{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T15:56:55Z","timestamp":1759334215645,"version":"build-2065373602"},"reference-count":8,"publisher":"Oxford University Press (OUP)","issue":"9","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Ehlers\u2013Danlos syndrome (EDS), a rare group of inherited connective tissue disorders caused by alterations in collagen synthesis, has the potential for disrupted tissue healing leading to morbidity in patients undergoing gastrointestinal surgery. There is a paucity of literature on the safety of metabolic and bariatric surgery (MBS) in individuals with a diagnosis of EDS. We report on the outcomes of a patient with hypermobile subtype EDS who underwent sleeve gastrectomy for management of class III obesity. The patient underwent revisional Roux-en-Y gastric bypass for insufficient weight loss, without increased morbidity. This report suggests that primary (stapled) and revisional (anastomotic) MBS are safe in individuals with hypermobile subtype EDS. However, there are 13 subtypes of EDS, and it is likely that each is associated with different levels of surgical risk. A thorough discussion of potential implications of a diagnosis of EDS should be part of informed consent for MBS.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf782","type":"journal-article","created":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T12:38:17Z","timestamp":1759235897000},"source":"Crossref","is-referenced-by-count":0,"title":["Outcomes of revisional bariatric surgery in patient with hypermobile Ehlers\u2013Danlos syndrome"],"prefix":"10.1093","volume":"2025","author":[{"given":"Alexander","family":"Friedman","sequence":"first","affiliation":[{"name":"Department of Surgery, Stanford School of Medicine, Surgical Services, VA Palo Alto Health Care System , 3801 Miranda Avenue, Palo Alto, CA, 94304 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Eisenberg","sequence":"additional","affiliation":[{"name":"Department of Surgery, Stanford School of Medicine, Surgical Services, VA Palo Alto Health Care System , 3801 Miranda Avenue, Palo Alto, CA, 94304 ,","place":["United States"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,9,30]]},"reference":[{"key":"2025093008374795100_ref1","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/ajmg.c.31552","article-title":"The 2017 international classification of the Ehlers-Danlos syndromes","volume":"175","author":"Malfait","year":"2017","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"2025093008374795100_ref2","doi-asserted-by":"publisher","first-page":"30","DOI":"10.7556\/jaoa.2020.012","article-title":"The many facets of hypermobile Ehlers-Danlos syndrome","volume":"120","author":"Riley","year":"2020","journal-title":"J Osteopathic Med"},{"key":"2025093008374795100_ref3","doi-asserted-by":"publisher","first-page":"349","DOI":"10.1159\/000343738","article-title":"Gastrointestinal surgery and related complications in patients with Ehlers-Danlos syndrome: a systematic review","volume":"29","author":"Burcharth","year":"2012","journal-title":"Dig Surg"},{"key":"2025093008374795100_ref4","doi-asserted-by":"publisher","first-page":"600","DOI":"10.1016\/j.soard.2016.11.007","article-title":"Systems innovation model: an integrated interdisciplinary team approach pre- and post-bariatric surgery at a Veterans Affairs (VA) medical center","volume":"13","author":"Eisenberg","year":"2017","journal-title":"Surg Obes Relat Dis"},{"key":"2025093008374795100_ref5","doi-asserted-by":"publisher","first-page":"161","DOI":"10.1159\/000449106","article-title":"Increased need for gastrointestinal surgery and increased risk of surgery-related complications in patients with Ehlers-Danlos syndrome: a systematic review","volume":"34","author":"S\u00f8borg","year":"2017","journal-title":"Dig Surg"},{"key":"2025093008374795100_ref6","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1111\/codi.14749","article-title":"Management of colonic complications of type IV Ehlers-Danlos syndrome: a systematic review and evidence-based management strategy","volume":"22","author":"Speake","year":"2020","journal-title":"Colorectal Dis"},{"key":"2025093008374795100_ref8","doi-asserted-by":"publisher","first-page":"4168","DOI":"10.1007\/s11695-021-05453-3","article-title":"Experience with vertical sleeve gastrectomy in adolescent and young adult Ehlers-Danlos syndrome patients: a case series and review of the literature","volume":"31","author":"Herdes","year":"2021","journal-title":"Obes Surg"},{"key":"2025093008374795100_ref7","doi-asserted-by":"publisher","first-page":"1328","DOI":"10.1016\/j.soard.2020.03.033","article-title":"Bariatric surgery is feasible in patients with Ehlers-Danlos syndrome","volume":"16","author":"Verdure","year":"2020","journal-title":"Surg Obes Relat Dis"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/9\/rjaf782\/64441421\/rjaf782.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/9\/rjaf782\/64441421\/rjaf782.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,30]],"date-time":"2025-09-30T12:38:17Z","timestamp":1759235897000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf782\/8268772"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,1]]},"references-count":8,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9,1]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf782","relation":{},"ISSN":["2042-8812"],"issn-type":[{"type":"electronic","value":"2042-8812"}],"subject":[],"published-other":{"date-parts":[[2025,9]]},"published":{"date-parts":[[2025,9,1]]},"article-number":"rjaf782"}}