{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,15]],"date-time":"2025-08-15T02:26:12Z","timestamp":1755224772884,"version":"3.43.0"},"reference-count":7,"publisher":"Oxford University Press (OUP)","issue":"8","license":[{"start":{"date-parts":[[2025,8,12]],"date-time":"2025-08-12T00:00:00Z","timestamp":1754956800000},"content-version":"vor","delay-in-days":11,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,8,3]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Here, we report the case of a 53-year-old male patient with hereditary spherocytosis (HS) and a 10-year course of disease, presenting with fatigue, jaundice, abdominal discomfort, massive splenomegaly (spleen size: 35\u2009\u00d7\u200920\u2009\u00d7\u200910\u00a0cm, weight: 10\u00a0kg), and cholelithiasis. The patient had a positive family history, with his father and daughter exhibiting similar symptoms. Combined splenectomy and cholecystectomy significantly alleviated hemolytic jaundice, anemia, and gallstone-related symptoms. HS is an autosomal dominant disorder affecting erythrocyte membranes. Splenectomy effectively improves hemolytic anemia, while concurrent cholecystectomy is necessary to comprehensively manage cholelithiasis. This case highlights the clinical value of combined surgery for HS-related complications, emphasizing that personalized comprehensive treatment optimizes prognosis.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf602","type":"journal-article","created":{"date-parts":[[2025,7,19]],"date-time":"2025-07-19T11:57:30Z","timestamp":1752926250000},"source":"Crossref","is-referenced-by-count":0,"title":["A case report of hereditary spherocytosis complicated by massive splenomegaly and cholelithiasis"],"prefix":"10.1093","volume":"2025","author":[{"given":"Qi","family":"Sun","sequence":"first","affiliation":[{"name":"Affiliated Baotou Clinical College of Inner Mongolia Medical University , No. 61 Hucheng Road, Donghe District, Baotou City, Inner Mongolia Autonomous Region 014040 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Yu","sequence":"additional","affiliation":[{"name":"Hepatobiliary and Splenic Surgery, Baotou Central Hospital, The Nei Monggol Autonomous Region , No. 61 Hucheng Road, Donghe District, Baotou City, Inner Mongolia Autonomous Region 014040 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lei","family":"Song","sequence":"additional","affiliation":[{"name":"Hepatobiliary and Splenic Surgery, Baotou Central Hospital, The Nei Monggol Autonomous Region , No. 61 Hucheng Road, Donghe District, Baotou City, Inner Mongolia Autonomous Region 014040 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lu","family":"Liang","sequence":"additional","affiliation":[{"name":"Hepatobiliary and Splenic Surgery, Baotou Central Hospital, The Nei Monggol Autonomous Region , No. 61 Hucheng Road, Donghe District, Baotou City, Inner Mongolia Autonomous Region 014040 ,","place":["China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,8,12]]},"reference":[{"key":"2025081221211631400_ref1","doi-asserted-by":"publisher","first-page":"76","DOI":"10.5582\/irdr.2015.01002","article-title":"A systematic review of hereditary spherocytosis reported in Chinese biomedical journals from 1978 to 2013 and estimation of the prevalence of the disease using a disease model","volume":"4","author":"Wang","year":"2015","journal-title":"Intractable Rare Dis Res"},{"key":"2025081221211631400_ref2","doi-asserted-by":"publisher","first-page":"366","DOI":"10.3126\/kumj.v13i4.16839","article-title":"Hereditary spherocytosis with splenomegaly and cholelithiasis in a young male of western region of Nepal\u2014a case report","volume":"13","author":"Ghimire","year":"2017","journal-title":"Kathmandu Univ Med J (KUMJ)"},{"key":"2025081221211631400_ref3","first-page":"1659","volume-title":"Nelson, Textbook of Pediatrics","author":"Segel","year":"2011","edition":"19th"},{"key":"2025081221211631400_ref4","doi-asserted-by":"publisher","first-page":"409","DOI":"10.1016\/S0022-3476(05)81081-9","article-title":"Variable clinical severity of hereditary spherocytosis: relation to erythrocytic spectrin concentration, osmotic fragility, and autohemolysis","volume":"117","author":"Eber","year":"1990","journal-title":"J Pediatr"},{"key":"2025081221211631400_ref5","first-page":"145","article-title":"Hereditary spherocytosis","volume":"2","author":"Bajracharya","year":"2003","journal-title":"Kathmandu Univ Med J"},{"key":"2025081221211631400_ref6","doi-asserted-by":"publisher","first-page":"791","DOI":"10.1111\/j.1365-2141.2005.05956.x","article-title":"Near-total splenectomy for hereditary spherocytosis: clinical prospects in relation to disease severity","volume":"132","author":"Stoehr","year":"2010","journal-title":"Br J Haematol"},{"key":"2025081221211631400_ref7","doi-asserted-by":"publisher","first-page":"399","DOI":"10.1182\/blood.V97.2.399","article-title":"Long-term evaluation of the beneficial effect of subtotal splenectomy for management of hereditary spherocytosis","volume":"97","author":"Bader-Meunier","year":"2001","journal-title":"Blood"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/8\/rjaf602\/64030411\/rjaf602.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/8\/rjaf602\/64030411\/rjaf602.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,13]],"date-time":"2025-08-13T01:21:24Z","timestamp":1755048084000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf602\/8232816"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8]]},"references-count":7,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,3]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf602","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,8]]},"published":{"date-parts":[[2025,8]]},"article-number":"rjaf602"}}