{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T00:13:58Z","timestamp":1755216838935,"version":"3.43.0"},"reference-count":10,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T00:00:00Z","timestamp":1754265600000},"content-version":"vor","delay-in-days":3,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Low anterior resection syndrome (LARS) is a frequent problem encountered by patients after rectal cancer surgery, significantly affecting quality of life. Though transanal irrigation (TAI) is an effective management option for LARS symptoms, the treatment can still cause rare but severe complications, such as bowel perforation. We present a very rare case of a 78-year-old patient who developed a bowel perforation after 13 years of regular TAI. Gluteal pain, swelling, and purulent discharge were observed as presenting symptoms. Imaging and clinical examination revealed a perforated blind-ended bowel segment and a communicating abscess in the buttock. Urgent abscess drainage was performed, followed by an intersphincteric abdominoperineal excision and vacuum-assisted wound management (negative-pressure wound therapy). This case highlights the importance of long-term vigilance in patients using TAI, regardless of duration of use. Ongoing patient education, correct technique, and regular follow-up are essential to minimize risks and enable early detection of complications. Teaching patients how to care for themselves, using the right methods, and checking regularly are needed to control risks and see issues right away.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf588","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T21:34:56Z","timestamp":1754343296000},"source":"Crossref","is-referenced-by-count":0,"title":["Bowel perforation following transanal irrigation in low anterior resection syndrome"],"prefix":"10.1093","volume":"2025","author":[{"given":"Ahmed Nameer","family":"Sami","sequence":"first","affiliation":[{"name":"Gastrointestinal Surgical Department, Slagelse Hospital , F\u00e6lledvej 11, 4200 Slagelse ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sharaf Karim","family":"Perdawood","sequence":"additional","affiliation":[{"name":"Gastrointestinal Surgical Department, Slagelse Hospital , F\u00e6lledvej 11, 4200 Slagelse ,","place":["Denmark"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,8,4]]},"reference":[{"key":"2025080417345446400_ref1","doi-asserted-by":"publisher","first-page":"778","DOI":"10.3390\/cancers15030778","article-title":"Management of low anterior resection syndrome (LARS) following resection for rectal cancer","volume":"15","author":"Rosen","year":"2023","journal-title":"Cancers"},{"key":"2025080417345446400_ref2","doi-asserted-by":"publisher","first-page":"1527","DOI":"10.3390\/jcm13061527","article-title":"The functional implications of transanal irrigation: insights from pathophysiology and clinical studies of neurogenic bowel dysfunction","volume":"13","author":"Rodriguez","year":"2024","journal-title":"J Clin Med"},{"key":"2025080417345446400_ref3","doi-asserted-by":"publisher","first-page":"7249","DOI":"10.1007\/s00520-021-06326-2","article-title":"The incidence and risk factors of low anterior resection syndrome (LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis","volume":"29","author":"Sun","year":"2021","journal-title":"Support Care Cancer"},{"key":"2025080417345446400_ref4","first-page":"15","article-title":"Global audit on bowel perforations related to transanal irrigation","volume":"20","author":"Christensen","year":"2015","journal-title":"Tech Coloproctol"},{"key":"2025080417345446400_ref5","doi-asserted-by":"publisher","first-page":"753","DOI":"10.3390\/jcm10040753","article-title":"Transanal irrigation for neurogenic bowel disease, low anterior resection syndrome, faecal incontinence and chronic constipation: a systematic review","volume":"10","author":"Mekhael","year":"2021","journal-title":"J Clin Med"},{"key":"2025080417345446400_ref6","doi-asserted-by":"publisher","first-page":"409","DOI":"10.3390\/std13040033","article-title":"Transanal irrigation in patients with low anterior resection syndrome after rectal-sphincter-preserving surgery for oncological and non-oncological disease: a systematic review","volume":"13","author":"Morini","year":"2024","journal-title":"Surg Tech Dev"},{"key":"2025080417345446400_ref7","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1016\/j.jpurol.2009.07.004","article-title":"Transanal irrigation for the treatment of neuropathic bowel dysfunction","volume":"6","author":"Pereira","year":"2009","journal-title":"J Pediatr Urol"},{"key":"2025080417345446400_ref8","doi-asserted-by":"publisher","first-page":"1267","DOI":"10.1111\/codi.16518","article-title":"Transanal irrigation is a better choice for bowel dysfunction in adults with spina bifida: a randomised controlled trial","volume":"25","author":"Brochard","year":"2023","journal-title":"Colorectal Dis"},{"key":"2025080417345446400_ref9","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1007\/s00464-021-09002-y","article-title":"Risk factors for low anterior resection syndrome (LARS) in patients undergoing laparoscopic surgery for rectal cancer","volume":"36","author":"Nicotera","year":"2022","journal-title":"Surg Endosc"},{"key":"2025080417345446400_ref10","doi-asserted-by":"publisher","first-page":"825","DOI":"10.1007\/s13304-025-02184-3","article-title":"A systematic review of preoperative radiological factors associated with the development of low anterior resection syndrome (LARS)","volume":"77","author":"Gravante","year":"2025","journal-title":"Updates Surg"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/8\/rjaf588\/63947162\/rjaf588.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/8\/rjaf588\/63947162\/rjaf588.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T21:34:57Z","timestamp":1754343297000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf588\/8221978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":10,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf588","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,8]]},"published":{"date-parts":[[2025,8]]},"article-number":"rjaf588"}}