{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,11]],"date-time":"2025-09-11T21:13:15Z","timestamp":1757625195667,"version":"3.44.0"},"reference-count":17,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T00:00:00Z","timestamp":1757376000000},"content-version":"vor","delay-in-days":8,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Lipomas, benign proliferations of mature adipose tissue, are the most common subcutaneous mesenchymal tumors and typically remain asymptomatic unless they enlarge significantly or involve critical structures. Lipomatosis, the diffuse formation of multiple lipomas, is a rare condition that can affect atypical anatomical sites, posing diagnostic and therapeutic challenges. We present a rare case of a 22-year-old female with diffuse lipomatosis involving the thyroid, axilla, anterior chest, and left breast, presenting with progressive swelling, compressive symptoms, and functional limitations. Imaging and histopathology confirmed benign adipose proliferation without malignancy. Surgical management included total thyroidectomy, level V neck dissection, and excision of 13.57\u00a0kg of lipomatous tissue. Postoperatively, the patient developed a left upper limb deep vein thrombosis (DVT), successfully managed with anticoagulation. Follow-up showed no recurrence or residual lipomatosis. This case highlights the unusual presentation of extensive lipomatosis involving the thyroid and emphasizes the need for thorough diagnostic workup and careful surgical planning to optimize patient outcomes.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf378","type":"journal-article","created":{"date-parts":[[2025,9,9]],"date-time":"2025-09-09T17:30:26Z","timestamp":1757439026000},"source":"Crossref","is-referenced-by-count":0,"title":["Chest wall and axillary lipomatosis in association with cystic hygroma, thyroid nodules, and vascular complications\u2014a comprehensive case study"],"prefix":"10.1093","volume":"2025","author":[{"given":"Abdulaziz S","family":"AlQahtani","sequence":"first","affiliation":[{"name":"College of Medicine, King Saud University , PO Box 2925, Riyadh 11461 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saleh Husam","family":"Aldeligan","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University , PO Box 2925, Riyadh 11461 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdulaziz Abdulmuhsin","family":"Alqusiyer","sequence":"additional","affiliation":[{"name":"College of Medicine, King Saud University , PO Box 2925, Riyadh 11461 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Aljunaydil","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University Medical City , PO Box 2925, Riyadh 11461 ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Budur T","family":"Althobaiti","sequence":"additional","affiliation":[{"name":"Al Hada Armed Forces Hospital, Department of Surgery , Taif ,","place":["Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Areej","family":"Bokhari","sequence":"additional","affiliation":[{"name":"Department of Surgery, King Saud University , Riyadh ,","place":["Kingdom of Saudi Arabia"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,9]]},"reference":[{"key":"2025090913301759900_ref1","volume-title":"Lipomas : Review and Evaluat\u0131on of the Literature","author":"Der\u0131n","year":"2017"},{"key":"2025090913301759900_ref2","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1046\/J.1524-4725.2003.29052.X","article-title":"Post traumatic lipoma: analysis of 10 cases and explanation of possible mechanisms","volume":"29","author":"\u00c7opcu","year":"2003","journal-title":"Dermatol Surg"},{"key":"2025090913301759900_ref3","doi-asserted-by":"publisher","first-page":"57","DOI":"10.1016\/0092-8674(95)90052-7","article-title":"Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory 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