{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T16:06:53Z","timestamp":1789142813370,"version":"build-2803163510"},"reference-count":13,"publisher":"Oxford University Press (OUP)","issue":"7","license":[{"start":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T00:00:00Z","timestamp":1752710400000},"content-version":"vor","delay-in-days":16,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,7,2]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Castleman's disease is a rare, benign lymphoproliferative disorder that can occur in various anatomical sites, including the retroperitoneum. Unicentric Castleman disease (UCD), particularly the hyaline vascular variant, often presents as a solitary mass and can mimic malignancy. We reported a case of a 53-year-old man presenting with urinary hesitancy for 3\u00a0months. Imaging studies identified a well-defined, hypervascular retroperitoneal mass located anterior to the abdominal aorta and posterior to the pancreas. Endoscopic ultrasound with biopsy was performed, but the results were inconclusive and did not provide the necessary clarity for a definitive diagnosis. Surgical excision was performed, and histopathological examination confirmed a hyaline vascular variant of UCD. This case highlights the diagnostic challenge of retroperitoneal UCD and under-scores the essential role of histopathology in distinguishing it from malignancy. Complete surgical resection is curative, and early recognition can prevent unnecessary delays in management.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf543","type":"journal-article","created":{"date-parts":[[2025,7,17]],"date-time":"2025-07-17T02:45:35Z","timestamp":1752720335000},"source":"Crossref","is-referenced-by-count":2,"title":["Retroperitoneal unicentric hyaline vascular variant of Castleman\u2019s disease: a case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Khanh C","family":"Pham","sequence":"first","affiliation":[{"name":"Gastrointestinal Endoscopy and Laparoscopic Surgery Center, Tam Anh General Hospital , 2B Pho Quang Street, Tan Binh District, Ho Chi Minh City 70000 ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thuy M","family":"Le","sequence":"additional","affiliation":[{"name":"Gastrointestinal Endoscopy and Laparoscopic Surgery Center, Tam Anh General Hospital , 2B Pho Quang Street, Tan Binh District, Ho Chi Minh City 70000 ,","place":["Vietnam"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,7,17]]},"reference":[{"key":"2025071622453127200_ref1","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1097\/SLA.0b013e318249dcdc","article-title":"Surgery in Castleman's disease: a systematic review of 404 published cases","volume":"255","author":"Talat","year":"2012","journal-title":"Ann Surg"},{"key":"2025071622453127200_ref2","doi-asserted-by":"publisher","first-page":"1646","DOI":"10.1182\/blood-2016-10-746933","article-title":"International, evidence-based consensus diagnostic criteria for HHV-8-negative\/idiopathic multicentric Castleman disease","volume":"129","author":"Fajgenbaum","year":"2017","journal-title":"Blood"},{"key":"2025071622453127200_ref3","doi-asserted-by":"publisher","first-page":"37","DOI":"10.1016\/j.hoc.2017.09.004","article-title":"Pathology of Castleman disease","volume":"32","author":"Wu","year":"2018","journal-title":"Hematol Oncol Clin North Am"},{"key":"2025071622453127200_ref4","doi-asserted-by":"publisher","first-page":"e9939","DOI":"10.1097\/MD.0000000000009939","article-title":"Castleman disease in the hilum liver mimicking the lymph node metastasis of hepatocellular carcinoma on 18F-FDG PET\/CT: a case report","volume":"97","author":"Hu","year":"2018","journal-title":"Medicine"},{"key":"2025071622453127200_ref5","doi-asserted-by":"publisher","first-page":"105650","DOI":"10.1016\/j.ijscr.2021.105650","article-title":"Castleman disease: a single-center case series","volume":"80","author":"Pribyl","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"2025071622453127200_ref6","doi-asserted-by":"publisher","first-page":"e20102","DOI":"10.1097\/MD.0000000000020102","article-title":"Ultrasound and radiological features of abdominal unicentric castleman's disease: a case series study","volume":"99","author":"Lv","year":"2020","journal-title":"Medicine"},{"key":"2025071622453127200_ref7","doi-asserted-by":"publisher","first-page":"1250","DOI":"10.1007\/s12328-021-01418-2","article-title":"Unicentric Castleman's disease of hepatic hilum and retroperitoneum: a case report for endoscopic ultrasonography differential diagnosis and a literature review","volume":"14","author":"Yin","year":"2021","journal-title":"Clin J Gastroenterol"},{"key":"2025071622453127200_ref8","doi-asserted-by":"publisher","DOI":"10.1055\/s-0030-1256163","article-title":"A rare case of peripancreatic Castleman's disease diagnosed preoperatively by endoscopic ultrasound-guided fine needle aspiration","volume":"43","author":"Khashab","year":"2011","journal-title":"Endoscopy"},{"key":"2025071622453127200_ref9","doi-asserted-by":"publisher","first-page":"106325","DOI":"10.1016\/j.ijscr.2021.106325","article-title":"Retroperitoneal unicentric Castleman's disease-a case report and review of literature","volume":"86","author":"Singh","year":"2021","journal-title":"Int J Surg Case Rep"},{"key":"2025071622453127200_ref10","doi-asserted-by":"publisher","first-page":"2123","DOI":"10.3892\/ol.2016.4177","article-title":"Surgical management of isolated retroperitoneal Castleman's disease: a case report","volume":"11","author":"Xu","year":"2016","journal-title":"Oncol Lett"},{"key":"2025071622453127200_ref11","doi-asserted-by":"publisher","first-page":"209","DOI":"10.1016\/j.dld.2023.09.022","article-title":"EUS guided fine needle biopsy in the diagnosis of pancreatic Castleman disease (with video)","volume":"56","author":"Shi","year":"2024","journal-title":"Dig Liver Dis"},{"key":"2025071622453127200_ref12","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1186\/s12957-015-0756-6","article-title":"Clinicopathological characteristics of unicentric retroperitoneal Castleman's disease: a study of 14 cases","volume":"14","author":"Wang","year":"2016","journal-title":"World J Surg Oncol"},{"key":"2025071622453127200_ref13","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1186\/1477-7819-12-30","article-title":"Retroperitoneal Castleman's disease: advocating a multidisciplinary approach for a rare clinical entity","volume":"12","author":"Williams","year":"2014","journal-title":"World J Surg Oncol"}],"container-title":["Journal of Surgical Case 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