{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:51:02Z","timestamp":1792605062940,"version":"4.5.0"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T00:00:00Z","timestamp":1749686400000},"content-version":"vor","delay-in-days":12,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Adenomyoepithelioma of the breast (AME) is a rare tumor characterized by a dual proliferation of epithelial and myoepithelial cells. Although typically benign, AME carries a significant risk of recurrence and, in rare cases, malignant transformation. Its rarity, variable imaging features, and histological complexity make diagnosis challenging. Because it can closely mimic invasive breast carcinoma and overlap with other myoepithelial lesions, accurate histopathological assessment is essential. Here, we present the case of a 58-year-old woman with AME diagnosed on mastectomy following an initial misdiagnosis as carcinoma based on biopsy results. We review the literature and highlight the histopathological pitfalls associated with this rare entity.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf372","type":"journal-article","created":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T19:19:41Z","timestamp":1749755981000},"source":"Crossref","is-referenced-by-count":4,"title":["Adenomyoepithelioma of the breast: a challenging diagnosis on biopsy\u2014case report and literature review"],"prefix":"10.1093","volume":"2025","author":[{"given":"Imane","family":"Tazi","sequence":"first","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bouchra","family":"Kouhkouh","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soumaya","family":"Ech-charif","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ismail","family":"Boujida","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mouna","family":"Khmou","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youssef","family":"Mahdi","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Basma","family":"El Khannoussi","sequence":"additional","affiliation":[{"name":"Ibn Sina University Hospital Center Pathology , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]},{"name":"Faculty of Medicine and Pharmacy of Rabat Pathology, Mohammed V University of Rabat , Rabat-Sale-Zemmour-Zaer, Rabat ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,12]]},"reference":[{"key":"2025061215193463700_ref1","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.clinimag.2021.02.002","article-title":"Adenomyoepithelioma of the breast: case series and literature review","volume":"75","author":"Parikh","year":"2021","journal-title":"Clin Imaging"},{"key":"2025061215193463700_ref2","volume-title":"WHO Classification of Tumours: Breast Tumours","author":"WHO Classification of Tumours Editorial Board","edition":"5th ed."},{"key":"2025061215193463700_ref3","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1007\/s004280050145","article-title":"Adenomyoepithelioma of the breast with malignant 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Normal state; regressive changes; hyperplasia; tumors","volume":"53","author":"Hamperl","year":"1970","journal-title":"Curr Top Pathol"},{"key":"2025061215193463700_ref8","doi-asserted-by":"publisher","first-page":"398","DOI":"10.3348\/jksr.2022.0021","article-title":"Benign Adenomyoepithelioma of the breast: imaging characteristics","volume":"84","author":"Shin","year":"2023","journal-title":"J Korean Soc Radiol"},{"key":"2025061215193463700_ref9","doi-asserted-by":"publisher","first-page":"132","DOI":"10.1016\/j.breast.2016.07.018","article-title":"Breast adenomyoepithelioma and adenomyoepithelioma with carcinoma (malignant adenomyoepithelioma) with associated breast malignancies: a case series emphasizing histologic, radiologic, and clinical correlation","author":"Moritz","year":"2016","journal-title":"Breast"},{"key":"2025061215193463700_ref10","doi-asserted-by":"publisher","first-page":"130","DOI":"10.1016\/j.prp.2015.09.008","article-title":"Adenomyoepithelioma with carcinoma of the breast: a report of two cases and a review of the literature","volume":"212","author":"Xu","year":"2016","journal-title":"Pathol Res Pract"},{"key":"2025061215193463700_ref11","doi-asserted-by":"publisher","first-page":"e936070","DOI":"10.12659\/AJCR.936070","article-title":"Adenomyoepithelioma of the breast: a report of 3 cases","volume":"23","author":"AlQurashi","year":"2022","journal-title":"Am J Case Rep"},{"key":"2025061215193463700_ref12","doi-asserted-by":"publisher","first-page":"725","DOI":"10.5858\/arpa.2011-0404-RS","article-title":"Adenomyoepithelioma of the breast: a brief diagnostic review","volume":"137","author":"Yoon","year":"2013","journal-title":"Arch Pathol Lab Med"},{"key":"2025061215193463700_ref13","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1097\/00000478-199106000-00004","article-title":"Myoepithelial lesions of the breast. 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