{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T03:46:57Z","timestamp":1792813617075,"version":"4.5.0"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T00:00:00Z","timestamp":1752451200000},"content-version":"vor","delay-in-days":13,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Angioleiomyoma is a rare benign vascular smooth muscle tumor, exceptionally reported in the orbit and peri-orbital region with fewer than 25 cases documented. We report a case of a 60-year-old male presenting a slowly progressive, painless lower eyelid mass evolving over 10\u00a0years. Clinical examination revealed a well-circumscribed 15\u00a0mm lesion. Angio-computed tomography (CT) demonstrated a 22\u2009\u00d7\u200924\u2009\u00d7\u200918\u00a0mm well-circumscribed mass with peripheral contrast enhancement, consistent with a vascularized lesion. Surgical excision via a subciliary approach was performed. Histopathological analysis showed a 15\u2009\u00d7\u200910\u00a0mm tumor composed of smooth muscle bundles surrounding vascular channels. Immunohistochemistry was positive for smooth muscle actin and desmin, confirming the diagnosis of angioleiomyoma. No recurrence was observed during a 3-year follow-up. The absence of magnetic resonance imaging (MRI), due to patient financial constraints, constitutes a limitation discussed herein. This case highlights the diagnostic challenge and the importance of considering angioleiomyoma in differential diagnoses of eyelid masses.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf507","type":"journal-article","created":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T12:34:06Z","timestamp":1752496446000},"source":"Crossref","is-referenced-by-count":1,"title":["Lower eyelid angioleiomyoma: a rare case of a slowly progressive orbital tumor with a 10-year history"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-9891-7939","authenticated-orcid":false,"given":"Amine","family":"Oussalem","sequence":"first","affiliation":[{"name":"Speciality Hospital, Department of Maxillo-Facial Surgery, Area Lamfadel Cherkaoui , Rabat - Institut, Rabat B.P 6527 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anas","family":"Azgaoui","sequence":"additional","affiliation":[{"name":"Speciality Hospital, Department of Maxillo-Facial Surgery, Area Lamfadel Cherkaoui , Rabat - Institut, Rabat B.P 6527 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3344-421X","authenticated-orcid":false,"given":"Bouchra","family":"Dani","sequence":"additional","affiliation":[{"name":"Speciality Hospital, Department of Maxillo-Facial Surgery, Area Lamfadel Cherkaoui , Rabat - Institut, Rabat B.P 6527 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0351-0597","authenticated-orcid":false,"given":"Malik","family":"Boulaadas","sequence":"additional","affiliation":[{"name":"Speciality Hospital, Department of Maxillo-Facial Surgery, Area Lamfadel Cherkaoui , Rabat - Institut, Rabat B.P 6527 ,","place":["Morocco"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,7,14]]},"reference":[{"key":"2025071408340265600_ref1","first-page":"234","article-title":"Orbital angioleiomyoma: a review of less than 25 cases","volume":"34","author":"Smith","year":"2018","journal-title":"Ophthalmic Plast Reconstr Surg"},{"key":"2025071408340265600_ref2","first-page":"115","article-title":"Periorbital angioleiomyoma: clinical and imaging features","volume":"40","author":"Doe","year":"2021","journal-title":"Orbit."},{"key":"2025071408340265600_ref3","first-page":"945670","article-title":"Painful orbital angioleiomyoma with proptosis","volume":"2019","author":"Min","year":"2019","journal-title":"J Ophthalmol"},{"key":"2025071408340265600_ref4","first-page":"45","article-title":"Imaging features of angioleiomyoma: diagnostic utility of contrast-enhanced MRI and CT","volume":"38","author":"Yamaguchi","year":"2020","journal-title":"Jpn J Radiol"},{"key":"2025071408340265600_ref5","first-page":"435","article-title":"MRI characteristics of orbital vascular tumors","volume":"52","author":"Lee","year":"2017","journal-title":"Invest Radiol"},{"key":"2025071408340265600_ref6","first-page":"1285","article-title":"Discrepancies in tumor size assessments across modalities in vascular tumors","volume":"71","author":"Patel","year":"2016","journal-title":"Clin Radiol"},{"key":"2025071408340265600_ref7","first-page":"442","article-title":"Immunohistochemical profile of angioleiomyoma and differential diagnoses","volume":"66","author":"Zhang","year":"2015","journal-title":"Histopathology"},{"key":"2025071408340265600_ref8","first-page":"876","article-title":"Long-term outcomes after excision of orbital angioleiomyoma","volume":"36","author":"Chen","year":"2022","journal-title":"Eye"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/7\/rjaf507\/63747026\/rjaf507.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/7\/rjaf507\/63747026\/rjaf507.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,14]],"date-time":"2025-07-14T12:34:06Z","timestamp":1752496446000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf507\/8199761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7]]},"references-count":8,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025,7,2]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf507","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,7]]},"published":{"date-parts":[[2025,7]]},"article-number":"rjaf507"}}