{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,21]],"date-time":"2025-08-21T18:42:23Z","timestamp":1755801743329,"version":"3.44.0"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":19,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>This case report demonstrates two contrasting clinical cases of patients with early-stage endometrial cancer undergoing sentinel lymph node (SLN) mapping. In the first case, a 68-year-old patient with a body mass index (BMI) of 38 underwent SLN mapping using indocyanine green (ICG) alone. Although fluorescence-guided dissection revealed nodes appearing \u201cICG-positive,\u201d histopathological evaluation confirmed the absence of lymphatic tissue in the removed specimens\u2014indicating the presence of so-called \u201cempty nodes.\u201d This highlights the limitations of relying solely on optical fluorescence, especially in patients with high BMI or altered lymphatic architecture. In contrast, the second case, involving a 65-year-old patient with a BMI of 40, demonstrates the effectiveness of using a combined technique with ICG and technetium-99m (Tc99m). The synergy between real-time fluorescence visualization and gamma probe detection enabled precise SLN identification and confirmed the presence of true lymphatic tissue histologically. This dual case report underscores the limitations of ICG-only SLN mapping and and illustrates the potential added value of technetium-99m in improving the accuracy of lymphatic staging, warranting further validation.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf508","type":"journal-article","created":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T18:04:13Z","timestamp":1755713053000},"source":"Crossref","is-referenced-by-count":0,"title":["False detection and the value of combined tracer mapping in endometrial cancer: a dual case presentation"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7682-7176","authenticated-orcid":false,"given":"Wiktor","family":"Szatkowski","sequence":"first","affiliation":[{"name":"Department of Gynecological Oncology, Maria Sk\u0142odowska-Curie National Research Institute , Garncarska 11, 31-115 Krakow ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karolina","family":"Pniewska","sequence":"additional","affiliation":[{"name":"Department of Gynecological Oncology, Maria Sk\u0142odowska-Curie National Research Institute , Garncarska 11, 31-115 Krakow ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pawe\u0142","family":"Blecharz","sequence":"additional","affiliation":[{"name":"Department of Gynecological Oncology, Maria Sk\u0142odowska-Curie National Research Institute , Garncarska 11, 31-115 Krakow ,","place":["Poland"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"2025082014040653100_ref1","doi-asserted-by":"publisher","first-page":"843","DOI":"10.1016\/j.ejso.2014.02.228","article-title":"Indocyanine green fluorescence-guided sentinel node biopsy: a meta-analysis on detection rate and diagnostic performance","volume":"40","author":"Xiong","year":"2014","journal-title":"Eur J Surg Oncol"},{"key":"2025082014040653100_ref2","doi-asserted-by":"publisher","first-page":"267","DOI":"10.1016\/j.ygyno.2018.06.001","article-title":"Tips and tricks to improve sentinel lymph node mapping with indocyanin green in endometrial cancer","volume":"150","author":"Body","year":"2018","journal-title":"Gynecol Oncol"},{"key":"2025082014040653100_ref3","doi-asserted-by":"publisher","first-page":"120","DOI":"10.1016\/j.ygyno.2017.07.131","article-title":"Description of a reproducible anatomically based surgical algorithm for detection of pelvic sentinel lymph nodes in endometrial cancer","volume":"147","author":"Persson","year":"2017","journal-title":"Gynecol Oncol"},{"key":"2025082014040653100_ref4","doi-asserted-by":"publisher","first-page":"676","DOI":"10.3390\/jcm14030676","article-title":"The assessment of sentinel lymph node mapping methods in endometrial cancer","volume":"14","author":"Szatkowski","year":"2025","journal-title":"J Clin Med"},{"key":"2025082014040653100_ref5","doi-asserted-by":"publisher","first-page":"436","DOI":"10.1016\/j.ygyno.2015.04.004","article-title":"Comparing indocyanine green, technetium, and blue dye for sentinel lymph node mapping in endometrial cancer","volume":"137","author":"How","year":"2015","journal-title":"Gynecol Oncol"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/8\/rjaf508\/64096248\/rjaf508.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/8\/rjaf508\/64096248\/rjaf508.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T18:04:13Z","timestamp":1755713053000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf508\/8238765"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":5,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf508","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,8]]},"published":{"date-parts":[[2025,8]]},"article-number":"rjaf508"}}