{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T10:31:33Z","timestamp":1785148293768,"version":"3.55.0"},"reference-count":9,"publisher":"Oxford University Press (OUP)","issue":"6","license":[{"start":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T00:00:00Z","timestamp":1750032000000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,31]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ankylosing spondylitis is a chronic inflammatory spondyloarthropathy that will cause severe symptoms and complications if left untreated. Anti-TNF-\u03b1 inhibitor is the treatment of choice, yet\u00a0all treatments have difficulties, and opportunistic infections following this therapy are well known. Reactivation of latent tuberculosis (TB) and abdominal TB is a serious problem in this therapy since diagnosis is difficult, as symptoms are nonspecific, and complications can be fatal. We present the case of a 47-year-old female doctor with a past medical history of ankylosing spondylitis; she was treated with infliximab. She began developing abdominal pain that led to an acute abdomen due to abdominal TB. After successful treatment, she fully recovered, and the patient is doing well in follow-ups.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf422","type":"journal-article","created":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T11:11:35Z","timestamp":1750072295000},"source":"Crossref","is-referenced-by-count":1,"title":["Abdominal tuberculosis in a patient with ankylosing spondylitis and infliximab: is the risk still too great? A case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Miguel \u00c1ngel","family":"Moy\u00f3n","sequence":"first","affiliation":[{"name":"Department of General Surgery , Cl\u00ednica Pasteur & School of Medicine, , Av. Eloy Alfaro, N29-248, Quito 170515 ,","place":["Ecuador"]},{"name":"Pontificia Universidad Cat\u00f3lica del Ecuador (PUCE) , Cl\u00ednica Pasteur & School of Medicine, , Av. Eloy Alfaro, N29-248, Quito 170515 ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan Stephany","family":"A\u00f1azco","sequence":"additional","affiliation":[{"name":"Department of General Surgery, Cl\u00ednica Pasteur , Av. Eloy Alfaro, N29-248, Quito 170515 ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex Enrique","family":"V\u00e1sconez","sequence":"additional","affiliation":[{"name":"Department of Oncology, Cl\u00ednica Pasteur , ,","place":["Ecuador"]},{"name":"Av. Eloy Alfaro, N29-248, Quito 170515 , ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Larreategui","sequence":"additional","affiliation":[{"name":"Division of Infectology, Department of Internal Medicine, Cl\u00ednica Pasteur , ,","place":["Ecuador"]},{"name":"Av. Eloy Alfaro, N29-248, Quito 170515 , ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda Bel\u00e9n","family":"Torres","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Internal Medicine, Cl\u00ednica Pasteur , ,","place":["Ecuador"]},{"name":"Av. Eloy Alfaro, N29-248, Quito 170515 , ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natali","family":"Moy\u00f3n","sequence":"additional","affiliation":[{"name":"Department of Anaesthesiology, Cl\u00ednica Pasteur , ,","place":["Ecuador"]},{"name":"Av. Eloy Alfaro, N29-248, Quito 170515 , ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tatiana","family":"Borja","sequence":"additional","affiliation":[{"name":"Department of Pathology, Vida Pathology , ,","place":["Ecuador"]},{"name":"Av. Mariana de Jes\u00fas OE7-02 y Nu\u00f1o de Valderama Citimed, Quito 170509 , ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0001-9070","authenticated-orcid":false,"given":"Gabriel Alejandro","family":"Molina","sequence":"additional","affiliation":[{"name":"Universidad San Francisco de Quito (USFQ), Department of General Surgery Hospital IESS Quito Sur , ,","place":["Ecuador"]},{"name":"Diego de Robles s\/n, Quito 170901 , ,","place":["Ecuador"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,6,16]]},"reference":[{"key":"2025061607112491200_ref1","doi-asserted-by":"publisher","first-page":"802298","DOI":"10.3389\/fped.2021.802298","article-title":"Development of spinal tuberculosis in an adolescent with Crohn's disease after infliximab therapy: a case report with literature review","volume":"9","author":"Jung","year":"2022","journal-title":"Front Pediatr"},{"key":"2025061607112491200_ref2","doi-asserted-by":"publisher","first-page":"e17652","DOI":"10.1097\/MD.0000000000017652","article-title":"Ulcerative intestinal tuberculosis case as a complication of treatment by infliximab for intestinal Beh\u00e7et's disease: a case report","volume":"98","author":"Shen","year":"2019","journal-title":"Medicine"},{"key":"2025061607112491200_ref3","doi-asserted-by":"publisher","first-page":"e2436","DOI":"10.1097\/MD.0000000000002436","article-title":"Misdiagnosis and mistherapy of Crohn's disease as intestinal tuberculosis: case report and literature review","volume":"95","author":"Wei","year":"2016","journal-title":"Medicine"},{"key":"2025061607112491200_ref4","doi-asserted-by":"publisher","first-page":"41","DOI":"10.4103\/jpp.JPP_174_16","article-title":"Pleural tuberculosis following infliximab therapy for ankylosing spondylitis","volume":"8","author":"Krishnan","year":"2017","journal-title":"J Pharmacol Pharmacother"},{"key":"2025061607112491200_ref5","doi-asserted-by":"publisher","first-page":"CD005468","DOI":"10.1002\/14651858.CD005468.pub2","article-title":"TNF-alpha inhibitors for ankylosing spondylitis","volume":"2015","author":"Maxwell","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"2025061607112491200_ref9","doi-asserted-by":"publisher","first-page":"1439","DOI":"10.1007\/s10067-019-04866-x","article-title":"Incidence of tuberculosis in patients receiving anti-TNF therapy for rheumatic diseases: a systematic review","volume":"39","author":"Sartori","year":"2020","journal-title":"Clinical Rheumatology"},{"key":"2025061607112491200_ref6","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000000527","article-title":"Risk of tuberculosis in patients with inflammatory bowel disease on infliximab or adalimumab is dependent on the local disease burden of tuberculosis","volume":"115","author":"Kedia","year":"2020","journal-title":"Am J Gastroenterol"},{"key":"2025061607112491200_ref7","doi-asserted-by":"publisher","first-page":"588","DOI":"10.5217\/ir.2018.00023","article-title":"High risk of tuberculosis during infliximab therapy despite tuberculosis screening in inflammatory bowel disease patients in India","volume":"16","author":"Agarwal","year":"2018","journal-title":"Intestinal Res"},{"key":"2025061607112491200_ref8","doi-asserted-by":"publisher","first-page":"374","DOI":"10.5606\/tftrd.2021.5135","article-title":"A rare localization of tuberculosis under infliximab treatment: testicular involvement","volume":"67","author":"Nay\u0131mo\u011flu","year":"2021","journal-title":"Turk J Phys Med Rehabil"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/6\/rjaf422\/63498263\/rjaf422.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/6\/rjaf422\/63498263\/rjaf422.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,16]],"date-time":"2025-06-16T11:11:35Z","timestamp":1750072295000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf422\/8163647"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,31]]},"references-count":9,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2025,5,31]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf422","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,6]]},"published":{"date-parts":[[2025,5,31]]},"article-number":"rjaf422"}}