{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,3]],"date-time":"2025-10-03T00:54:35Z","timestamp":1759452875345,"version":"build-2065373602"},"reference-count":15,"publisher":"Oxford University Press (OUP)","issue":"10","license":[{"start":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T00:00:00Z","timestamp":1759363200000},"content-version":"vor","delay-in-days":2,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,9,30]]},"abstract":"<jats:title>Abstract<\/jats:title>\n               <jats:p>Treatment of locally recurrent rectal cancer (LRRC) after surgery is often complex and challenging. A 52-year-old man received emergency surgery (Hartmann\u2019s procedure) for bowel perforation caused by a huge sigmoid colon cancer, followed by treatment for concurrent advanced lower rectal cancer with neoadjuvant chemoradiotherapy and abdominoperineal resection. A solitary lung metastasis emerged afterwards, and was surgically removed. However, the patient developed LRRC in front of the sacrum. As surgical resection for the local recurrence was considered too invasive, carbon-ion radiotherapy (CIRT) was performed as radical local therapy. Because the surrounding intestine was highly adherent to the tumor and there was a high risk of developing an ulcer, the intestine was prophylactically resected. The patient has remained relapse-free for 2\u00a0years and 6\u00a0months since the most recent surgery. CIRT for LRRC appears to represent a useful therapeutic option in combination with prophylactic intestinal resection.<\/jats:p>","DOI":"10.1093\/jscr\/rjaf788","type":"journal-article","created":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T18:18:37Z","timestamp":1759429117000},"source":"Crossref","is-referenced-by-count":0,"title":["Prophylactic intestinal resection following carbon-ion radiotherapy for locally recurrent rectal cancer: a case report"],"prefix":"10.1093","volume":"2025","author":[{"given":"Takaki","family":"Furuyama","sequence":"first","affiliation":[{"name":"Department of Surgery, Tokyo Kyosai Hospital , 2-3-8 Nakameguro, Meguro-ku, Tokyo 153-8934 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotoshi","family":"Takiyama","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, QST Hospital, National Institute for Quantum Science and Technology , 4-9-1 Anagawa, Inage-ku, Chiba 263-8555 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ito","family":"Kondo","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokyo Kyosai Hospital , 2-3-8 Nakameguro, Meguro-ku, Tokyo 153-8934 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megumu","family":"Enjyoji","sequence":"additional","affiliation":[{"name":"Department of Surgery, JA Toride Medical Center , 2-1-1 Hongo, Toride-city, Ibaraki 302-0022 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Hinokida","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokyo Kyosai Hospital , 2-3-8 Nakameguro, Meguro-ku, Tokyo 153-8934 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yusuke","family":"Tatsutomi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokyo Kyosai Hospital , 2-3-8 Nakameguro, Meguro-ku, Tokyo 153-8934 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kunihiko","family":"Nakazawa","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokyo Kyosai Hospital , 2-3-8 Nakameguro, Meguro-ku, Tokyo 153-8934 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shigeru","family":"Yamada","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, QST Hospital, National Institute for Quantum Science and Technology , 4-9-1 Anagawa, Inage-ku, Chiba 263-8555 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshio","family":"Ushirokoji","sequence":"additional","affiliation":[{"name":"Department of Surgery, Tokyo Kyosai Hospital , 2-3-8 Nakameguro, Meguro-ku, Tokyo 153-8934 ,","place":["Japan"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"286","published-online":{"date-parts":[[2025,10,2]]},"reference":[{"key":"2025100214183270700_ref1","doi-asserted-by":"publisher","first-page":"447","DOI":"10.1245\/s10434-006-9256-9","article-title":"A population-based study on the management and outcome in patients with locally recurrent rectal cancer","volume":"14","author":"Palmer","year":"2006","journal-title":"Ann Surg Oncol"},{"key":"2025100214183270700_ref2","doi-asserted-by":"publisher","first-page":"6018","DOI":"10.3748\/wjg.14.6018","article-title":"Management of recurrent rectal cancer: a population based study in greater Amsterdam","volume":"14","author":"Bakx","year":"2008","journal-title":"World J Gastroenterol"},{"key":"2025100214183270700_ref3","doi-asserted-by":"publisher","first-page":"1243","DOI":"10.1007\/s00384-021-03856-3","article-title":"Treatment and subsequent prognosis in locally recurrent rectal cancer: a multicenter retrospective study of 498 patients","volume":"36","author":"Matsuyama","year":"2021","journal-title":"Int J Colorectal Dis"},{"key":"2025100214183270700_ref4","doi-asserted-by":"publisher","first-page":"323","DOI":"10.1097\/SLA.0000000000001524","article-title":"The outcomes and patterns of treatment failure after surgery for locally recurrent rectal cancer","volume":"264","author":"Harris","year":"2016","journal-title":"Ann Surg"},{"key":"2025100214183270700_ref5","doi-asserted-by":"publisher","first-page":"448","DOI":"10.1016\/j.ejso.2019.10.037","article-title":"Locally recurrent rectal cancer; long-term outcome of curative surgical and non-surgical treatment of 447 consecutive patients in a tertiary referral Centre","volume":"46","author":"Hagemans","year":"2020","journal-title":"Eur J Surg Oncol"},{"key":"2025100214183270700_ref6","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1002\/bjs.10079","article-title":"Improved long-term salvage potential of locally recurrent rectal cancer with evolving multimodality therapy","volume":"103","author":"You","year":"2016","journal-title":"Br J Surg"},{"key":"2025100214183270700_ref7","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1016\/j.ejso.2017.11.013","article-title":"Management and prognosis of locally recurrent rectal cancer - a national population-based study","volume":"44","author":"Westberg","year":"2018","journal-title":"Eur J Surg Oncol"},{"key":"2025100214183270700_ref8","doi-asserted-by":"publisher","first-page":"2677","DOI":"10.1245\/s10434-014-4317-y","article-title":"Early and late outcomes of surgery for locally recurrent rectal cancer: a prospective 10-year study in the total mesorectal excision era","volume":"22","author":"Nielsen","year":"2015","journal-title":"Ann Surg Oncol"},{"key":"2025100214183270700_ref9","doi-asserted-by":"publisher","first-page":"779","DOI":"10.1007\/DCR.0b013e3181cf7609","article-title":"Prediction of residual disease or distant metastasis after resection of locally recurrent rectal cancer","volume":"53","author":"Kanemitsu","year":"2010","journal-title":"Dis Colon Rectum"},{"key":"2025100214183270700_ref10","doi-asserted-by":"publisher","first-page":"93","DOI":"10.1016\/j.ijrobp.2016.04.022","article-title":"Carbon-ion radiation therapy for pelvic recurrence of rectal cancer","volume":"96","author":"Yamada","year":"2016","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2025100214183270700_ref11","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1016\/j.radonc.2018.10.007","article-title":"Carbon-ion radiotherapy for locally recurrent rectal cancer: Japan carbon-ion radiation oncology study group (J-CROS) study 1404 rectum","volume":"132","author":"Shinoto","year":"2019","journal-title":"Radiother Oncol"},{"key":"2025100214183270700_ref12","doi-asserted-by":"publisher","first-page":"99","DOI":"10.1245\/s10434-021-10876-4","article-title":"Carbon ion radiotherapy for locally recurrent rectal cancer of patients with prior pelvic irradiation","volume":"29","author":"Yamada","year":"2022","journal-title":"Ann Surg Oncol"},{"key":"2025100214183270700_ref13","doi-asserted-by":"publisher","first-page":"692","DOI":"10.1007\/s00595-006-3231-8","article-title":"The effects of carbon ion irradiation revealed by excised perforated intestines as a late morbidity for uterine cancer treatment","volume":"36","author":"Matsushita","year":"2006","journal-title":"Surg Today"},{"key":"2025100214183270700_ref14","doi-asserted-by":"publisher","first-page":"388","DOI":"10.1016\/j.ijrobp.2005.12.050","article-title":"Dose escalation study of carbon ion radiotherapy for locally advanced carcinoma of the uterine cervix","volume":"65","author":"Kato","year":"2006","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"2025100214183270700_ref15","doi-asserted-by":"publisher","first-page":"2339","DOI":"10.3390\/tomography8050195","article-title":"Visualizing bioabsorbable spacer effectiveness by confirming the distal-tail of carbon-ion beams: first-in-human report","volume":"8","author":"Shiba","year":"2022","journal-title":"Tomography"}],"container-title":["Journal of Surgical Case Reports"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/10\/rjaf788\/64473024\/rjaf788.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/academic.oup.com\/jscr\/article-pdf\/2025\/10\/rjaf788\/64473024\/rjaf788.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,2]],"date-time":"2025-10-02T18:18:38Z","timestamp":1759429118000},"score":1,"resource":{"primary":{"URL":"https:\/\/academic.oup.com\/jscr\/article\/doi\/10.1093\/jscr\/rjaf788\/8271055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,30]]},"references-count":15,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,9,30]]}},"URL":"https:\/\/doi.org\/10.1093\/jscr\/rjaf788","relation":{},"ISSN":["2042-8812"],"issn-type":[{"value":"2042-8812","type":"electronic"}],"subject":[],"published-other":{"date-parts":[[2025,10]]},"published":{"date-parts":[[2025,9,30]]},"article-number":"rjaf788"}}