{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,30]],"date-time":"2025-07-30T12:07:32Z","timestamp":1753877252445,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T00:00:00Z","timestamp":1749427200000},"content-version":"vor","delay-in-days":9,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Colorectal carcinoma with a finding of isolated brain metastasis is rare. Furthermore, neurologic symptoms secondary to oligometastasis to the brain are very rare initial presentations for colorectal cancer. Hence, it is uncommon to do brain imaging in the initial staging of colon carcinoma. We present an unusual case of a patient who initially presented with a headache. Laboratory tests revealed mild anemia. Brain imaging revealed a mass in the parietal lobe; hence, neurosurgery was performed with resection of the mass. Histopathology showed it\u2019s colonic in origin. Colonoscopy revealed adenocarcinoma in the sigmoid colon and a staging computed tomography scan showed no distant metastases. This case report highlights the unusual presentation of an isolated brain metastasis secondary to primary colon carcinoma. Any patient with a primary colon tumor who complains of neurologic symptoms should be considered for brain evaluation to minimize the risk of overlooking such important finding.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf394","type":"journal-article","created":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T04:41:43Z","timestamp":1749444103000},"source":"Crossref","is-referenced-by-count":0,"title":["An unusual case of isolated brain metastasis with impending brain herniation from sigmoid colon cancer: case report and review of literature"],"prefix":"10.1093","volume":"2025","author":[{"given":"Ali","family":"Toffaha","sequence":"first","affiliation":[{"name":"Department of Surgery, Colorectal Surgery Unit, Hamad General Hospital , Alrayyan Road, PO Box 3050, Doha ,","place":["Qatar"]},{"name":"College of Medicine, QU Health, Qatar University , Alrayyan Road, PO Box 3050, Doha ,","place":["Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hafiz Bilal","family":"Zafar","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Hamad General Hospital , Doha , Alrayyan Road, PO Box 3050, Doha ,","place":["Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamza A","family":"Abdul-Hafez","sequence":"additional","affiliation":[{"name":"Department of Medicine, Faculty of Medicine and Health Sciences, An-Najah National University , Rafidia Road, PO Box 7, Nablus ,","place":["Palestine"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmood","family":"Al-Dhaheri","sequence":"additional","affiliation":[{"name":"Department of Surgery, Colorectal Surgery Unit, Hamad General Hospital , Alrayyan Road, PO Box 3050, Doha ,","place":["Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed","family":"Abunada","sequence":"additional","affiliation":[{"name":"Department of Surgery, Colorectal Surgery Unit, Hamad General Hospital , Alrayyan Road, PO Box 3050, Doha ,","place":["Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amjad","family":"Parvaiz","sequence":"additional","affiliation":[{"name":"Department of Surgery, Colorectal Surgery Unit, Hamad General Hospital , Alrayyan Road, PO Box 3050, Doha ,","place":["Qatar"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,6,9]]},"reference":[{"volume-title":"Colorectal Cancer\u2014Cancer Stat Facts","year":"2020","key":"2025060900413731300_ref1"},{"key":"2025060900413731300_ref2","doi-asserted-by":"crossref","first-page":"3039","DOI":"10.1111\/j.1572-0241.1999.01454.x","article-title":"How does colorectal cancer present? 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Is the resection of the primary non-complicated tumour indicated when the metastases have been resected?","volume":"12","author":"Ruiz-Tovar","year":"2010","journal-title":"Clin Transl Oncol"},{"key":"2025060900413731300_ref14","doi-asserted-by":"publisher","first-page":"13","DOI":"10.4274\/mirt.29491","article-title":"A case of primary colon carcinoma demonstrated by FDG PET\/CT imaging after detection of a solitary brain metastasis","volume":"24","author":"Erhamamc\u0131","year":"2015","journal-title":"Mal Imaging Radionucl Ther"},{"key":"2025060900413731300_ref15","first-page":"1245","article-title":"Colorectal carcinoma with hemiparesis due to isolated brain metastases as an initial symptom\u2014a case report","volume":"41","author":"Goto","year":"2014","journal-title":"Gan To Kagaku Ryoho"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/6\/rjaf394\/63451974\/rjaf394.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/6\/rjaf394\/63451974\/rjaf394.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,9]],"date-time":"2025-06-09T04:41:44Z","timestamp":1749444104000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf394\/8158420"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,31]]},"references-count":15,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf394","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2025,5,31]]},"article-number":"rjaf394"}}