher","DOI":"10.2147\/btt.s4396","article-title":"Update on the treatment of gastrointestinal stromal tumors (GISTs): role of imatinib","volume":"19","author":"Quek","year":"2010","journal-title":"Biol Targets Therapy"},{"key":"2025053111170240000_ref9","doi-asserted-by":"publisher","first-page":"1052","DOI":"10.1056\/nejm200104053441404","article-title":"Effect of the tyrosine kinase inhibitor STI571 in a patient with a metastatic gastrointestinal stromal tumor","volume":"344","author":"Joensuu","year":"2001","journal-title":"N Engl J Med"},{"key":"2025053111170240000_ref10","doi-asserted-by":"publisher","first-page":"58","DOI":"10.1016\/j.ijscr.2014.12.012","article-title":"Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumor of the small intestine: a case report and a literature review","volume":"6","author":"Alessiani","year":"2015","journal-title":"Int J Surg Case Rep"},{"key":"2025053111170240000_ref11","doi-asserted-by":"publisher","DOI":"10.17235\/reed.2022.8580\/2022","article-title":"Gastric gastrointestinal stromal tumor abscess","volume":"115","author":"Vico","year":"2023","journal-title":"Revista Espanola De Enfermedades Digestivas"},{"key":"2025053111170240000_ref12","doi-asserted-by":"publisher","first-page":"25","DOI":"10.1007\/s12029-013-9528-0","article-title":"Stomach GIST presenting as a liver abscess","volume":"45","author":"Fakhrejahani","year":"2013","journal-title":"J Gastrointest Cancer"},{"key":"2025053111170240000_ref13","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjad427","article-title":"Giant gastric GIST with fast-growing mass after intra-tumoral bleeding","volume":"2023","author":"Duguma","year":"2023","journal-title":"J Surg Case Rep"},{"key":"2025053111170240000_ref14","doi-asserted-by":"publisher","first-page":"1559","DOI":"10.1007\/s00432-019-02853-y","article-title":"Gastrointestinal stromal tumors (GISTs) with remarkable cystic change: a specific subtype of GISTs with relatively indolent behaviors and favorable prognoses","volume":"145","author":"Xue","year":"2019","journal-title":"J Cancer Res Clin Oncol"}],"container-title":["Journal of Surgical Case 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