{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T02:34:22Z","timestamp":1792290862201,"version":"4.4.0"},"reference-count":5,"publisher":"Oxford University Press (OUP)","issue":"9","license":[{"start":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T00:00:00Z","timestamp":1756857600000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Bilothorax is a rare and under-recognized complication of hepatobiliary interventions, especially cytoreductive surgeries and is associated with increased length of hospitalization, morbidity and mortality. There are \u02c2100 reported cases in the literature, and due to its rarity, no standardized diagnostic tests or treatment guidelines are currently available. We present a 58-year-old otherwise healthy woman with a history of recurrent ovarian cancer who underwent cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy with curative intent. Her postoperative course was complicated by delayed abdominal bile leak, followed by progressive respiratory decline which failed initial conservative treatments. She underwent drainage and frank bile was obtained. The patient ultimately responded to broad-spectrum antibiotics and the placement of dual intercostal-abdominal drainage catheters. This article highlights the diagnostic challenges of bilothorax, a rare condition with non-specific and varied presentations, particularly in the absence of thoracic trauma.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf681","type":"journal-article","created":{"date-parts":[[2025,8,22]],"date-time":"2025-08-22T11:42:06Z","timestamp":1755862926000},"source":"Crossref","is-referenced-by-count":1,"title":["Bilothorax following peritoneal cytoreductive surgery for recurrent ovarian cancer"],"prefix":"10.1093","volume":"2025","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-1645-8027","authenticated-orcid":false,"given":"Zhengchao","family":"Xu","sequence":"first","affiliation":[{"name":"Department of Peritonectomy and Liver Surgery, St George Hospital , W.R. Pitney Building, Chapel Street, Kogarah, NSW 2217, Sydney, NSW ,","place":["Australia"]},{"name":"School of Clinical Medicine, Wallace Wurth Building (C27), Cnr High St & Botany St, University of New South Wales , Kensington, NSW 2033 , Sydney,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Pappas","sequence":"additional","affiliation":[{"name":"Department of Peritonectomy and Liver Surgery, St George Hospital , W.R. Pitney Building, Chapel Street, Kogarah, NSW 2217, Sydney, NSW ,","place":["Australia"]},{"name":"School of Clinical Medicine, Wallace Wurth Building (C27), Cnr High St & Botany St, University of New South Wales , Kensington, NSW 2033 , Sydney,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3808-0774","authenticated-orcid":false,"given":"Mina","family":"Sarofim","sequence":"additional","affiliation":[{"name":"Department of Peritonectomy and Liver Surgery, St George Hospital , W.R. Pitney Building, Chapel Street, Kogarah, NSW 2217, Sydney, NSW ,","place":["Australia"]},{"name":"School of Clinical Medicine, Wallace Wurth Building (C27), Cnr High St & Botany St, University of New South Wales , Kensington, NSW 2033 , Sydney,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Con","family":"Manganas","sequence":"additional","affiliation":[{"name":"Department of Cardiothoracic Surgery, Acute Services Building, St George Hospital , Gray St, Kogarah, NSW 2217, Sydney ,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruwanthi","family":"Wijayawardana","sequence":"additional","affiliation":[{"name":"Department of Peritonectomy and Liver Surgery, St George Hospital , W.R. Pitney Building, Chapel Street, Kogarah, NSW 2217, Sydney, NSW ,","place":["Australia"]},{"name":"School of Clinical Medicine, Wallace Wurth Building (C27), Cnr High St & Botany St, University of New South Wales , Kensington, NSW 2033 , Sydney,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Morris","sequence":"additional","affiliation":[{"name":"Department of Peritonectomy and Liver Surgery, St George Hospital , W.R. Pitney Building, Chapel Street, Kogarah, NSW 2217, Sydney, NSW ,","place":["Australia"]},{"name":"School of Clinical Medicine, Wallace Wurth Building (C27), Cnr High St & Botany St, University of New South Wales , Kensington, NSW 2033 , Sydney,","place":["Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"286","published-online":{"date-parts":[[2025,9,3]]},"reference":[{"key":"2025090318591959900_ref1","doi-asserted-by":"publisher","first-page":"364","DOI":"10.1016\/j.resinv.2016.03.009","article-title":"A new diagnostic approach for bilious pleural effusion","volume":"54","author":"Saraya","year":"2016","journal-title":"Respir Investig"},{"key":"2025090318591959900_ref2","first-page":"21","article-title":"The green pleural effusion: a comprehensive review of the bilothorax with case series","volume":"4","author":"Austin","year":"2017","journal-title":"Pleura"},{"key":"2025090318591959900_ref3","doi-asserted-by":"publisher","first-page":"A4575","DOI":"10.1016\/j.chest.2023.07.2966","article-title":"Bilothorax: a systematic literature review of the rare entity","volume":"164","author":"Acharya","year":"2023","journal-title":"Chest"},{"key":"2025090318591959900_ref4","doi-asserted-by":"publisher","first-page":"e53","DOI":"10.1308\/147870810X12699662980637","article-title":"A dangerous pleural effusion","volume":"92","author":"Basu","year":"2010","journal-title":"Ann R Coll Surg Engl"},{"key":"2025090318591959900_ref5","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1016\/j.thorsurg.2012.10.009","article-title":"Decision making and algorithm for the management of pleural effusions","volume":"23","author":"Quinn","year":"2013","journal-title":"Thorac Surg Clin"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/9\/rjaf681\/64202926\/rjaf681.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/9\/rjaf681\/64202926\/rjaf681.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,3]],"date-time":"2025-09-03T22:59:22Z","timestamp":1756940362000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf681\/8247341"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":5,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf681","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2025,9,1]]},"article-number":"rjaf681"}}