{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T13:40:01Z","timestamp":1752327601049,"version":"3.41.2"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T00:00:00Z","timestamp":1752278400000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Oropharyngeal squamous cell carcinoma (OPSCC) commonly metastasizes to the lungs, bones, and distant lymph nodes. Liver metastases from OPSCC are rare and typically occur in advanced stages. We present a 59-year-old male diagnosed with OPSCC, initially treated with surgery followed by adjuvant radiotherapy (RDT). Due to political and governmental limitations, the patient received only six sessions of RDT, below the standard recommended regimen. Three years post-treatment, he presented with abdominal symptoms, and imaging revealed a hepatic lesion. A liver biopsy confirmed metastatic squamous cell carcinoma. Histopathological comparison with the primary tumor supported the diagnosis of hepatic metastasis from OPSCC. This case underscores the aggressive nature of OPSCC and the critical importance of completing multimodal therapy. Interrupted adjuvant treatment may have contributed to early distant spread. While liver metastases from OPSCC are rare, they should be considered in patients presenting with compatible symptoms and a history of incomplete treatment.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf417","type":"journal-article","created":{"date-parts":[[2025,7,12]],"date-time":"2025-07-12T13:10:49Z","timestamp":1752325849000},"source":"Crossref","is-referenced-by-count":0,"title":["Liver metastases from oropharyngeal squamous cell carcinoma: a rare case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Daniel","family":"Solis-Pazmino","sequence":"first","affiliation":[{"name":"Department of Oral and Maxillofacial Surgery, Pontifical Catholic University of Rio Grande do Sul (PUCRS) , Avenida Ipiranga, 6681 Parten\u00f3n, Porto Alegre, RS 90619-900 ,","place":["Brazil"]},{"name":"CaTaLiNA- Cancer de Tiroides en Latino Am\u00e9rica , Quito ,","place":["Ecuador"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberta","family":"Baldin","sequence":"additional","affiliation":[{"name":"Department of General Surgery , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]},{"name":"Santa Casa de Miseric\u00f3rdia de Porto Alegre , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Magno","family":"Guar\u00e7oni","sequence":"additional","affiliation":[{"name":"Department of General Surgery , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]},{"name":"Santa Casa de Miseric\u00f3rdia de Porto Alegre , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Bertinatto","sequence":"additional","affiliation":[{"name":"Department of General Surgery , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]},{"name":"Santa Casa de Miseric\u00f3rdia de Porto Alegre , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Maldonado","sequence":"additional","affiliation":[{"name":"Department of General Surgery , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]},{"name":"Santa Casa de Miseric\u00f3rdia de Porto Alegre , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 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Casa de Miseric\u00f3rdia de Porto Alegre , , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paola","family":"Solis-Pazmino","sequence":"additional","affiliation":[{"name":"CaTaLiNA- Cancer de Tiroides en Latino Am\u00e9rica , Quito ,","place":["Ecuador"]},{"name":"Department of General Surgery, Santa Casa de Miseric\u00f3rdia de Porto Alegre , Rua Professor Annes Dias, 295 Centro Hist\u00f3rico, Porto Alegre, RS 90020-090 ,","place":["Brazil"]},{"name":"Surgery Group Los Angeles , 8635 W 3rd St Suite 880W, Los Angeles, CA 90048 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,7,12]]},"reference":[{"key":"2025071209104174000_ref1","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1016\/J.SOC.2015.03.001","article-title":"Epidemiology of head and neck 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